説明
Molecular mechanisms or therapeutic targets related to age-associated heart failure, covering topics such as senescent cell accumulation, RAAS dysregulation, and potential anti-aging interventions.
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Figure 1
Comprehensive diagram of cardiac aging mechanisms leading to heart failure, depicting how genomic, epigenetic, oxidative, autophagic, and inflammatory stresses drive structural changes including left ventricular hypertrophy and myocardial fibrosis.
diagram
Figure 2
Systemic aging pathways fueling heart failure, summarizing cardiac, vascular, metabolic, and inflammaging mechanisms alongside their associated molecular changes and clinical phenotypes.
diagram
Figure 3
Molecular mechanisms or therapeutic targets related to age-associated heart failure, covering topics such as senescent cell accumulation, RAAS dysregulation, and potential anti-aging interventions.
diagramFigure 4
DiagramSource Paper
Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues.Cite This Figure
 > Source: Zhuyubing Fang et al. "Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues." *ESC heart failure*, 2025. PMID: [39034866](https://pubmed.ncbi.nlm.nih.gov/39034866/)
<figure> <img src="https://pdfs.citedhealth.com/figures/39034866/207.png" alt="Molecular mechanisms or therapeutic targets related to age-associated heart failure, covering topics such as senescent cell accumulation, RAAS dysregulation, and potential anti-aging interventions." /> <figcaption>Figure 4. Molecular mechanisms or therapeutic targets related to age-associated heart failure, covering topics such as senescent cell accumulation, RAAS dysregulation, and potential anti-aging interventions.<br> Source: Zhuyubing Fang et al. "Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues." <em>ESC heart failure</em>, 2025. PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/39034866/">39034866</a></figcaption> </figure>