What is the recommended dosage for Bovine Colostrum?

General: 1-5 g/day; Immune Support: 3-10 g/day

What are the side effects of Bovine Colostrum?

Potential side effects include: Gastrointestinal discomfort (nausea, bloating), Not suitable for those with cow's milk allergy, Mild diarrhea at high doses.

What is colostrum and how does it relate to immune health?

Bovine colostrum is the first milk produced after calving, rich in immunoglobulins (IgG), lactoferrin, and growth factors. Studies have explored its potential to support mucosal immunity and reduce the incidence of upper respiratory infections.

What dosage of colostrum has been used in clinical studies?

Clinical trials have used bovine colostrum at doses of 10–60 g per day for powdered forms, or 400–500 mg per day for concentrated immunoglobulin extracts. Study durations typically range from 8 to 12 weeks.

What are the potential side effects of colostrum supplementation?

Colostrum is generally well tolerated. Mild gastrointestinal discomfort may occur. Individuals with dairy allergies or lactose intolerance should exercise caution. Quality and immunoglobulin content can vary between products.

Bovine Colostrum

other

Also known as: Bovine Colostrum, First Milk, Colostrum Concentrate

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About

Bovine colostrum is rich in immunoglobulins (IgG, IgA, IgM), lactoferrin, growth factors, and cytokines that directly support mucosal immunity. Proline-rich polypeptides (PRPs) modulate immune function by promoting Th1 and Th2 immune balance. An RCT in children with recurrent infections showed significant reduction in infections and hospitalizations.

How It Works

Rich in immunoglobulins (IgG, IgA, IgM), lactoferrin, growth factors, and cytokines; PRPs modulate immune function by promoting Th1 and Th2 immune balance; supports GALT integrity.

Evidence For Conditions

Condition	Grade	Studies	Participants
Recurrent Infections	B	5	500	View →

Side Effects

Gastrointestinal discomfort (nausea, bloating)
Not suitable for those with cow's milk allergy
Mild diarrhea at high doses

Drug & Supplement Interactions

Generally few known drug interactions
May interact with immunosuppressant medications (contains immune factors)

Always inform your healthcare provider about all supplements you take.

Related Ingredients

Beta-Glucan Lactoferrin Spirulina

Quick Facts

Dosage: General: 1-5 g/day; Immune_Support: 3-10 g/day
Forms: capsule powder tablet chewable
Natural Sources: Bovine colostrum (first milk from cows within 24-72 hours of calving)
Upper Limit: No established UL; generally well-tolerated
Best Time: On empty stomach, 30 minutes before meals

Evidence Summary

Recurrent Infections B

FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. The products and information on this website are not intended to diagnose, treat, cure, or prevent any disease. The evidence grades presented are based on our analysis of published peer-reviewed research and do not constitute medical advice. Always consult your healthcare provider before starting any supplement regimen.