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Fig. 5. Treatment option for major depressive disorders-Created with BioRender.com.
Figure 7. Fig. 5. Treatment option for major depressive disorders-Created with BioRender.com.

Description

Treatment options for major depressive disorders are presented, including pharmacological, psychological, and lifestyle interventions that address the inflammatory-metabolic axis.

More Figures from This Paper

Brain insulin resistance mechanisms underlying depression are depicted, showing how HPA axis dysregulation, reduced anterior cingulate cortex volume, and impaired hippocampal function contribute to the condition.

Figure 3

Brain insulin resistance mechanisms underlying depression are depicted, showing how HPA axis dysregulation, reduced anterior cingulate cortex volume, and impaired hippocampal function contribute to the condition.

diagram
Obesity, diabetes, and metabolic syndrome are illustrated as metabolic diseases that commonly coexist with depression, highlighting their shared pathophysiological mechanisms through chronic low-grade inflammation.

Figure 4

Obesity, diabetes, and metabolic syndrome are illustrated as metabolic diseases that commonly coexist with depression, highlighting their shared pathophysiological mechanisms through chronic low-grade inflammation.

diagram
Molecular pathways connecting stress-induced inflammation to insulin resistance are detailed, tracing how inflammatory signaling cascades impair insulin receptor substrate phosphorylation.

Figure 5

Molecular pathways connecting stress-induced inflammation to insulin resistance are detailed, tracing how inflammatory signaling cascades impair insulin receptor substrate phosphorylation.

diagram
Bidirectional relationships between depression and metabolic disturbances are outlined, showing how each condition exacerbates the other through shared inflammatory and neuroendocrine mechanisms.

Figure 6

Bidirectional relationships between depression and metabolic disturbances are outlined, showing how each condition exacerbates the other through shared inflammatory and neuroendocrine mechanisms.

diagram
A schematic representation maps the factors contributing to metabolic syndrome alongside corresponding dietary and lifestyle modifications that may alleviate these conditions, integrating evidence on stress management and anti-inflammatory nutrition.

Figure 8

A schematic representation maps the factors contributing to metabolic syndrome alongside corresponding dietary and lifestyle modifications that may alleviate these conditions, integrating evidence on stress management and anti-inflammatory nutrition.

diagram

Figure 7

Diagram
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Source Paper

A review on linking stress, depression, and insulin resistance via low-grade chronic inflammation.

Biochemistry and biophysics reports (2023)

PMID: 37965066

DOI: 10.1016/j.bbrep.2023.101571

Cite This Figure

![Figure 7: Treatment options for major depressive disorders are presented, including pharmacological, psychological, and lifestyle interventions that address the inflammatory-metabolic axis.](https://pdfs.citedhealth.com/figures/37965066/171.png)

> Source: Seema Mehdi et al. "A review on linking stress, depression, and insulin resistance via low-grade chr." *Biochemistry and biophysics reports*, 2023. PMID: [37965066](https://pubmed.ncbi.nlm.nih.gov/37965066/)
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  <img src="https://pdfs.citedhealth.com/figures/37965066/171.png" alt="Treatment options for major depressive disorders are presented, including pharmacological, psychological, and lifestyle interventions that address the inflammatory-metabolic axis." />
  <figcaption>Figure 7. Treatment options for major depressive disorders are presented, including pharmacological, psychological, and lifestyle interventions that address the inflammatory-metabolic axis.<br>  Source: Seema Mehdi et al. "A review on linking stress, depression, and insulin resistance via low-grade chr." <em>Biochemistry and biophysics reports</em>, 2023. PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/37965066/">37965066</a></figcaption>
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