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Saccharomyces boulardii для Gut Immune Health

B

Meta-analyses support Saccharomyces boulardii for the prevention of antibiotic-associated diarrhea and C. difficile infection. Its unique antibiotic resistance allows concurrent use during antibiotic therapy, supporting gut immune recovery.

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            B

        

        

            
Итог

            
            
Meta-analyses support Saccharomyces boulardii for the prevention of antibiotic-associated diarrhea and C. difficile infection. Its unique antibiotic resistance allows concurrent use during antibiotic therapy, supporting gut immune recovery.

            
            
        

    










    

  
Key Study Findings





    

        
        

            

                
                    In Vitro
                
                
                
                
            

            
                Genetically engineered probiotic Saccharomyces cerevisiae strains mature human dendritic cells and stimulate Gag-specific memory CD8+ …
            
            

                
                Dose: 1 G
                
                
                или: None
                
                
                Outcome: None
                
                
                Эффект: None
                
                
                None
                
            

            
            
Популяция: None

            
        

        
        

            

                
                    Review
                
                
                
                
            

            
                The role of probiotics and prebiotics in inducing gut immunity.
            
            

                
                Dose: None
                
                
                или: None
                
                
                Outcome: Gut immune system modulation
                
                
                Эффект: None
                
                
                None
                
            

            
            
Популяция: Preclinical and clinical subjects

            
        

        
    







    
    

        
        

            

  
Key Statistics





            


    

        
15

        
Исследования

    

    

        
3000

        
Участники

    

    

        
            
            ↑
            
        
        
Positive

    

    

        B

        
Оценка

    




        


        
        
        

            

  
Referenced Papers





            

                
                

                    

                        
                            Genetically engineered probiotic Saccharomyces cerevisiae strains mature human dendritic cells and stimulate Gag-specific memory CD8+ T cells ex vivo.
                        
                        
                            
                                Other
                            
                            
                            
                        
                    

                    

                        Applied microbiology and …
                        2019
                        
                        25 цитирований
                        
                    

                

                
                

                    

                        
                            The role of probiotics and prebiotics in inducing gut immunity.
                        
                        
                            
                                Review
                            
                            
                            
                        
                    

                    

                        Frontiers in immunology
                        2013
                        
                        263 цитирований
                        
                    

                

                
            

        

        

        
        
        

            

  
Dosage & Usage





            
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units


            
            

                
Часто используемые дозировки

                

                    
                    

                        
acute:

                        
250 mg 2x/day

                    

                    
                    

                        
general:

                        
250-500 mg/day (5-10 billion CFU)

                    

                    
                

                
                

                    Верхний предел: No established UL
                

                
            

            

            
            

                
Дозировки, изученные в исследованиях

                

                    

                        
                            

                                Дозировка
                                Длительность
                                Эффект
                                N
                            

                        
                        
                            
                            

                                1 G
                                --
                                
                                    
                                    Mixed
                                    
                                
                                --
                            

                            
                            

                                None
                                --
                                
                                    
                                    Positive
                                    
                                
                                --
                            

                            
                        
                    

                

            

            

            
            

                Лучшее время приёма: Can be taken with antibiotics (uniquely antibiotic-resistant)
            

            
        

        

        
        
        

            

  
Safety & Side Effects





            

                
                

                    
Зарегистрированные побочные эффекты

                    
    
                        
                        
  • 
                            ⚠
                            Mild bloating and gas
                        
    • 
                        
                        
  • 
                            ⚠
                            Rare: fungemia in severely immunocompromised or ICU patients with central lines
                        
    • 
                        
                        
  • 
                            ⚠
                            Constipation (rare)
                        
    • 
                        
                    

                

                

                
                

                    
Известные взаимодействия

                    
    
                        
                        
  • 
                            ●
                            Antifungal medications (will kill S. boulardii; do not combine)
                        
    • 
                        
                        
  • 
                            ●
                            Uniquely safe to use with antibiotics (inherent antibiotic resistance)
                        
    • 
                        
                    

                

                

                
                

                    

                        Допустимый верхний уровень потребления: No established UL
                    

                

                
            

            

                Всегда консультируйтесь с врачом перед началом приёма любых добавок.Всегда консультируйтесь с лечащим врачом перед началом приёма любой добавки.
            

        

        

        
        
        

            

  
Frequently Asked Questions





            




    
    

        
            Does Saccharomyces boulardii help with Gut Immune Health?
            
        
        

            Based on 15 studies with 3,000 participants, there is moderate evidence from clinical studies that Saccharomyces boulardii may support Gut Immune Health management. Our evidence grade is B (Good Evidence).
        

    

    
    

        
            How much Saccharomyces boulardii should I take for Gut Immune Health?
            
        
        

            Studies have used various dosages. A commonly studied range is 250 mg 2x/day. Always consult your healthcare provider before starting any supplement regimen.
        

    

    
    

        
            Are there side effects of Saccharomyces boulardii?
            
        
        

            Reported side effects may include Mild bloating and gas, Rare: fungemia in severely immunocompromised or ICU patients with central lines, Constipation (rare). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
        

    

    
    

        
            How strong is the evidence for Saccharomyces boulardii and Gut Immune Health?
            
        
        

            We rate the evidence as Grade B (Good Evidence). This rating is based on 15 peer-reviewed studies with 3,000 total participants. The overall direction of effect is positive.
        

    

    




        

        

        
        
        

            

  
Related Evidence





            

                
                

                    
Другие ингредиенты для Gut Immune Health

                    

                        
                        
                            Lactobacillus rhamnosus GG
                            B

                        
                        
                    

                

                

                
            

        

        

    


    
    












    

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