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Figure 5. Anti-inflammatory effects of curcumin: molecular and clinical evidence. Image shows the main mechanisms by which curcumin exerts anti-inflammatory effects both systemically and in adipocytes. At the molecular level, curcumin blocks inflammatory signa
Figure 7. Figure 5. Anti-inflammatory effects of curcumin: molecular and clinical evidence. Image shows the main mechanisms by which curcumin exerts anti-inflammatory effects both systemically and in adipocytes. At the molecular level, curcumin blocks inflammatory signals mediated by TLR4/MAPK and NF-κB in macrophages, reduces M1 polarization and inflammasome activation. In adipocytes, it decreases TNF-α and IL-1β levels, reduces endoplasmic reticulum stress (UPR), limits hypoxia

Mô tả

Anti-inflammatory effects of curcumin: molecular and clinical evidence. Image shows the main mechanisms by which curcumin exerts anti-inflammatory effects both systemically and in adipocytes.

More Figures from This Paper

Conceptual diagram summarizing the relationship between curcumin Modulation of the Gut and the biological processes described in this research.

Figure 1

Conceptual diagram summarizing the relationship between curcumin Modulation of the Gut and the biological processes described in this research.

diagram
Visual summary of the pathways and interactions relevant to curcumin Modulation of the Gut, as discussed in the context of curcumin, a polyphenolic compound derived from Curcuma longa, has gained significant attention for its potential ther.

Figure 2

Visual summary of the pathways and interactions relevant to curcumin Modulation of the Gut, as discussed in the context of curcumin, a polyphenolic compound derived from Curcuma longa, has gained significant attention for its potential ther.

diagram
Schematic representation highlighting the mechanisms underlying curcumin Modulation of the Gut and their potential therapeutic implications.

Figure 3

Schematic representation highlighting the mechanisms underlying curcumin Modulation of the Gut and their potential therapeutic implications.

diagram
Diagram illustrating the key biological concepts related to curcumin Modulation of the Gut, synthesizing evidence presented in the study.

Figure 4

Diagram illustrating the key biological concepts related to curcumin Modulation of the Gut, synthesizing evidence presented in the study.

diagram
Illustrative overview of the mechanisms involved in curcumin Modulation of the Gut, depicting key molecular and cellular pathways.

Figure 5

Illustrative overview of the mechanisms involved in curcumin Modulation of the Gut, depicting key molecular and cellular pathways.

diagram
The Keap1-NRF2 pathway. Under normal conditions, Keap1 behaves as a negative regulator of NRF2, preventing its activation and thereby inhibiting its antioxidant response.

Figure 6

The Keap1-NRF2 pathway. Under normal conditions, Keap1 behaves as a negative regulator of NRF2, preventing its activation and thereby inhibiting its antioxidant response.

diagram

Figure 7

Diagram
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Source Paper

Curcumin Modulation of the Gut-Brain Axis for Neuroinflammation and Metabolic Disorders Prevention and Treatment.

Nutrients (2025)

PMID: 40362738

DOI: 10.3390/nu17091430

Cite This Figure

![Figure 7: Anti-inflammatory effects of curcumin: molecular and clinical evidence. Image shows the main mechanisms by which curcumin exerts anti-inflammatory effects both systemically and in adipocytes.](https://pdfs.citedhealth.com/figures/40362738/185.png)

> Source: Miriam Cerullo et al. "Curcumin Modulation of the Gut-Brain Axis for Neuroinflammation and Metabolic Di." *Nutrients*, 2025. PMID: [40362738](https://pubmed.ncbi.nlm.nih.gov/40362738/)
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  <img src="https://pdfs.citedhealth.com/figures/40362738/185.png" alt="Anti-inflammatory effects of curcumin: molecular and clinical evidence. Image shows the main mechanisms by which curcumin exerts anti-inflammatory effects both systemically and in adipocytes." />
  <figcaption>Figure 7. Anti-inflammatory effects of curcumin: molecular and clinical evidence. Image shows the main mechanisms by which curcumin exerts anti-inflammatory effects both systemically and in adipocytes.<br>  Source: Miriam Cerullo et al. "Curcumin Modulation of the Gut-Brain Axis for Neuroinflammation and Metabolic Di." <em>Nutrients</em>, 2025. PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/40362738/">40362738</a></figcaption>
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