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Pathway diagram depicting Nrf2-mediated antioxidant defense in bone cells and the role of nutraceuticals in activating this protective signaling cascade.

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![Figure 3: Pathway diagram depicting Nrf2-mediated antioxidant defense in bone cells and the role of nutraceuticals in activating this protective signaling cascade.]()

> Source: Mark F McCarty et al. "Targeting Sirt1, AMPK, Nrf2, CK2, and Soluble Guanylate Cyclase with Nutraceutic." *International journal of molecular sciences*, 2022. PMID: [35563167](https://pubmed.ncbi.nlm.nih.gov/35563167/)
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  <img src="" alt="Pathway diagram depicting Nrf2-mediated antioxidant defense in bone cells and the role of nutraceuticals in activating this protective signaling cascade." />
  <figcaption>Figure 3. Pathway diagram depicting Nrf2-mediated antioxidant defense in bone cells and the role of nutraceuticals in activating this protective signaling cascade.<br>  Source: Mark F McCarty et al. "Targeting Sirt1, AMPK, Nrf2, CK2, and Soluble Guanylate Cyclase with Nutraceutic." <em>International journal of molecular sciences</em>, 2022. PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/35563167/">35563167</a></figcaption>
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