What is the recommended dosage for Maitake Mushroom?

General: 1-3 g/day; Md Fraction: 35-70 mg/day MD-Fraction extract

What are the side effects of Maitake Mushroom?

Potential side effects include: Generally well tolerated, Mild gastrointestinal effects at high doses, Potential hypoglycemia.

What is maitake and how does it support immune health?

Maitake (Grifola frondosa) is an edible mushroom containing D-fraction beta-glucans that have been studied for their potential to activate macrophages, dendritic cells, and natural killer cells. It is one of the more researched medicinal mushrooms for immune support.

What dosage of maitake has been used in clinical trials?

Studies have used maitake D-fraction extract at doses of 35–100 mg per day, or whole maitake powder at 3–7 g per day. Clinical data in humans remains limited compared to preclinical studies.

What are the potential side effects of maitake?

Maitake is generally well tolerated as a food and supplement. Mild gastrointestinal effects may occur. It may lower blood sugar and blood pressure, so individuals on diabetes or blood pressure medications should consult a healthcare provider.

Maitake Mushroom
Maitake Mushroom

mushroom

Também conhecido como: Grifola frondosa, Hen of the Woods, D-Fraction, MD-Fraction

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About

Maitake (Grifola frondosa) contains MD-Fraction (beta-1,6/1,3-glucan) that activates macrophages, dendritic cells, and NK cells via Dectin-1 and complement receptor 3. It enhances Th1 cytokine response while modulating Th2 response. Licensed as a cancer adjunctive treatment in Japan.

How It Works

MD-Fraction (beta-1,6/1,3-glucan) activates macrophages, dendritic cells, and NK cells via Dectin-1 and complement receptor 3; enhances Th1 cytokine response (IL-12, IFN-gamma) while modulating Th2 response.

Evidence For Conditions

Condição	Nota	Estudos	Participantes
Immune Aging (Immunosenescence)	C	3	100	Ver →

Side Effects

Generally well tolerated
Mild gastrointestinal effects at high doses
Potential hypoglycemia

Drug & Supplement Interactions

Diabetes medications (may lower blood sugar)
Anticoagulants (may increase bleeding risk)
Immunosuppressant medications (may counteract immunosuppression)

Informe sempre o seu profissional de saúde sobre todos os suplementos que você toma.Sempre informe seu profissional de saúde sobre todos os suplementos que você toma.

Related Ingredients

Reishi Mushroom Turkey Tail Mushroom Chaga Mushroom Cordyceps

Dados Rápidos

Dosagem: General: 1-3 g/day; Md_Fraction: 35-70 mg/day MD-Fraction extract
Formas: capsule powder liquid extract whole mushroom
Fontes Naturais: Wild or cultivated Grifola frondosa
Limite Superior: No established UL
Melhor Horário: With or without food

Resumo das Evidências

Immune Aging (Immunosenescence) C

Aviso Legal da FDA: Estas declarações não foram avaliadas pela Food and Drug Administration. Os produtos e informações neste site não se destinam a diagnosticar, tratar, curar ou prevenir qualquer doença. As notas de evidência apresentadas são baseadas em nossa análise de pesquisas revisadas por pares publicadas e não constituem aconselhamento médico. Sempre consulte seu profissional de saúde antes de iniciar qualquer regime de suplementação.