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Figure 4. Astaxanthin inhibits glucose/glucose oxidase (G/GO)−induced decrease in Ku70/80 levels in whole-cell extracts and nuclear extracts in AGS cells. The cells were (A) treated with G/GO for the indicated time periods or (B) pre−treated with the indi
Figure 13. Figure 4. Astaxanthin inhibits glucose/glucose oxidase (G/GO)−induced decrease in Ku70/80 levels in whole-cell extracts and nuclear extracts in AGS cells. The cells were (A) treated with G/GO for the indicated time periods or (B) pre−treated with the indicated concentrations of astaxanthin for 3 h, followed by stimulation with G/GO for 8 h. (A,B) Ku70 and 80 protein levels in the whole cell and nuclear extracts were determined by Western blot analysis using actin and lamin B1 as the loading control and nuclear marker, respectively (left panel). The densitometry data represent mean ± standard error (SE) from three immunoblots and are shown as the relative density of the actin or lamin B1 protein bands (right panel). * p < 0.05 vs. untreated cells (AST− and G/GO−). + p < 0.05 vs. control cells (AST− and G/GO+: cells without astaxanthin treatment in the presence of G/GO). AST, astaxanthin.

Descrição

Astaxanthin inhibits glucose/glucose oxidase (G/GO)−induced decrease in Ku70/80 levels in whole-cell extracts and nuclear extracts in AGS cells. The cells were (A) treated with G/GO for the indicated time periods or (B) pre−treated with the indicated concentrations of astaxanthin for 3 h, followed by stimulation with G/GO for 8 h.

More Figures from This Paper

Experimental results examining astaxanthin Inhibits Oxidative Stress, with data points illustrating key findings related to oxidative stress induces DNA damage which can be repaired by DNA repair proteins, such as Ku70/80.

Figure 6

Experimental results examining astaxanthin Inhibits Oxidative Stress, with data points illustrating key findings related to oxidative stress induces DNA damage which can be repaired by DNA repair proteins, such as Ku70/80.

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Statistical analysis from research investigating astaxanthin Inhibits Oxidative Stress, comparing treatment groups and control conditions.

Figure 7

Statistical analysis from research investigating astaxanthin Inhibits Oxidative Stress, comparing treatment groups and control conditions.

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Glucose/glucose oxidase (G/GO) treatment induced cell death, DNA fragmentation, and apoptosis in AGS cells. The cells were stimulated with G/GO for the indicated periods.

Figure 8

Glucose/glucose oxidase (G/GO) treatment induced cell death, DNA fragmentation, and apoptosis in AGS cells. The cells were stimulated with G/GO for the indicated periods.

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cells in G/GO-treated cells (Figure 2C,D). These data show that astaxanthin inhibits G/GOinduced cell death, DNA fragmentation, and apoptosis in AGS cells in a dose-dependent manner.

Figure 9

cells in G/GO-treated cells (Figure 2C,D). These data show that astaxanthin inhibits G/GOinduced cell death, DNA fragmentation, and apoptosis in AGS cells in a dose-dependent manner.

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Quantitative data from a study on astaxanthin Inhibits Oxidative Stress, presenting measured outcomes relevant to the investigation of oxidative stress induces DNA damage which can be repaired by DNA repair proteins, such as Ku70/80.

Figure 10

Quantitative data from a study on astaxanthin Inhibits Oxidative Stress, presenting measured outcomes relevant to the investigation of oxidative stress induces DNA damage which can be repaired by DNA repair proteins, such as Ku70/80.

chart
Experimental results examining astaxanthin Inhibits Oxidative Stress, with data points illustrating key findings related to oxidative stress induces DNA damage which can be repaired by DNA repair proteins, such as Ku70/80.

Figure 11

Experimental results examining astaxanthin Inhibits Oxidative Stress, with data points illustrating key findings related to oxidative stress induces DNA damage which can be repaired by DNA repair proteins, such as Ku70/80.

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Figure 13

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Source Paper

Astaxanthin Inhibits Oxidative Stress-Induced Ku Protein Degradation and Apoptosis in Gastric Epithelial Cells.

Nutrients (2022)

PMID: 36235593

DOI: 10.3390/nu14193939

Cite This Figure

![Figure 13: Astaxanthin inhibits glucose/glucose oxidase (G/GO)−induced decrease in Ku70/80 levels in whole-cell extracts and nuclear extracts in AGS cells. The cells were (A) treated with G/GO for the indicated time periods or (B) pre−treated with the indicated concentrations of astaxanthin for 3 h, followed by stimulation with G/GO for 8 h.](https://pdfs.citedhealth.com/figures/36235593/182.png)

> Source: Jaeeun Lee et al. "Astaxanthin Inhibits Oxidative Stress-Induced Ku Protein Degradation and Apoptos." *Nutrients*, 2022. PMID: [36235593](https://pubmed.ncbi.nlm.nih.gov/36235593/)
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  <img src="https://pdfs.citedhealth.com/figures/36235593/182.png" alt="Astaxanthin inhibits glucose/glucose oxidase (G/GO)−induced decrease in Ku70/80 levels in whole-cell extracts and nuclear extracts in AGS cells. The cells were (A) treated with G/GO for the indicated time periods or (B) pre−treated with the indicated concentrations of astaxanthin for 3 h, followed by stimulation with G/GO for 8 h." />
  <figcaption>Figure 13. Astaxanthin inhibits glucose/glucose oxidase (G/GO)−induced decrease in Ku70/80 levels in whole-cell extracts and nuclear extracts in AGS cells. The cells were (A) treated with G/GO for the indicated time periods or (B) pre−treated with the indicated concentrations of astaxanthin for 3 h, followed by stimulation with G/GO for 8 h.<br>  Source: Jaeeun Lee et al. "Astaxanthin Inhibits Oxidative Stress-Induced Ku Protein Degradation and Apoptos." <em>Nutrients</em>, 2022. PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/36235593/">36235593</a></figcaption>
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