What is the recommended dosage for Curcumin?

General: 500-1,000 mg/day curcuminoids; Enhanced Absorption: 150-500 mg/day (phytosome or piperine formulation)

What are the side effects of Curcumin?

Potential side effects include: Gastrointestinal discomfort (nausea, diarrhea, bloating), Headache, Yellow stool discoloration, Iron absorption interference at very high doses.

What is curcumin and how does it relate to immune function?

Curcumin is the primary bioactive compound in turmeric (Curcuma longa). It has been extensively studied for its anti-inflammatory properties, including modulation of NF-kB signaling, cytokine regulation, and support of both innate and adaptive immune pathways.

What dosage of curcumin has been studied for immune support?

Clinical trials have used curcumin at doses of 500–2,000 mg per day, typically as enhanced-absorption formulations (piperine-combined, liposomal, or phytosome). Standard curcumin has poor bioavailability without an absorption enhancer.

What are the potential side effects of curcumin?

Curcumin is generally well tolerated at typical doses. High doses may cause gastrointestinal discomfort, nausea, or diarrhea. It may interact with blood thinners and anti-inflammatory medications. Individuals with gallbladder issues should consult a doctor.

Curcumin
Curcumin

antioxidant

다른 이름: Turmeric Extract, Curcuma longa, Diferuloylmethane

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About

Curcumin, the principal curcuminoid of turmeric, inhibits NF-kB, MAPK, and NLRP3 inflammasome activation while activating the Nrf2 antioxidant pathway. An umbrella meta-analysis of 5,870 participants across 10 studies demonstrated significant reduction in CRP, IL-6, and TNF-alpha inflammatory markers.

How It Works

Inhibits NF-kB, MAPK, and NLRP3 inflammasome activation; activates Nrf2 antioxidant pathway; modulates macrophage, dendritic cell, T-cell, B-cell, and NK cell function; suppresses COX-2 and pro-inflammatory cytokine production.

Evidence For Conditions

건강 상태	등급	연구	참여자
Chronic Inflammation	A	10	5870	보기 →

Side Effects

Gastrointestinal discomfort (nausea, diarrhea, bloating)
Headache
Yellow stool discoloration
Iron absorption interference at very high doses

Drug & Supplement Interactions

Anticoagulants and antiplatelet drugs (may increase bleeding risk)
Diabetes medications (may enhance blood sugar lowering)
CYP1A2, CYP3A4, CYP2D6 substrates (may inhibit metabolism)
Sulfasalazine and cyclophosphamide (may modify effects)

복용 중인 모든 건강기능식품에 대해 반드시 의료 전문가에게 알리십시오.

Related Ingredients

Quercetin Glutathione Astaxanthin Resveratrol

핵심 정보

용량: General: 500-1,000 mg/day curcuminoids; Enhanced_Absorption: 150-500 mg/day (phytosome or piperine formulation)
제형: capsule softgel powder liquid
천연 원료: Turmeric root (Curcuma longa)
상한 섭취량: No established UL; generally well-tolerated up to 8 g/day
권장 복용 시간: With meals containing fat and black pepper (piperine) for enhanced absorption

근거 요약

Chronic Inflammation A

FDA 면책 조항: 이 내용은 미국 식품의약국(FDA)의 평가를 받지 않았습니다. 이 웹사이트의 제품 및 정보는 질병의 진단, 치료, 완치 또는 예방을 목적으로 하지 않습니다. 제시된 근거 등급은 발표된 동료 심사 연구에 대한 우리의 분석에 기반하며, 의학적 조언을 구성하지 않습니다. 건강기능식품 복용을 시작하기 전에 반드시 의료 전문가와 상담하십시오.