What is the recommended dosage for Resveratrol?

General: 150-500 mg/day; Immune Support: 250-500 mg/day trans-resveratrol

What are the side effects of Resveratrol?

Potential side effects include: Gastrointestinal discomfort (nausea, diarrhea), Headache, Joint pain at very high doses (>2.5 g/day), Kidney issues at extremely high doses (case reports).

What is resveratrol and how does it relate to immune health?

Resveratrol is a polyphenol found in grapes, red wine, and berries. It has been studied for its antioxidant and anti-inflammatory effects, including modulation of NF-kB and SIRT1 pathways that influence immune cell function and inflammatory responses.

What dosage of resveratrol has been studied in clinical trials?

Clinical studies have used resveratrol at doses of 150–2,000 mg per day. For immune and anti-inflammatory outcomes, doses of 250–500 mg per day of trans-resveratrol are commonly studied over periods of 4 to 12 weeks.

What are the potential side effects of resveratrol?

Resveratrol is generally well tolerated at moderate doses. Higher doses may cause gastrointestinal discomfort, nausea, and diarrhea. It may interact with blood thinners and medications metabolized by cytochrome P450 enzymes.

Resveratrol
Resveratrol

antioxidant

Também conhecido como: trans-Resveratrol

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About

Resveratrol is a polyphenol that modulates SIRT1 and AMPK signaling pathways, exhibits anti-inflammatory effects by inhibiting NF-kB, enhances macrophage function, and supports regulatory T-cell activity. Human trials show reduction in inflammatory markers, though low oral bioavailability remains a challenge.

How It Works

Modulates SIRT1 and AMPK signaling pathways; inhibits NF-kB; enhances macrophage function and supports regulatory T-cell activity; promotes immune homeostasis.

Evidence For Conditions

Condição	Nota	Estudos	Participantes
Chronic Inflammation	C	5	300	Ver →

Side Effects

Gastrointestinal discomfort (nausea, diarrhea)
Headache
Joint pain at very high doses (>2.5 g/day)
Kidney issues at extremely high doses (case reports)

Drug & Supplement Interactions

Anticoagulants and antiplatelet drugs (may increase bleeding risk)
CYP1A2, CYP3A4 substrates (may inhibit metabolism)
Estrogen-sensitive conditions (weak estrogenic activity)

Informe sempre o seu profissional de saúde sobre todos os suplementos que você toma.Sempre informe seu profissional de saúde sobre todos os suplementos que você toma.

Related Ingredients

Quercetin Glutathione Astaxanthin Curcumin

Dados Rápidos

Dosagem: General: 150-500 mg/day; Immune_Support: 250-500 mg/day trans-resveratrol
Formas: capsule softgel powder liquid
Fontes Naturais: Red grapes, Red wine, Blueberries, Peanuts, Dark chocolate
Limite Superior: No established UL; generally well-tolerated up to 1,500 mg/day
Melhor Horário: With meals

Resumo das Evidências

Chronic Inflammation C

Aviso Legal da FDA: Estas declarações não foram avaliadas pela Food and Drug Administration. Os produtos e informações neste site não se destinam a diagnosticar, tratar, curar ou prevenir qualquer doença. As notas de evidência apresentadas são baseadas em nossa análise de pesquisas revisadas por pares publicadas e não constituem aconselhamento médico. Sempre consulte seu profissional de saúde antes de iniciar qualquer regime de suplementação.