Maitake MushroomMaitake Mushroom
mushroom
别名: Grifola frondosa, Hen of the Woods, D-Fraction, MD-Fraction
About
Maitake (Grifola frondosa) contains MD-Fraction (beta-1,6/1,3-glucan) that activates macrophages, dendritic cells, and NK cells via Dectin-1 and complement receptor 3. It enhances Th1 cytokine response while modulating Th2 response. Licensed as a cancer adjunctive treatment in Japan.
How It Works
MD-Fraction (beta-1,6/1,3-glucan) activates macrophages, dendritic cells, and NK cells via Dectin-1 and complement receptor 3; enhances Th1 cytokine response (IL-12, IFN-gamma) while modulating Th2 response.
Evidence For Conditions
| 健康状况 | 等级 | 研究数量 | 受试者 | |
|---|---|---|---|---|
| Immune Aging (Immunosenescence) | C | 3 | 100 | 查看 → |
Side Effects
- Generally well tolerated
- Mild gastrointestinal effects at high doses
- Potential hypoglycemia
Drug & Supplement Interactions
- Diabetes medications (may lower blood sugar)
- Anticoagulants (may increase bleeding risk)
- Immunosuppressant medications (may counteract immunosuppression)
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Related Ingredients
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