Astragalus 用于 过敏性鼻炎
C 证据 来自小型研究的证据有限，但存在一些积极信号。A clinical trial found astragalus at 160 mg twice daily may help reduce sneezing and runny nose symptoms in seasonal allergy sufferers. Traditionally used in Chinese medicine as a preventive immune tonic for over 2,000 years.
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C
结论
A clinical trial found astragalus at 160 mg twice daily may help reduce sneezing and runny nose symptoms in seasonal allergy sufferers. Traditionally used in Chinese medicine as a preventive immune tonic for over 2,000 years.
Key Study Findings
Review
Rebalancing the inflammatory niche in allergic rhinitis ".
Dose: None
vs: None
Outcome: ILC2 suppression and mucosal homeostasis in allergic rhinitis
效果: None
None
研究人群: patients with allergic rhinitis (preclinical and some human data)
Review
Traditional Chinese Medicine for Allergic Rhinitis: Mechanisms, Evidence, and Gut-Immune Axis Targets.
Dose: None
vs: None
Outcome: TCM effects on allergic rhinitis via gut microbiota …
效果: None
None
研究人群: patients with allergic rhinitis (human and animal models)
Other
Network pharmacology analysis of the Huangqi-Gancao herb pair reveals quercetin as a therapeutics for allergic …
Dose: None
vs: OVA-induced AR mice without treatment
Outcome: Allergic rhinitis symptoms and histopathology
效果: None
None
研究人群: OVA-induced allergic rhinitis mouse model
In Vitro
Identification of Active Markers of Chinese Formula Yupingfeng San by Network Pharmacology and HPLC-Q-TOF-MS/MS Analysis …
Dose: None
vs: Allergic rhinitis mouse model vs control
Outcome: Nasal mucosal inflammation and serum markers
效果: None
None
研究人群: Allergic rhinitis mouse model
Other
A research method of compatibility mechanism of traditional Chinese medicine prescription-taking Yupingfeng San as an …
Dose: None
vs: Reduced component groups
Outcome: IL-2, IL-4, IGE, TGF-beta levels
效果: None
None
研究人群: Allergic rhinitis mouse model
Other
Astragalus polysaccharide alleviates IL-13-induced oxidative stress injury in nasal epithelial cells by inhibiting WTAP-mediated FBXW7 …
Dose: None
vs: None
Outcome: Oxidative stress markers
效果: None
None
研究人群: None
Key Statistics
3
研究数量
200
受试者
↑
Positive
C
等级
Referenced Papers
Clinica chimica acta; …
2026
Journal of asthma …
2026
Naunyn-Schmiedeberg's archives of …
2025
3 次引用
Pharmaceuticals (Basel, Switzerland)
2025
3 次引用
Journal of ethnopharmacology
2025
Corrigendum to Effect of Astragalus membranaceus in Ovalbumin-Induced Allergic Rhinitis Mouse Model.
Other
American journal of …
2025
Toxicology research
2024
5 次引用
American journal of …
2022
25 次引用
Computational and mathematical …
2022
8 次引用
Journal of medicinal …
2021
32 次引用
Bioengineered
2021
9 次引用
Frontiers in pharmacology
2020
21 次引用
American journal of …
2019
10 次引用
Journal of pharmaceutical …
2017
36 次引用
Molecular medicine reports
2017
21 次引用
[Effect of Astragalus membranaceus on Peripheral Blood Th17 in Patients with Allergic Rhinitis].
Other
Zhongguo Zhong xi …
2016
Journal of ethnopharmacology
2014
12 次引用
A stable fixed-dose combination tablet of pseudoephedrine and KOB extracts for the extended release.
Other
Drug research
2013
4 次引用
Zhong xi yi …
2011
Phytotherapy research : …
2010
61 次引用
Zhong xi yi …
2010
2 次引用
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
常用剂量
- general:
- 250-500 mg standardized extract/day
- traditional:
- 9-30 g dried root decoction/day
上限： No established UL
研究中使用的剂量
| 剂量 | 持续时间 | 效果 | N |
|---|---|---|---|
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
最佳服用时间： With meals; traditionally used as a preventive tonic (not during acute illness)
Safety & Side Effects
已报告的副作用
- ⚠ Generally well tolerated
- ⚠ Mild gastrointestinal effects (bloating, diarrhea) at high doses
- ⚠ Possible interaction with autoimmune conditions (immunostimulatory)
已知相互作用
- ● Immunosuppressant medications (may counteract immunosuppression)
- ● Lithium (may reduce lithium excretion)
- ● Cyclophosphamide (may enhance or interfere with effects)
可耐受最高摄入量： No established UL
在开始服用任何补充剂之前，请务必咨询您的医疗保健提供者。
Frequently Asked Questions
Does Astragalus help with 过敏性鼻炎?
Based on 3 studies with 200 participants, there is limited but promising evidence that Astragalus may support 过敏性鼻炎 management. Our evidence grade is C (Some Evidence).
How much Astragalus should I take for 过敏性鼻炎?
Studies have used various dosages. A commonly studied range is 250-500 mg standardized extract/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Astragalus?
Reported side effects may include Generally well tolerated, Mild gastrointestinal effects (bloating, diarrhea) at high doses, Possible interaction with autoimmune conditions (immunostimulatory). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Astragalus and 过敏性鼻炎?
We rate the evidence as Grade C (Some Evidence). This rating is based on 3 peer-reviewed studies with 200 total participants. The overall direction of effect is positive.
