What is the recommended dosage for Vitamin B6?

General: 1.3-1.7 mg/day; Immune Support: 2-10 mg/day

What are the side effects of Vitamin B6?

Potential side effects include: Peripheral neuropathy at chronic doses >200 mg/day, Photosensitivity, Nausea, Decreased sensation in extremities (reversible upon cessation).

What is vitamin B6 and how does it relate to immune function?

Vitamin B6 (pyridoxine) is essential for over 100 enzymatic reactions, including those involved in immune cell metabolism and antibody production. Deficiency is associated with reduced lymphocyte proliferation and impaired interleukin-2 production.

What dosage of vitamin B6 has been studied for immune support?

The recommended dietary allowance is 1.3–1.7 mg per day for adults. Studies examining immune function have used doses of 2–50 mg per day. The Tolerable Upper Intake Level is 100 mg per day, above which peripheral neuropathy risk increases.

What are the potential side effects of vitamin B6 supplementation?

Vitamin B6 is generally safe at recommended doses. Chronic high-dose supplementation (above 200 mg per day) can cause peripheral neuropathy with symptoms including numbness and tingling in the hands and feet, which is usually reversible upon discontinuation.

Vitamin B6

vitamin

Also known as: Pyridoxine, Pyridoxal-5-Phosphate (P5P)

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About

Vitamin B6 supports lymphocyte maturation and differentiation, antibody production, and cytokine generation. It is critical for the biochemical reactions that regulate immune cell metabolism and inflammatory responses. Deficiency leads to decreased lymphocyte count and impaired antibody responses.

How It Works

Supports lymphocyte maturation and differentiation, antibody production, and cytokine generation; critical for biochemical reactions regulating immune cell metabolism.

Side Effects

Peripheral neuropathy at chronic doses >200 mg/day
Photosensitivity
Nausea
Decreased sensation in extremities (reversible upon cessation)

Drug & Supplement Interactions

Levodopa (reduces effectiveness; does not apply to carbidopa/levodopa combination)
Phenytoin and phenobarbital (mutual metabolism effects)
Isoniazid (depletes B6; supplementation recommended during TB treatment)

Always inform your healthcare provider about all supplements you take.

Related Ingredients

Vitamin A Vitamin C Vitamin D Vitamin E

Quick Facts

Dosage: General: 1.3-1.7 mg/day; Immune_Support: 2-10 mg/day
Forms: capsule tablet liquid
Natural Sources: Chickpeas, Poultry, Fish, Potatoes, Bananas, Fortified cereals
Upper Limit: 100 mg/day
Best Time: With meals

FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. The products and information on this website are not intended to diagnose, treat, cure, or prevent any disease. The evidence grades presented are based on our analysis of published peer-reviewed research and do not constitute medical advice. Always consult your healthcare provider before starting any supplement regimen.