Cordyceps لـ Immune Aging (Immunosenescence)

Q: Does Cordyceps help with Immune Aging (Immunosenescence)?

Based on 3 studies with 100 participants, there is limited but promising evidence that Cordyceps may support Immune Aging (Immunosenescence) management. Our evidence grade is C (Some Evidence).

Q: How much Cordyceps should I take for Immune Aging (Immunosenescence)?

Studies have used various dosages. A commonly studied range is 1-3 g/day extract. Always consult your healthcare provider before starting any supplement regimen.

Q: Are there side effects of Cordyceps?

Reported side effects may include Mild gastrointestinal discomfort, Dry mouth, Nausea (rare), Potential interaction with autoimmune conditions. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

Q: How strong is the evidence for Cordyceps and Immune Aging (Immunosenescence)?

We rate the evidence as Grade C (Some Evidence). This rating is based on 3 peer-reviewed studies with 100 total participants. The overall direction of effect is positive.

A double-blind randomized controlled trial found Cordyceps mycelium extract showed 38.8% enhancement of NK cell cytotoxic activity after 8 weeks in healthy adults. Supports cell-mediated immunity and may enhance immune surveillance capacity.

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الخلاصة

Key Study Findings

Review n=321

Current Evidence of Ergogenic and Post-Exercise Recovery Effects of Dietary Supplementation with Cordyceps militaris in …

Dose: None مقابل: None Outcome: None التأثير: None None

المجتمع المدروس: healthy individuals aged 16-35 from 5 intervention studies (2017-2024)

Other

The Inhibitory Effects of Cordyceps militaris ARA301 Extract on Lipopolysaccharide-Induced Lung Injury in vivo.

Dose: None مقابل: LPS-induced lung injury mouse model vs control Outcome: Immune cell infiltration and inflammatory cytokines التأثير: None None

المجتمع المدروس: LPS-induced lung injury mouse model

Controlled Clinical Trial n=24 3 weeks

Cordyceps militaris extract and cordycepin ameliorate LPS-challenged colonic damage in piglets by modulating the microbiota …

Dose: 60 mg/kg in basal diet مقابل: LPS-challenged control (basal diet only) Outcome: Colonic morphology and microbiota composition التأثير: None None

المجتمع المدروس: Weaned castrated piglets challenged with LPS

Review

Ergogenic Aid by Cordyceps: Does It Work??

Dose: None مقابل: None Outcome: None التأثير: None None

المجتمع المدروس: Review of Cordyceps as ergogenic aid in human studies

In Vitro n=24

Transcriptomic and Metabolomic Analyses Reveal the Attenuating Role of Cordycepin and Cordyceps militaris Extract on …

Dose: Cordycepin (CPN) or C. militaris extract (CME) مقابل: Basal diet + LPS challenge Outcome: Liver injury markers and transcriptome changes التأثير: None None

المجتمع المدروس: Weaned piglets (4 groups, n=6)

Randomized Controlled Trial 2 weeks Double-blind

Beet supplementation mitigates post-exercise inflammation.

Dose: 212 mg مقابل: Placebo Outcome: Inflammatory markers التأثير: None p < 0.001

المجتمع المدروس: None

Key Statistics

الدراسات

100

المشاركون

↑

Positive

التقييم

Referenced Papers

Current Evidence of Ergogenic and Post-Exercise Recovery Effects of Dietary Supplementation with Cordyceps militaris in Humans-A Narrative Review. Review

Nutrients 2026

The Inhibitory Effects of Cordyceps militaris ARA301 Extract on Lipopolysaccharide-Induced Lung Injury in vivo. Other

Journal of microbiology … 2025 2 اقتباسات

Ergogenic Aid by Cordyceps: Does It Work?? Review

Current nutrition reports 2025 2 اقتباسات

Cordyceps militaris extract and cordycepin ameliorate LPS-challenged colonic damage in piglets by modulating the microbiota and metabolite profiles. Other

Frontiers in immunology 2025 1 اقتباسات

Beet supplementation mitigates post-exercise inflammation. Other

Frontiers in nutrition 2024 8 اقتباسات

Synergistic fermentation of Cordyceps militaris and herbal substrates boosts grower pig antioxidant and immune function. Other

BMC veterinary research 2024 7 اقتباسات

Transcriptomic and Metabolomic Analyses Reveal the Attenuating Role of Cordycepin and Cordyceps militaris Extract on Acute Liver Injury Induced by … Other

