Cordyceps के लिए Immune Aging (Immunosenescence)
C साक्ष्य की तुलना करें छोटे अध्ययनों से सीमित साक्ष्य उपलब्ध हैं, लेकिन कुछ सकारात्मक संकेत मौजूद हैं।A double-blind randomized controlled trial found Cordyceps mycelium extract showed 38.8% enhancement of NK cell cytotoxic activity after 8 weeks in healthy adults. Supports cell-mediated immunity and may enhance immune surveillance capacity.
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C
निष्कर्ष
A double-blind randomized controlled trial found Cordyceps mycelium extract showed 38.8% enhancement of NK cell cytotoxic activity after 8 weeks in healthy adults. Supports cell-mediated immunity and may enhance immune surveillance capacity.
Key Study Findings
Review
n=321
Current Evidence of Ergogenic and Post-Exercise Recovery Effects of Dietary Supplementation with Cordyceps militaris in …
Dose: None
बनाम: None
Outcome: None
प्रभाव: None
None
जनसंख्या: healthy individuals aged 16-35 from 5 intervention studies (2017-2024)
Other
The Inhibitory Effects of Cordyceps militaris ARA301 Extract on Lipopolysaccharide-Induced Lung Injury in vivo.
Dose: None
बनाम: LPS-induced lung injury mouse model vs control
Outcome: Immune cell infiltration and inflammatory cytokines
प्रभाव: None
None
जनसंख्या: LPS-induced lung injury mouse model
Controlled Clinical Trial
n=24
3 weeks
Cordyceps militaris extract and cordycepin ameliorate LPS-challenged colonic damage in piglets by modulating the microbiota …
Dose: 60 mg/kg in basal diet
बनाम: LPS-challenged control (basal diet only)
Outcome: Colonic morphology and microbiota composition
प्रभाव: None
None
जनसंख्या: Weaned castrated piglets challenged with LPS
Review
Ergogenic Aid by Cordyceps: Does It Work??
Dose: None
बनाम: None
Outcome: None
प्रभाव: None
None
जनसंख्या: Review of Cordyceps as ergogenic aid in human studies
In Vitro
n=24
Transcriptomic and Metabolomic Analyses Reveal the Attenuating Role of Cordycepin and Cordyceps militaris Extract on …
Dose: Cordycepin (CPN) or C. militaris extract (CME)
बनाम: Basal diet + LPS challenge
Outcome: Liver injury markers and transcriptome changes
प्रभाव: None
None
जनसंख्या: Weaned piglets (4 groups, n=6)
Randomized Controlled Trial
2 weeks
Double-blind
Beet supplementation mitigates post-exercise inflammation.
Dose: 212 mg
बनाम: Placebo
Outcome: Inflammatory markers
प्रभाव: None
p < 0.001
जनसंख्या: None
Key Statistics
3
अध्ययन
100
प्रतिभागी
↑
Positive
C
ग्रेड
Referenced Papers
Nutrients
2026
Journal of microbiology …
2025
2 उद्धरण
Current nutrition reports
2025
2 उद्धरण
Frontiers in immunology
2025
1 उद्धरण
Frontiers in nutrition
2024
8 उद्धरण
BMC veterinary research
2024
7 उद्धरण
Animals : an …
2024
1 उद्धरण
International journal of …
2023
40 उद्धरण
Molecules (Basel, Switzerland)
2023
40 उद्धरण
Medicinal Mushroom Supplements in Cancer: A Systematic Review of Clinical Studies.
Systematic Review
Current oncology reports
2023
27 उद्धरण
Frontiers in pharmacology
2023
26 उद्धरण
Early Trends to Show the Efficacy of Cordyceps militaris in Mild to Moderate COVID Inflammation.
Other
Cureus
2023
5 उद्धरण
Integrative medicine (Encinitas, …
2023
2 उद्धरण
Molecules (Basel, Switzerland)
2022
34 उद्धरण
Integrative medicine considerations for convalescence from mild-to-moderate COVID-19 disease.
Review
Explore (New York, …
2022
34 उद्धरण
Molecules (Basel, Switzerland)
2020
153 उद्धरण
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
सामान्य रूप से उपयोग की जाने वाली खुराकें
- general:
- 1-3 g/day extract
- immunesupport:
- 1,000-3,000 mg standardized extract/day
अधिकतम सीमा: No established UL
अनुसंधान में अध्ययन की गई खुराकें
| खुराक | अवधि | प्रभाव | N |
|---|---|---|---|
| None | -- | Mixed | 321 |
| None | -- | Positive | -- |
| 60 mg/kg in basal diet | 3 weeks | Positive | 24 |
| None | -- | Mixed | -- |
| Cordycepin (CPN) or C. militaris extract (CME) | -- | Positive | 24 |
| 212 mg | 2 weeks | Neutral | -- |
| None | -- | Positive | -- |
| Mushroom extracts (various species) | -- | Positive | -- |
सेवन का सर्वोत्तम समय: Morning or early afternoon; with or without food
Safety & Side Effects
रिपोर्ट किए गए दुष्प्रभाव
- ⚠ Mild gastrointestinal discomfort
- ⚠ Dry mouth
- ⚠ Nausea (rare)
- ⚠ Potential interaction with autoimmune conditions
ज्ञात अंतःक्रियाएँ
- ● Immunosuppressant medications (may counteract immunosuppression)
- ● Anticoagulants (may increase bleeding risk)
- ● Diabetes medications (may enhance blood sugar lowering)
सहनीय अधिकतम सेवन: No established UL
कोई भी सप्लीमेंट शुरू करने से पहले हमेशा अपने स्वास्थ्य सेवा प्रदाता से परामर्श करें।
Frequently Asked Questions
Does Cordyceps help with Immune Aging (Immunosenescence)?
