CurcuminCurcumin
antioxidant
Curcumin
Curcumin
别名: Turmeric Extract, Curcuma longa, Diferuloylmethane
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About
姜黄的主要活性成分姜黄素抑制NF-κB、MAPK和NLRP3炎症体激活，同时激活Nrf2抗氧化通路。一项涵盖10项研究中5870名参与者的伞形荟萃分析证明了CRP、IL-6和TNF-α炎症标志物的显著降低。
How It Works
Inhibits NF-kB, MAPK, and NLRP3 inflammasome activation; activates Nrf2 antioxidant pathway; modulates macrophage, dendritic cell, T-cell, B-cell, and NK cell function; suppresses COX-2 and pro-inflammatory cytokine production.
Evidence For Conditions
| 健康状况 | 等级 | 研究数量 | 受试者 | |
|---|---|---|---|---|
| Chronic Inflammation | A | 10 | 5870 | 查看 → |
Side Effects
- Gastrointestinal discomfort (nausea, diarrhea, bloating)
- Headache
- Yellow stool discoloration
- Iron absorption interference at very high doses
Drug & Supplement Interactions
- Anticoagulants and antiplatelet drugs (may increase bleeding risk)
- Diabetes medications (may enhance blood sugar lowering)
- CYP1A2, CYP3A4, CYP2D6 substrates (may inhibit metabolism)
- Sulfasalazine and cyclophosphamide (may modify effects)
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Related Ingredients
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