Pelargonium sidoides 用于 Acute Bronchitis
AMeta-analyses demonstrate Pelargonium sidoides (EPs 7630) may significantly reduce bronchitis symptom severity and working inability. Approved as a medicine for respiratory infections in multiple countries. RCT showed working inability decreased to 16% vs 43% in placebo group after 7 days.
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A
结论
Meta-analyses demonstrate Pelargonium sidoides (EPs 7630) may significantly reduce bronchitis symptom severity and working inability. Approved as a medicine for respiratory infections in multiple countries. RCT showed working inability decreased to 16% vs 43% in placebo group after 7 days.
Key Study Findings
Other
Research Landscape and Emerging Trends in Herbal Medicine for Pediatric Respiratory Tract Infections: A CiteSpace-Based …
Dose: None
vs: None
Outcome: research landscape of herbal medicine for pediatric RTIs
效果: None
None
研究人群: pediatric patients with respiratory tract infections
Systematic Review
Pelargonium sidoides - from ethnopharmacology to evidence-based medicine: a systematic review.
Dose: None
vs: None
Outcome: clinical efficacy of Pelargonium sidoides for respiratory tract …
效果: None
None
研究人群: patients with acute bronchitis, rhinosinusitis, and tonsillopharyngitis
Randomized Controlled Trial
n=240
1 weeks
Double-blind
Efficacy and Safety of YJP-40 in Patients with Acute Bronchitis: A Randomized, Double-Blind, Parallel Group …
Dose: None
vs: Umckamin syrup (P. sidoides extract alone)
Outcome: Change in bronchitis severity score (BSS) at day …
效果: BSS change: -4.31 vs -4.36
non-inferiority demonstrated
研究人群: Patients with acute bronchitis from 7 hospitals
Randomized Controlled Trial
1 weeks
Double-blind
Efficacy and safety of mixture of ivy leaf extract and coptidis rhizome in the treatment …
Dose: Ivy leaf extract + Coptidis rhizome
vs: Pelargonium sidoides extract
Outcome: Bronchitis severity score (BSS)
效果: None
None
研究人群: Adults with acute bronchitis
Review
Chronobiological Efficacy of Combined Therapy of Pelargonium Sidoides and Melatonin in Acute and Persistent Cases …
Dose: None
vs: None
Outcome: inflammation markers
效果: None
None
研究人群: Covid-19
Randomized Controlled Trial
n=591
1.0 weeks
Open-label
Safety of Pelargonium extract EPs 7630 in young children with acute bronchitis.
Dose: 7.2%
vs: None
Outcome: None
效果: None
None
研究人群: Ab received eps 7630 syrup or solution for 7 days
Key Statistics
8
研究数量
2000
受试者
↑
Positive
A
等级
Referenced Papers
Health science reports
2026
Pelargonium sidoides - from ethnopharmacology to evidence-based medicine: a systematic review.
Systematic Review
Phytomedicine : international …
2026
Tuberculosis and respiratory …
2025
Current medical research …
2024
2 次引用
Frontiers in pediatrics
2023
7 次引用
Effects of EPs 7630 on the duration of inability to work in acute bronchitis - a meta-analysis.
Other
Multidisciplinary respiratory medicine
2023
4 次引用
Advances in experimental …
2023
2 次引用
Phytochemical analysis : …
2022
14 次引用
Multidisciplinary respiratory medicine
2022
13 次引用
The Korean journal …
2022
3 次引用
BMC complementary medicine …
2021
16 次引用
Complementary and alternative medicine in the treatment of acute bronchitis in children: A systematic review.
Systematic Review
Complementary therapies in …
2020
36 次引用
PloS one
2019
50 次引用
Faster recovery and reduced paracetamol use - a meta-analysis of EPs 7630 in children with acute respiratory tract infections.
Meta-Analysis
BMC pediatrics
2019
27 次引用
Integrative medicine (Encinitas, …
2019
17 次引用
Pilot and feasibility …
2019
8 次引用
International journal of …
2018
55 次引用
Current medical research …
2018
28 次引用
Phytomedicine : international …
2015
35 次引用
Planta medica
2015
9 次引用
The Cochrane database …
2013
125 次引用
Current medical research …
2013
25 次引用
Antiviral research
2012
107 次引用
Pediatrics international : …
2012
56 次引用
Annals of hepatology
2012
Holistic nursing practice
2012
Phytomedicine : international …
2011
139 次引用
International journal of …
2010
64 次引用
Acta paediatrica (Oslo, …
2010
63 次引用
Current medical research …
2010
54 次引用
Wiener medizinische Wochenschrift …
2010
6 次引用
Journal of ethnopharmacology
2008
165 次引用
Phytomedicine : international …
2008
100 次引用
Pelargonium sidoides extract for acute respiratory tract infections.
Systematic Review
The Cochrane database …
2008
71 次引用
Planta medica
2008
40 次引用
Current medical research …
2007
81 次引用
Phytomedicine : international …
2007
71 次引用
Phytomedicine : international …
2007
54 次引用
Phytomedicine : international …
2007
39 次引用
Wiener medizinische Wochenschrift …
2007
23 次引用
Phytomedicine : international …
2007
12 次引用
Explore (New York, …
2005
100 次引用
Phytomedicine : international …
2003
104 次引用
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
常用剂量
- general:
- 30 drops (1.5 mL) liquid extract 3x/day or 20 mg EPs 7630 tablets 3x/day
- duration:
- 7-14 days
上限： No established UL
研究中使用的剂量
| 剂量 | 持续时间 | 效果 | N |
|---|---|---|---|
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| None | 1 weeks | Neutral | 240 |
| Ivy leaf extract + Coptidis rhizome | 1 weeks | Positive | -- |
| None | -- | Mixed | -- |
| 7.2% | 1.0 weeks | Positive | 591 |
| 83.6% | 10.4 weeks | Mixed | 505 |
| None | -- | Positive | 2195 |
最佳服用时间： At onset of respiratory symptoms; 3x daily for up to 14 days
Safety & Side Effects
已报告的副作用
- ⚠ Gastrointestinal discomfort (rare)
- ⚠ Allergic skin reactions (rare)
- ⚠ Nosebleeds (rare)
- ⚠ Hepatotoxicity (very rare, case reports)
已知相互作用
- ● Anticoagulants (theoretical increased bleeding risk due to coumarin content)
- ● Immunosuppressant medications (may modulate immune function)
可耐受最高摄入量： No established UL
在开始服用任何补充剂之前，请务必咨询您的医疗保健提供者。
Frequently Asked Questions
Does Pelargonium sidoides help with Acute Bronchitis?
Based on 8 studies with 2,000 participants, there is strong evidence from multiple clinical trials that Pelargonium sidoides may support Acute Bronchitis management. Our evidence grade is A (Strong Evidence).
How much Pelargonium sidoides should I take for Acute Bronchitis?
Studies have used various dosages. A commonly studied range is 30 drops (1.5 mL) liquid extract 3x/day or 20 mg EPs 7630 tablets 3x/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Pelargonium sidoides?
Reported side effects may include Gastrointestinal discomfort (rare), Allergic skin reactions (rare), Nosebleeds (rare), Hepatotoxicity (very rare, case reports). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Pelargonium sidoides and Acute Bronchitis?
We rate the evidence as Grade A (Strong Evidence). This rating is based on 8 peer-reviewed studies with 2,000 total participants. The overall direction of effect is positive.
Related Evidence
其他成分用于 Acute Bronchitis
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