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Fig. 4 Generation of oxidative stress by pollutant: role in allergic airway inflammation, Adapted from Li N. et al. J Allergy Clin Immunol. 2016, 138, 2: 366–396.35, ARE: Antioxidant response element; Nrf2: Nuclear Factor (erythroid derived 2) like 2, AP-1
Figure 4. Fig. 4 Generation of oxidative stress by pollutant: role in allergic airway inflammation, Adapted from Li N. et al. J Allergy Clin Immunol. 2016, 138, 2: 366–396.35, ARE: Antioxidant response element; Nrf2: Nuclear Factor (erythroid derived 2) like 2, AP-1: activator protein-1, NF-kB: Nuclear Factor–kappa beta, HO: Heme oxygenase, GST-ase: glutathione S transferase

説明

Air pollutants generate oxidative stress in the airway, driving allergic inflammation through the Nrf2 antioxidant response element pathway. This diagram illustrates how pollutant-induced reactive oxygen species activate the oxidative stress cascade, contributing to allergic airway disease.

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Figure 4

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Source Paper

International expert consensus on the management of allergic rhinitis (AR) aggravated by air pollutants: Impact of air pollution on patients …

The World Allergy Organization journal (2020)

PMID: 32256939

DOI: 10.1016/j.waojou.2020.100106

Cite This Figure

![Figure 4: Air pollutants generate oxidative stress in the airway, driving allergic inflammation through the Nrf2 antioxidant response element pathway. This diagram illustrates how pollutant-induced reactive oxygen species activate the oxidative stress cascade, contributing to allergic airway disease.](https://pdfs.citedhealth.com/figures/32256939/189.png)

> Source: Robert Naclerio et al. "International expert consensus on the management of allergic rhinitis (AR) aggra." *The World Allergy Organization journal*, 2020. PMID: [32256939](https://pubmed.ncbi.nlm.nih.gov/32256939/)
<figure>
  <img src="https://pdfs.citedhealth.com/figures/32256939/189.png" alt="Air pollutants generate oxidative stress in the airway, driving allergic inflammation through the Nrf2 antioxidant response element pathway. This diagram illustrates how pollutant-induced reactive oxygen species activate the oxidative stress cascade, contributing to allergic airway disease." />
  <figcaption>Figure 4. Air pollutants generate oxidative stress in the airway, driving allergic inflammation through the Nrf2 antioxidant response element pathway. This diagram illustrates how pollutant-induced reactive oxygen species activate the oxidative stress cascade, contributing to allergic airway disease.<br>  Source: Robert Naclerio et al. "International expert consensus on the management of allergic rhinitis (AR) aggra." <em>The World Allergy Organization journal</em>, 2020. PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/32256939/">32256939</a></figcaption>
</figure>

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