Chemoprevention of prostate cancer.

Goutham Vemana, Robert J Hamilton, Gerald L Andriole, Stephen J Freedland

Review Annual review of medicine 2014 9 Zitierungen

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Study Design

Studientyp: review

Intervention: Chemoprevention of prostate cancer. None
Vergleichsgruppe: Placebo
Wirkungsrichtung: Mixed
Verzerrungsrisiko: Unclear

Abstract

Large prospective randomized trials, such as the Prostate Cancer Prevention Trial (PCPT), Reduction by Dutasteride of Prostate Cancer Events (REDUCE) trial, and Selenium and Vitamin E Cancer Prevention Trial (SELECT), have provided practitioners with considerable data regarding methods of treatment and prevention of prostate cancer. The best-studied medications for prevention are 5 alpha-reductase inhibitors. Their efficacy and side effects are well characterized. Other medications, dietary nutrients, and supplements have not been as well studied and generally do not demonstrate efficacy for disease prevention with an acceptable level of evidence.

Used In Evidence Reviews

B Vitamin E für Immune Aging (Immunosenescence)

C Selenium für Vaccine Response Support

Chemoprevention of prostate cancer.

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Study Design

Abstract

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