What is the recommended dosage for Quercetin?

General: 500-1,000 mg/day; Immune Support: 500-1,500 mg/day

What are the side effects of Quercetin?

Potential side effects include: Headache, Tingling in extremities, Gastrointestinal discomfort, Low oral bioavailability (addressed by phytosome formulations).

What is quercetin and how does it support the immune system?

Quercetin is a flavonoid found in onions, apples, and berries. It has been studied for its antioxidant and anti-inflammatory properties, including its ability to inhibit pro-inflammatory cytokines and stabilize mast cells involved in allergic immune responses.

What dosage of quercetin has been studied for immune health?

Clinical trials have used quercetin at doses of 500–1,000 mg per day, often co-administered with vitamin C or bromelain to enhance absorption. Study durations range from 2 to 12 weeks depending on the outcome measured.

What are the potential side effects of quercetin?

Quercetin is generally well tolerated at doses up to 1,000 mg per day. High doses may cause headache, tingling, and gastrointestinal discomfort. Quercetin may interact with certain antibiotics and cyclosporine by affecting drug metabolism.

Quercetin
Quercetin

antioxidant

别名: Quercetin Dihydrate, Isoquercetin, Quercetin Phytosome

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About

Quercetin is a flavonol polyphenol with antioxidant, anti-inflammatory, and immunomodulatory properties. It inhibits mast cell degranulation and histamine release, modulates NF-kB and NLRP3 inflammasome pathways, and may act as a zinc ionophore to enhance intracellular zinc uptake. GRAS-designated by the FDA.

How It Works

Flavonol polyphenol that inhibits mast cell degranulation and histamine release; modulates NF-kB and NLRP3 inflammasome pathways; may support zinc ionophore activity to enhance intracellular zinc uptake.

Evidence For Conditions

健康状况	等级	研究数量	受试者
Allergic Rhinitis	C	5	400	查看 →

Side Effects

Headache
Tingling in extremities
Gastrointestinal discomfort
Low oral bioavailability (addressed by phytosome formulations)

Drug & Supplement Interactions

Cyclosporine (may increase drug levels)
Fluoroquinolone antibiotics (may interfere with bacterial target)
CYP3A4 and CYP2C8 substrates (may inhibit metabolism)

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Related Ingredients

Glutathione Astaxanthin Resveratrol Curcumin

速览

剂量: General: 500-1,000 mg/day; Immune_Support: 500-1,500 mg/day
剂型: capsule tablet powder
天然来源: Onions, Apples, Berries, Capers, Broccoli, Red wine, Green tea
上限: No established UL; GRAS up to 500 mg/day per FDA
最佳时间: With meals (fat-containing meals improve absorption); often paired with vitamin C or bromelain for enhanced bioavailability

证据摘要

Allergic Rhinitis C

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