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Figure 1. Brain microglia activation in AD. Microglia are effective in Aβ clearance, neuroinflammation, and the production and aggregation of Aβ. Also, an Aβ pathologic increase in the brain and
Figure 1. Figure 1. Brain microglia activation in AD. Microglia are effective in Aβ clearance, neuroinflammation, and the production and aggregation of Aβ. Also, an Aβ pathologic increase in the brain and

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Brain microglia activation in AD. Microglia are effective in Aβ clearance, neuroinflammation, and the production and aggregation of Aβ.

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Visual summary of the pathways and interactions relevant to mechanisms Linking Obesity, Insulin Resistance, and Alzheimer's Disease, as discussed in the context of alzheimer's disease (AD) is a complex neurodegenerative disorder characterized by progressive cognitive decline, memo.

Figure 2

Visual summary of the pathways and interactions relevant to mechanisms Linking Obesity, Insulin Resistance, and Alzheimer's Disease, as discussed in the context of alzheimer's disease (AD) is a complex neurodegenerative disorder characterized by progressive cognitive decline, memo.

diagram
Schematic representation highlighting the mechanisms underlying mechanisms Linking Obesity, Insulin Resistance, and Alzheimer's Disease and their potential therapeutic implications.

Figure 3

Schematic representation highlighting the mechanisms underlying mechanisms Linking Obesity, Insulin Resistance, and Alzheimer's Disease and their potential therapeutic implications.

diagram
Summary of the mechanistic effects of dietary ω-3 fatty acids and polyphenols on the amyloidogenic pathway. In the context of obesity, IR, and the presence of Aβ, inflammatory pathways are upregulated.

Figure 4

Summary of the mechanistic effects of dietary ω-3 fatty acids and polyphenols on the amyloidogenic pathway. In the context of obesity, IR, and the presence of Aβ, inflammatory pathways are upregulated.

diagram

Figure 1

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Source Paper

Mechanisms Linking Obesity, Insulin Resistance, and Alzheimer's Disease: Effects of Polyphenols and Omega-3 Polyunsaturated Fatty Acids.

Nutrients (2025)

PMID: 40218960

DOI: 10.3390/nu17071203

Cite This Figure

![Figure 1: Brain microglia activation in AD. Microglia are effective in Aβ clearance, neuroinflammation, and the production and aggregation of Aβ.](https://pdfs.citedhealth.com/figures/40218960/79.png)

> Source: Mahsa Yavari et al. "Mechanisms Linking Obesity, Insulin Resistance, and Alzheimer's Disease: Effects." *Nutrients*, 2025. PMID: [40218960](https://pubmed.ncbi.nlm.nih.gov/40218960/)
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  <img src="https://pdfs.citedhealth.com/figures/40218960/79.png" alt="Brain microglia activation in AD. Microglia are effective in Aβ clearance, neuroinflammation, and the production and aggregation of Aβ." />
  <figcaption>Figure 1. Brain microglia activation in AD. Microglia are effective in Aβ clearance, neuroinflammation, and the production and aggregation of Aβ.<br>  Source: Mahsa Yavari et al. "Mechanisms Linking Obesity, Insulin Resistance, and Alzheimer's Disease: Effects." <em>Nutrients</em>, 2025. PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/40218960/">40218960</a></figcaption>
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