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Figure 1. Gut dysbiosis promotes intestinal and systemic inflammation with consequently Aβ aggregation and neuroinflammation finally leading to neurodegeneration and Alzheimer’s disease. Abbreviations: Aβ = amyloid beta; PP = polyphenols; SCFA = short chain
Figure 6. Figure 1. Gut dysbiosis promotes intestinal and systemic inflammation with consequently Aβ aggregation and neuroinflammation finally leading to neurodegeneration and Alzheimer’s disease. Abbreviations: Aβ = amyloid beta; PP = polyphenols; SCFA = short chain fatty acids; TMAO = trimethylamine N-oxide; IL = interleukin; TNF = tumor necrosis factor; BBB = blood brain barrier.

설명

A pathway diagram illustrates how gut dysbiosis promotes intestinal and systemic inflammation, leading to amyloid-beta aggregation, neuroinflammation, and ultimately neurodegeneration in Alzheimer's disease. The cascade connects microbial imbalance to blood-brain barrier compromise and central nervous system pathology.

More Figures from This Paper

Western diet-induced microbiome changes are mapped to intestinal dysbiosis, low-grade gut inflammation, and increased permeability of both the intestinal barrier and blood-brain barrier. The resulting systemic inflammatory state is linked to neuroinflammatory processes implicated in Alzheimer's disease progression.

Figure 7

Western diet-induced microbiome changes are mapped to intestinal dysbiosis, low-grade gut inflammation, and increased permeability of both the intestinal barrier and blood-brain barrier. The resulting systemic inflammatory state is linked to neuroinflammatory processes implicated in Alzheimer's disease progression.

diagram

Figure 6

Diagram
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Source Paper

The Immunopathogenesis of Alzheimer's Disease Is Related to the Composition of Gut Microbiota.

Nutrients (2021)

PMID: 33504065

DOI: 10.3390/nu13020361

Cite This Figure

![Figure 6: A pathway diagram illustrates how gut dysbiosis promotes intestinal and systemic inflammation, leading to amyloid-beta aggregation, neuroinflammation, and ultimately neurodegeneration in Alzheimer's disease. The cascade connects microbial imbalance to blood-brain barrier compromise and central nervous system pathology.](https://pdfs.citedhealth.com/figures/33504065/128.png)

> Source: Friedrich Leblhuber et al. "The Immunopathogenesis of Alzheimer's Disease Is Related to the Composition of G." *Nutrients*, 2021. PMID: [33504065](https://pubmed.ncbi.nlm.nih.gov/33504065/)
<figure>
  <img src="https://pdfs.citedhealth.com/figures/33504065/128.png" alt="A pathway diagram illustrates how gut dysbiosis promotes intestinal and systemic inflammation, leading to amyloid-beta aggregation, neuroinflammation, and ultimately neurodegeneration in Alzheimer's disease. The cascade connects microbial imbalance to blood-brain barrier compromise and central nervous system pathology." />
  <figcaption>Figure 6. A pathway diagram illustrates how gut dysbiosis promotes intestinal and systemic inflammation, leading to amyloid-beta aggregation, neuroinflammation, and ultimately neurodegeneration in Alzheimer's disease. The cascade connects microbial imbalance to blood-brain barrier compromise and central nervous system pathology.<br>  Source: Friedrich Leblhuber et al. "The Immunopathogenesis of Alzheimer's Disease Is Related to the Composition of G." <em>Nutrients</em>, 2021. PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/33504065/">33504065</a></figcaption>
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