What is the recommended dosage for Garlic?

Fresh: 2-5 g raw garlic/day; General: 600-1,200 mg aged garlic extract/day

What are the side effects of Garlic?

Potential side effects include: Gastrointestinal discomfort (heartburn, gas, nausea), Body and breath odor, Increased bleeding risk, Allergic reactions (contact dermatitis, rare).

What is garlic and how does it support the immune system?

Garlic (Allium sativum) contains allicin and organosulfur compounds that have been studied for antimicrobial and immune-modulating properties. Clinical research has examined aged garlic extract for its potential to enhance natural killer cell function and reduce cold incidence.

What dosage of garlic has been used in immune studies?

Studies have used various garlic preparations, including 2.56 g per day of aged garlic extract and 180 mg of allicin-standardized extract. Fresh garlic equivalents range from 2–5 g (roughly 1–2 cloves) per day.

What are the potential side effects of garlic supplementation?

Common side effects include garlic breath, body odor, and gastrointestinal discomfort. Garlic has antiplatelet properties and may interact with blood-thinning medications. Supplementation should be discontinued 1–2 weeks before planned surgery.

Garlic

herb

Also known as: Allium sativum, Aged Garlic Extract, Allicin

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About

Garlic contains organosulfur compounds (allicin, diallyl disulfide) that stimulate macrophage, lymphocyte, and NK cell activity, modulate cytokine secretion, and exhibit broad-spectrum antimicrobial activity. A 12-week RCT showed the garlic group had significantly fewer colds and shorter symptom duration.

How It Works

Organosulfur compounds (allicin, diallyl disulfide) stimulate macrophage, lymphocyte, and NK cell activity; modulate cytokine secretion; exhibit broad-spectrum antimicrobial activity via S-thioallylation of protein thiols.

Evidence For Conditions

Condition	Grade	Studies	Participants
Upper Respiratory Tract Infections	B	3	300	View →

Side Effects

Gastrointestinal discomfort (heartburn, gas, nausea)
Body and breath odor
Increased bleeding risk
Allergic reactions (contact dermatitis, rare)

Drug & Supplement Interactions

Anticoagulants and antiplatelet drugs (may increase bleeding risk)
HIV protease inhibitors (saquinavir — may reduce drug levels)
CYP2E1 substrates (garlic may alter metabolism)
Isoniazid (may reduce drug absorption)

Always inform your healthcare provider about all supplements you take.

Related Ingredients

Andrographis Astragalus Echinacea Elderberry Olive Leaf Extract

Quick Facts

Dosage: Fresh: 2-5 g raw garlic/day; General: 600-1,200 mg aged garlic extract/day
Forms: capsule tablet aged garlic extract powder oil
Natural Sources: Fresh garlic cloves
Upper Limit: No established UL; high doses may increase bleeding risk
Best Time: With meals to reduce GI discomfort

Evidence Summary

Upper Respiratory Tract Infections B

FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. The products and information on this website are not intended to diagnose, treat, cure, or prevent any disease. The evidence grades presented are based on our analysis of published peer-reviewed research and do not constitute medical advice. Always consult your healthcare provider before starting any supplement regimen.