What is the recommended dosage for Maitake Mushroom?

General: 1-3 g/day; Md Fraction: 35-70 mg/day MD-Fraction extract

What are the side effects of Maitake Mushroom?

Potential side effects include: Generally well tolerated, Mild gastrointestinal effects at high doses, Potential hypoglycemia.

What is maitake and how does it support immune health?

Maitake (Grifola frondosa) is an edible mushroom containing D-fraction beta-glucans that have been studied for their potential to activate macrophages, dendritic cells, and natural killer cells. It is one of the more researched medicinal mushrooms for immune support.

What dosage of maitake has been used in clinical trials?

Studies have used maitake D-fraction extract at doses of 35–100 mg per day, or whole maitake powder at 3–7 g per day. Clinical data in humans remains limited compared to preclinical studies.

What are the potential side effects of maitake?

Maitake is generally well tolerated as a food and supplement. Mild gastrointestinal effects may occur. It may lower blood sugar and blood pressure, so individuals on diabetes or blood pressure medications should consult a healthcare provider.

Maitake Mushroom
Maitake Mushroom

mushroom

Juga dikenal sebagai: Grifola frondosa, Hen of the Woods, D-Fraction, MD-Fraction

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About

Maitake (Grifola frondosa) contains MD-Fraction (beta-1,6/1,3-glucan) that activates macrophages, dendritic cells, and NK cells via Dectin-1 and complement receptor 3. It enhances Th1 cytokine response while modulating Th2 response. Licensed as a cancer adjunctive treatment in Japan.

How It Works

MD-Fraction (beta-1,6/1,3-glucan) activates macrophages, dendritic cells, and NK cells via Dectin-1 and complement receptor 3; enhances Th1 cytokine response (IL-12, IFN-gamma) while modulating Th2 response.

Evidence For Conditions

Kondisi	Peringkat	Studi	Peserta
Immune Aging (Immunosenescence)	C	3	100	Lihat →

Side Effects

Generally well tolerated
Mild gastrointestinal effects at high doses
Potential hypoglycemia

Drug & Supplement Interactions

Diabetes medications (may lower blood sugar)
Anticoagulants (may increase bleeding risk)
Immunosuppressant medications (may counteract immunosuppression)

Selalu informasikan kepada tenaga kesehatan Anda tentang semua suplemen yang Anda konsumsi.Selalu informasikan penyedia layanan kesehatan Anda tentang semua suplemen yang Anda konsumsi.

Related Ingredients

Reishi Mushroom Turkey Tail Mushroom Cordyceps Chaga Mushroom

Fakta Singkat

Dosis: General: 1-3 g/day; Md_Fraction: 35-70 mg/day MD-Fraction extract
Bentuk Sediaan: capsule powder liquid extract whole mushroom
Sumber Alami: Wild or cultivated Grifola frondosa
Batas Atas: No established UL
Waktu Terbaik: With or without food

Ringkasan Bukti

Immune Aging (Immunosenescence) C

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