Related Evidence
其他成分用于 过敏性鼻炎
References
- [1] Ning Wang et al.. Clin Chim Acta. 2026. Rebalancing the inflammatory niche in allergic rhinitis ". doi:10.1016/j.cca.2025.120776 PubMed
- [2] Shuang Liu et al.. J Asthma Allergy. 2026. Traditional Chinese Medicine for Allergic Rhinitis: Mechanisms, Evidence, and Gut-Immune Axis Targets. doi:10.2147/JAA.S571460 PubMed
- [3] Yongjun Deng et al.. Naunyn Schmiedebergs Arch Pharmacol. 2025. Network pharmacology analysis of the Huangqi-Gancao herb pair reveals quercetin as a therapeutics for allergic rhinitis via the RELA-regulated IFNG/IRF1 … doi:10.1007/s00210-024-03353-8 PubMed
- [4] Xinqi Li et al.. Pharmaceuticals (Basel). 2025. Identification of Active Markers of Chinese Formula Yupingfeng San by Network Pharmacology and HPLC-Q-TOF-MS/MS Analysis in Experimental Allergic Rhinitis Models … doi:10.3390/ph18040540 PubMed
- [5] Xinyue Li et al.. J Ethnopharmacol. 2025. A research method of compatibility mechanism of traditional Chinese medicine prescription-taking Yupingfeng San as an example. doi:10.1016/j.jep.2025.119815 PubMed
- [6] . Am J Rhinol Allergy. 2025. Corrigendum to Effect of Astragalus membranaceus in Ovalbumin-Induced Allergic Rhinitis Mouse Model. doi:10.1177/1945892420979106 PubMed
- [7] Wei Cui et al.. Toxicol Res (Camb). 2024. Astragalus polysaccharide alleviates IL-13-induced oxidative stress injury in nasal epithelial cells by inhibiting WTAP-mediated FBXW7 m6A modification. doi:10.1093/toxres/tfae099 PubMed
- [8] Xian He et al.. Am J Rhinol Allergy. 2022. Astragalus Polysaccharide Relieves Inflammatory Responses in Guinea Pigs with Allergic Rhinitis via Ameliorating NF-kB-Mediated Treg/Th17 Imbalance. doi:10.1177/19458924221098847 PubMed
- [9] Min Shen et al.. Comput Math Methods Med. 2022. Effect of Traditional Chinese Medicine on Allergic Rhinitis in Children under Data Mining. doi:10.1155/2022/7007370 PubMed
- [10] Jiangtao Xu et al.. J Med Food. 2021. Astragalus Polysaccharides Attenuate Ovalbumin-Induced Allergic Rhinitis in Rats by Inhibiting NLRP3 Inflammasome Activation and NOD2-Mediated NF-κB Activation. doi:10.1089/jmf.2020.4750 PubMed
- [11] Jie Guo et al.. Bioengineered. 2021. Astragaloside IV suppresses histamine-induced inflammatory factors and mucin 5 subtype AC overproduction in nasal epithelial cells via regulation of inflammation-related … doi:10.1080/21655979.2021.1965813 PubMed
- [12] Saisai Wang et al.. Front Pharmacol. 2020. Astragalus Polysaccharides/Chitosan Microspheres for Nasal Delivery: Preparation, Optimization, Characterization, and Pharmacodynamics. doi:10.3389/fphar.2020.00230 PubMed
- [13] Zhong Bing et al.. Am J Rhinol Allergy. 2019. Effect of Astragalus membranaceus in Ovalbumin-Induced Allergic Rhinitis Mouse Model. doi:10.1177/1945892419839259 PubMed
- [14] Stefanie Nikles et al.. J Pharm Biomed Anal. 2017. Metabolic profiling of the traditional Chinese medicine formulation Yu Ping Feng San for the identification of constituents relevant for effects … doi:10.1016/j.jpba.2017.03.049 PubMed
- [15] Keqiong Li et al.. Mol Med Rep. 2017. Protective effects of astragaloside IV against ovalbumin-induced allergic rhinitis are mediated by T-box protein expressed in T cells/GATA-3 and forkhead … doi:10.3892/mmr.2017.6685 PubMed
- [16] Cheng Zhang et al.. Zhongguo Zhong Xi Yi Jie He Za Zhi. 2016. [Effect of Astragalus membranaceus on Peripheral Blood Th17 in Patients with Allergic Rhinitis]. PubMed
- [17] Kuilong Zhou et al.. J Ethnopharmacol. 2014. Qu Feng Xuan Bi Formula attenuates anaphylactic rhinitis-asthma symptoms via reducing EOS count and regulating T cell function in rat … doi:10.1016/j.jep.2014.02.006 PubMed
- [18] C-J Hwang et al.. Drug Res (Stuttg). 2013. A stable fixed-dose combination tablet of pseudoephedrine and KOB extracts for the extended release. doi:10.1055/s-0033-1348222 PubMed
- [19] Jian Cheng et al.. Zhong Xi Yi Jie He Xue Bao. 2011. [Immunoregulatory mechanisms of an optimal Chinese herbal monomer compound in mice with allergic rhinitis]. doi:10.3736/jcim20111213 PubMed
- [20] Zinka Matkovic et al.. Phytother Res. 2010. Efficacy and safety of Astragalus membranaceus in the treatment of patients with seasonal allergic rhinitis. doi:10.1002/ptr.2877 PubMed
- [21] Wei-Yi Gong et al.. Zhong Xi Yi Jie He Xue Bao. 2010. [Optimal combination of baicalin, icariin and Astragalus saponin I from a Chinese herbal compound Biminne]. doi:10.3736/jcim20100606 PubMed
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