Based on 3 studies with 100 participants, there is limited but promising evidence that Cordyceps may support Immune Aging (Immunosenescence) management. Our evidence grade is C (Some Evidence).
How much Cordyceps should I take for Immune Aging (Immunosenescence)?
Studies have used various dosages. A commonly studied range is 1-3 g/day extract. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Cordyceps?
Reported side effects may include Mild gastrointestinal discomfort, Dry mouth, Nausea (rare), Potential interaction with autoimmune conditions. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Cordyceps and Immune Aging (Immunosenescence)?
We rate the evidence as Grade C (Some Evidence). This rating is based on 3 peer-reviewed studies with 100 total participants. The overall direction of effect is positive.
Related Evidence
इसके लिए अन्य सामग्री Immune Aging (Immunosenescence)
References
- [1] Maciej Jędrejko et al.. Nutrients. 2026. Current Evidence of Ergogenic and Post-Exercise Recovery Effects of Dietary Supplementation with Cordyceps militaris in Humans-A Narrative Review. doi:10.3390/nu18050781 PubMed
- [2] Hye Kang Seong et al.. J Microbiol Biotechnol. 2025. The Inhibitory Effects of Cordyceps militaris ARA301 Extract on Lipopolysaccharide-Induced Lung Injury in vivo. doi:10.4014/jmb.2412.12043 PubMed
- [3] Luthfia Dewi et al.. Curr Nutr Rep. 2025. Ergogenic Aid by Cordyceps: Does It Work?? doi:10.1007/s13668-025-00690-9 PubMed
- [4] Shijie Xiong et al.. Front Immunol. 2025. Cordyceps militaris extract and cordycepin ameliorate LPS-challenged colonic damage in piglets by modulating the microbiota and metabolite profiles. doi:10.3389/fimmu.2025.1530098 PubMed
- [5] David C Nieman et al.. Front Nutr. 2024. Beet supplementation mitigates post-exercise inflammation. doi:10.3389/fnut.2024.1408804 PubMed
- [6] Chia-Chen Pi et al.. BMC Vet Res. 2024. Synergistic fermentation of Cordyceps militaris and herbal substrates boosts grower pig antioxidant and immune function. doi:10.1186/s12917-024-04338-8 PubMed
- [7] Ding Tan et al.. Animals (Basel). 2024. Transcriptomic and Metabolomic Analyses Reveal the Attenuating Role of Cordycepin and Cordyceps militaris Extract on Acute Liver Injury Induced by … doi:10.3390/ani14192873 PubMed
- [8] Marzia Bruna Gariboldi et al.. Int J Mol Sci. 2023. Anti-Cancer Potential of Edible/Medicinal Mushrooms in Breast Cancer. doi:10.3390/ijms241210120 PubMed
- [9] Mohammad Zaki Shamim et al.. Molecules. 2023. Exploring Edible Mushrooms for Diabetes: Unveiling Their Role in Prevention and Treatment. doi:10.3390/molecules28062837 PubMed
- [10] Santhosshi Narayanan et al.. Curr Oncol Rep. 2023. Medicinal Mushroom Supplements in Cancer: A Systematic Review of Clinical Studies. doi:10.1007/s11912-023-01408-2 PubMed
- [11] Xinyuan Liu et al.. Front Pharmacol. 2023. Cordyceps militaris extracts and cordycepin ameliorate type 2 diabetes mellitus by modulating the gut microbiota and metabolites. doi:10.3389/fphar.2023.1134429 PubMed
- [12] Siddharth Dubhashi et al.. Cureus. 2023. Early Trends to Show the Efficacy of Cordyceps militaris in Mild to Moderate COVID Inflammation. doi:10.7759/cureus.43731 PubMed
- [13] Allison Thompson et al.. Integr Med (Encinitas). 2023. A Comprehensive Review of Herbal Supplements Used for Persistent Symptoms Attributed to Lyme Disease. PubMed
- [14] Yu Zhang et al.. Molecules. 2022. Medicinal Fungi with Antiviral Effect. doi:10.3390/molecules27144457 PubMed
- [15] Lise Alschuler et al.. Explore (NY). 2022. Integrative medicine considerations for convalescence from mild-to-moderate COVID-19 disease. doi:10.1016/j.explore.2020.12.005 PubMed
- [16] Syed Amir Ashraf et al.. Molecules. 2020. Cordycepin for Health and Wellbeing: A Potent Bioactive Metabolite of an Entomopathogenic Cordyceps Medicinal Fungus and Its Nutraceutical and Therapeutic … doi:10.3390/molecules25122735 PubMed
FDA अस्वीकरण: इन कथनों का Food and Drug Administration द्वारा मूल्यांकन नहीं किया गया है। इस वेबसाइट पर उत्पादों और जानकारी का उद्देश्य किसी बीमारी का निदान, उपचार, इलाज या रोकथाम नहीं है। प्रस्तुत साक्ष्य ग्रेड प्रकाशित पीयर-रिव्यूड अनुसंधान के हमारे विश्लेषण पर आधारित हैं और चिकित्सा सलाह नहीं हैं। कोई भी सप्लीमेंट शुरू करने से पहले हमेशा अपने स्वास्थ्य सेवा प्रदाता से परामर्श करें।