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ImmuneCited

Turkey Tail Mushroom per Immune Aging (Immunosenescence)

C

Phase I dose-escalation trial found 6-9 g/day of turkey tail extract significantly increased CD8+ T cells and CD19+ B cells. Approved as an adjunctive cancer therapy in Japan for decades, supporting its immunomodulatory profile.

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            C

        

        

            
In sintesi

            
            
Phase I dose-escalation trial found 6-9 g/day of turkey tail extract significantly increased CD8+ T cells and CD19+ B cells. Approved as an adjunctive cancer therapy in Japan for decades, supporting its immunomodulatory profile.

            
            
        

    










    

  
Key Study Findings





    

        
        

            

                
                    Review
                
                
                
                
            

            
                Anti-Cancer Potential of Edible/Medicinal Mushrooms in Breast Cancer.
            
            

                
                Dose: Edible/medicinal mushroom extracts
                
                
                vs: None
                
                
                Outcome: Anti-cancer activity in breast cancer
                
                
                Effetto: None
                
                
                None
                
            

            
            
Popolazione: Breast cancer (in vitro/animal review)

            
        

        
    







    
    

        
        

            

  
Key Statistics





            


    

        
3

        
Studi

    

    

        
100

        
Partecipanti

    

    

        
            
            ↑
            
        
        
Positive

    

    

        C

        
Grado

    




        


        
        
        

            

  
Referenced Papers





            

                
                

                    

                        
                            Anti-Cancer Potential of Edible/Medicinal Mushrooms in Breast Cancer.
                        
                        
                            
                                Review
                            
                            
                            
                        
                    

                    

                        International journal of …
                        2023
                        
                        40 citazioni
                        
                    

                

                
            

        

        

        
        
        

            

  
Dosage & Usage





            
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units


            
            

                
Dosaggi di uso comune

                

                    
                    

                        
general:

                        
1-3 g/day

                    

                    
                    

                        
clinical:

                        
3-9 g/day PSK/PSP extract

                    

                    
                

                
                

                    Limite massimo: No established UL
                

                
            

            

            
            

                
Dosaggi studiati nella ricerca

                

                    

                        
                            

                                Dosaggio
                                Durata
                                Effetto
                                N
                            

                        
                        
                            
                            

                                Edible/medicinal mushroom extracts
                                --
                                
                                    
                                    Positive
                                    
                                
                                --
                            

                            
                        
                    

                

            

            

            
            

                Momento migliore per l'assunzione: With or without food
            

            
        

        

        
        
        

            

  
Safety & Side Effects





            

                
                

                    
Effetti collaterali segnalati

                    
    
                        
                        
  • 
                            ⚠
                            Gastrointestinal symptoms (bloating, gas, dark stools)
                        
    • 
                        
                        
  • 
                            ⚠
                            Nail darkening (rare)
                        
    • 
                        
                        
  • 
                            ⚠
                            Allergic reactions (rare)
                        
    • 
                        
                    

                

                

                
                

                    
Interazioni note

                    
    
                        
                        
  • 
                            ●
                            Immunosuppressant medications (may counteract immunosuppression)
                        
    • 
                        
                        
  • 
                            ●
                            Cyclophosphamide (may enhance or modify effects)
                        
    • 
                        
                        
  • 
                            ●
                            Tamoxifen (theoretical interaction)
                        
    • 
                        
                    

                

                

                
                

                    

                        Livello di assunzione massimo tollerabile: No established UL
                    

                

                
            

            

                Consultare sempre il proprio medico prima di iniziare qualsiasi integratore.Consultate sempre il vostro medico prima di iniziare qualsiasi integratore.
            

        

        

        
        
        

            

  
Frequently Asked Questions





            




    
    

        
            Does Turkey Tail Mushroom help with Immune Aging (Immunosenescence)?
            
        
        

            Based on 3 studies with 100 participants, there is limited but promising evidence that Turkey Tail Mushroom may support Immune Aging (Immunosenescence) management. Our evidence grade is C (Some Evidence).
        

    

    
    

        
            How much Turkey Tail Mushroom should I take for Immune Aging (Immunosenescence)?
            
        
        

            Studies have used various dosages. A commonly studied range is 1-3 g/day. Always consult your healthcare provider before starting any supplement regimen.
        

    

    
    

        
            Are there side effects of Turkey Tail Mushroom?
            
        
        

            Reported side effects may include Gastrointestinal symptoms (bloating, gas, dark stools), Nail darkening (rare), Allergic reactions (rare). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
        

    

    
    

        
            How strong is the evidence for Turkey Tail Mushroom and Immune Aging (Immunosenescence)?
            
        
        

            We rate the evidence as Grade C (Some Evidence). This rating is based on 3 peer-reviewed studies with 100 total participants. The overall direction of effect is positive.
        

    

    




        

        

        
        
        

            

  
Related Evidence





            

                
                
                

                
            

        

        

    


    
    












    

        Avvertenza FDA:
        Queste affermazioni non sono state valutate dalla Food and Drug Administration. I prodotti e le informazioni presenti su questo sito web non sono destinati a diagnosticare, trattare, curare o prevenire alcuna malattia. I gradi di evidenza presentati si basano sulla nostra analisi della ricerca pubblicata e sottoposta a revisione paritaria e non costituiscono consulenza medica. Consultate sempre il vostro medico prima di iniziare qualsiasi regime di integrazione.