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ImmuneCited

Astragalus for Allergic Rhinitis

C

A clinical trial found astragalus at 160 mg twice daily may help reduce sneezing and runny nose symptoms in seasonal allergy sufferers. Traditionally used in Chinese medicine as a preventive immune tonic for over 2,000 years.

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The Bottom Line

A clinical trial found astragalus at 160 mg twice daily may help reduce sneezing and runny nose symptoms in seasonal allergy sufferers. Traditionally used in Chinese medicine as a preventive immune tonic for over 2,000 years.

Key Study Findings

Review
Rebalancing the inflammatory niche in allergic rhinitis ".
Dose: None vs: None Outcome: ILC2 suppression and mucosal homeostasis in allergic rhinitis Effect: None None

Population: patients with allergic rhinitis (preclinical and some human data)

Review
Traditional Chinese Medicine for Allergic Rhinitis: Mechanisms, Evidence, and Gut-Immune Axis Targets.
Dose: None vs: None Outcome: TCM effects on allergic rhinitis via gut microbiota … Effect: None None

Population: patients with allergic rhinitis (human and animal models)

Other
Network pharmacology analysis of the Huangqi-Gancao herb pair reveals quercetin as a therapeutics for allergic …
Dose: None vs: OVA-induced AR mice without treatment Outcome: Allergic rhinitis symptoms and histopathology Effect: None None

Population: OVA-induced allergic rhinitis mouse model

In Vitro
Identification of Active Markers of Chinese Formula Yupingfeng San by Network Pharmacology and HPLC-Q-TOF-MS/MS Analysis …
Dose: None vs: Allergic rhinitis mouse model vs control Outcome: Nasal mucosal inflammation and serum markers Effect: None None

Population: Allergic rhinitis mouse model

Other
A research method of compatibility mechanism of traditional Chinese medicine prescription-taking Yupingfeng San as an …
Dose: None vs: Reduced component groups Outcome: IL-2, IL-4, IGE, TGF-beta levels Effect: None None

Population: Allergic rhinitis mouse model

Other
Astragalus polysaccharide alleviates IL-13-induced oxidative stress injury in nasal epithelial cells by inhibiting WTAP-mediated FBXW7 …
Dose: None vs: None Outcome: Oxidative stress markers Effect: None None

Population: None

Key Statistics

3

Studies

200

Participants

Positive

C

Grade

Referenced Papers

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Commonly Used Dosages

general:
250-500 mg standardized extract/day
traditional:
9-30 g dried root decoction/day

Upper limit: No established UL

Dosages Studied in Research

Dosage Duration Effect N
None -- Positive --
None -- Positive --
None -- Positive --
None -- Positive --
None -- Positive --
None -- Positive --
None -- Positive --
None -- Positive --

Best taken: With meals; traditionally used as a preventive tonic (not during acute illness)

Safety & Side Effects

Reported Side Effects

  • Generally well tolerated
  • Mild gastrointestinal effects (bloating, diarrhea) at high doses
  • Possible interaction with autoimmune conditions (immunostimulatory)

Known Interactions

  • Immunosuppressant medications (may counteract immunosuppression)
  • Lithium (may reduce lithium excretion)
  • Cyclophosphamide (may enhance or interfere with effects)

Tolerable upper intake: No established UL

Always consult your healthcare provider before starting any supplement.

Frequently Asked Questions

Does Astragalus help with Allergic Rhinitis?
Based on 3 studies with 200 participants, there is limited but promising evidence that Astragalus may support Allergic Rhinitis management. Our evidence grade is C (Some Evidence).
How much Astragalus should I take for Allergic Rhinitis?
Studies have used various dosages. A commonly studied range is 250-500 mg standardized extract/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Astragalus?
Reported side effects may include Generally well tolerated, Mild gastrointestinal effects (bloating, diarrhea) at high doses, Possible interaction with autoimmune conditions (immunostimulatory). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Astragalus and Allergic Rhinitis?
We rate the evidence as Grade C (Some Evidence). This rating is based on 3 peer-reviewed studies with 200 total participants. The overall direction of effect is positive.

Related Evidence

Other ingredients for Allergic Rhinitis

FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. The products and information on this website are not intended to diagnose, treat, cure, or prevent any disease. The evidence grades presented are based on our analysis of published peer-reviewed research and do not constitute medical advice. Always consult your healthcare provider before starting any supplement regimen.