Animals : an … 2024 1 اقتباسات

Anti-Cancer Potential of Edible/Medicinal Mushrooms in Breast Cancer. Review

International journal of … 2023 40 اقتباسات

Exploring Edible Mushrooms for Diabetes: Unveiling Their Role in Prevention and Treatment. Review

Molecules (Basel, Switzerland) 2023 40 اقتباسات

Medicinal Mushroom Supplements in Cancer: A Systematic Review of Clinical Studies. Systematic Review

Current oncology reports 2023 27 اقتباسات

Cordyceps militaris extracts and cordycepin ameliorate type 2 diabetes mellitus by modulating the gut microbiota and metabolites. Other

Frontiers in pharmacology 2023 26 اقتباسات

Early Trends to Show the Efficacy of Cordyceps militaris in Mild to Moderate COVID Inflammation. Other

Cureus 2023 5 اقتباسات

A Comprehensive Review of Herbal Supplements Used for Persistent Symptoms Attributed to Lyme Disease. Review

Integrative medicine (Encinitas, … 2023 2 اقتباسات

Medicinal Fungi with Antiviral Effect. Review

Molecules (Basel, Switzerland) 2022 34 اقتباسات

Integrative medicine considerations for convalescence from mild-to-moderate COVID-19 disease. Review

Explore (New York, … 2022 34 اقتباسات

Cordycepin for Health and Wellbeing: A Potent Bioactive Metabolite of an Entomopathogenic Cordyceps Medicinal Fungus and Its Nutraceutical and Therapeutic … Review

Molecules (Basel, Switzerland) 2020 153 اقتباسات

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

الجرعات الشائعة

general:: 1-3 g/day extract
immunesupport:: 1,000-3,000 mg standardized extract/day

الحد الأعلى: No established UL

الجرعات المدروسة في الأبحاث

الجرعة	المدة	التأثير	ن
None	--	Mixed	321
None	--	Positive	--
60 mg/kg in basal diet	3 weeks	Positive	24
None	--	Mixed	--
Cordycepin (CPN) or C. militaris extract (CME)	--	Positive	24
212 mg	2 weeks	Neutral	--
None	--	Positive	--
Mushroom extracts (various species)	--	Positive	--

أفضل وقت للتناول: Morning or early afternoon; with or without food

Safety & Side Effects

الآثار الجانبية المُبلّغ عنها

⚠ Mild gastrointestinal discomfort
⚠ Dry mouth
⚠ Nausea (rare)
⚠ Potential interaction with autoimmune conditions

التفاعلات المعروفة

● Immunosuppressant medications (may counteract immunosuppression)
● Anticoagulants (may increase bleeding risk)
● Diabetes medications (may enhance blood sugar lowering)

الحد الأقصى المسموح به: No established UL

استشر مقدم الرعاية الصحية دائماً قبل البدء بأي مكمل غذائي.

Frequently Asked Questions

Does Cordyceps help with Immune Aging (Immunosenescence)?

Based on 3 studies with 100 participants, there is limited but promising evidence that Cordyceps may support Immune Aging (Immunosenescence) management. Our evidence grade is C (Some Evidence).

How much Cordyceps should I take for Immune Aging (Immunosenescence)?

Studies have used various dosages. A commonly studied range is 1-3 g/day extract. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Cordyceps?

Reported side effects may include Mild gastrointestinal discomfort, Dry mouth, Nausea (rare), Potential interaction with autoimmune conditions. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Cordyceps and Immune Aging (Immunosenescence)?

We rate the evidence as Grade C (Some Evidence). This rating is based on 3 peer-reviewed studies with 100 total participants. The overall direction of effect is positive.

Related Evidence

مكونات أخرى لـ Immune Aging (Immunosenescence)

Vitamin D B Vitamin E B Bifidobacterium lactis B Reishi Mushroom C Turkey Tail Mushroom C Maitake Mushroom C

الخلاصة السريعة

Evidence Strength52%

Moderate confidence

تفصيل الدراسات

RCT (0)Meta (0)Other (3)

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اعرف المزيد

إخلاء مسؤولية FDA: لم تُقيَّم هذه البيانات من قبل إدارة الغذاء والدواء (FDA). لا تهدف المنتجات والمعلومات الواردة في هذا الموقع إلى تشخيص أو علاج أو شفاء أو الوقاية من أي مرض. تستند تقييمات الأدلة المعروضة إلى تحليلنا للأبحاث المحكّمة المنشورة ولا تُشكّل نصيحة طبية. استشر مقدم الرعاية الصحية دائماً قبل البدء بأي نظام مكملات.