ResveratrolResveratrol
antioxidant
Resveratrol
Resveratrol
别名: trans-Resveratrol
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About
Resveratrol is a polyphenol that modulates SIRT1 and AMPK signaling pathways, exhibits anti-inflammatory effects by inhibiting NF-kB, enhances macrophage function, and supports regulatory T-cell activity. Human trials show reduction in inflammatory markers, though low oral bioavailability remains a challenge.
How It Works
Modulates SIRT1 and AMPK signaling pathways; inhibits NF-kB; enhances macrophage function and supports regulatory T-cell activity; promotes immune homeostasis.
Evidence For Conditions
| 健康状况 | 等级 | 研究数量 | 受试者 | |
|---|---|---|---|---|
| Chronic Inflammation | C | 5 | 300 | 查看 → |
Side Effects
- Gastrointestinal discomfort (nausea, diarrhea)
- Headache
- Joint pain at very high doses (>2.5 g/day)
- Kidney issues at extremely high doses (case reports)
Drug & Supplement Interactions
- Anticoagulants and antiplatelet drugs (may increase bleeding risk)
- CYP1A2, CYP3A4 substrates (may inhibit metabolism)
- Estrogen-sensitive conditions (weak estrogenic activity)
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Related Ingredients
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