विवरण
Obesity, diabetes, and metabolic syndrome are illustrated as metabolic diseases that commonly coexist with depression, highlighting their shared pathophysiological mechanisms through chronic low-grade inflammation.
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Figure 3
Brain insulin resistance mechanisms underlying depression are depicted, showing how HPA axis dysregulation, reduced anterior cingulate cortex volume, and impaired hippocampal function contribute to the condition.
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Figure 5
Molecular pathways connecting stress-induced inflammation to insulin resistance are detailed, tracing how inflammatory signaling cascades impair insulin receptor substrate phosphorylation.
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Figure 6
Bidirectional relationships between depression and metabolic disturbances are outlined, showing how each condition exacerbates the other through shared inflammatory and neuroendocrine mechanisms.
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Figure 7
Treatment options for major depressive disorders are presented, including pharmacological, psychological, and lifestyle interventions that address the inflammatory-metabolic axis.
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Figure 8
A schematic representation maps the factors contributing to metabolic syndrome alongside corresponding dietary and lifestyle modifications that may alleviate these conditions, integrating evidence on stress management and anti-inflammatory nutrition.
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A review on linking stress, depression, and insulin resistance via low-grade chronic inflammation.Cite This Figure
 > Source: Seema Mehdi et al. "A review on linking stress, depression, and insulin resistance via low-grade chr." *Biochemistry and biophysics reports*, 2023. PMID: [37965066](https://pubmed.ncbi.nlm.nih.gov/37965066/)
<figure> <img src="https://pdfs.citedhealth.com/figures/37965066/125.png" alt="Obesity, diabetes, and metabolic syndrome are illustrated as metabolic diseases that commonly coexist with depression, highlighting their shared pathophysiological mechanisms through chronic low-grade inflammation." /> <figcaption>Figure 4. Obesity, diabetes, and metabolic syndrome are illustrated as metabolic diseases that commonly coexist with depression, highlighting their shared pathophysiological mechanisms through chronic low-grade inflammation.<br> Source: Seema Mehdi et al. "A review on linking stress, depression, and insulin resistance via low-grade chr." <em>Biochemistry and biophysics reports</em>, 2023. PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/37965066/">37965066</a></figcaption> </figure>