What is the recommended dosage for Cordyceps?

General: 1-3 g/day extract; Immune Support: 1,000-3,000 mg standardized extract/day

What are the side effects of Cordyceps?

Potential side effects include: Mild gastrointestinal discomfort, Dry mouth, Nausea (rare), Potential interaction with autoimmune conditions.

What is cordyceps and how does it support immune health?

Cordyceps is a genus of medicinal fungi traditionally used in Chinese medicine. The species C. sinensis and C. militaris contain cordycepin and polysaccharides that have been studied for their potential to modulate both innate and adaptive immune responses.

What dosage of cordyceps has been used in clinical studies?

Clinical trials have used cordyceps extract at doses of 1–3 g per day, typically as standardized Cs-4 mycelium or C. militaris fruiting body extract. Study durations range from 4 to 12 weeks for immune-related outcomes.

What are the potential side effects of cordyceps?

Cordyceps is generally well tolerated. Mild side effects may include gastrointestinal discomfort and dry mouth. It may interact with immunosuppressants and anticoagulant medications. People with autoimmune conditions should consult a doctor before use.

Cordyceps

mushroom

Also known as: Cordyceps militaris, Cordyceps sinensis, Caterpillar Fungus, Dong Chong Xia Cao

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About

Cordyceps contains cordycepin (3'-deoxyadenosine) and polysaccharides that enhance innate immune cascades, increase NK cell cytotoxicity, and modulate adaptive immunity. A double-blind RCT demonstrated 38.8% enhancement of NK cell cytotoxic activity after 8 weeks of supplementation in healthy adults.

How It Works

Cordycepin and polysaccharides enhance innate immune cascades, increase NK cell cytotoxicity, and modulate adaptive immunity; supports both immune activation in immunocompromised states and suppression of overactivated responses.

Evidence For Conditions

Condition	Grade	Studies	Participants
Immune Aging (Immunosenescence)	C	3	100	View →

Side Effects

Mild gastrointestinal discomfort
Dry mouth
Nausea (rare)
Potential interaction with autoimmune conditions

Drug & Supplement Interactions

Immunosuppressant medications (may counteract immunosuppression)
Anticoagulants (may increase bleeding risk)
Diabetes medications (may enhance blood sugar lowering)

Always inform your healthcare provider about all supplements you take.

Related Ingredients

Chaga Mushroom Maitake Mushroom Reishi Mushroom Turkey Tail Mushroom

Quick Facts

Dosage: General: 1-3 g/day extract; Immune_Support: 1,000-3,000 mg standardized extract/day
Forms: capsule powder liquid extract tincture
Natural Sources: Wild or cultivated fruiting body (supplement form only)
Upper Limit: No established UL
Best Time: Morning or early afternoon; with or without food

Evidence Summary

Immune Aging (Immunosenescence) C

FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. The products and information on this website are not intended to diagnose, treat, cure, or prevent any disease. The evidence grades presented are based on our analysis of published peer-reviewed research and do not constitute medical advice. Always consult your healthcare provider before starting any supplement regimen.