Spirulina 用于 过敏性鼻炎
C 证据 来自小型研究的证据有限，但存在一些积极信号。A 2020 comparative trial found spirulina was more effective than cetirizine (a standard antihistamine) in improving allergic rhinitis symptoms. Earlier studies show enhancement of NK cell function in a majority of subjects.
<\/script>\n`;
},
get iframeSnippet() {
const domain = 'immunecited.com';
const params = 'ingredient\u003Dspirulina\u0026condition\u003Dallergic\u002Drhinitis';
return ``;
},
get activeSnippet() {
return this.method === 'script' ? this.scriptSnippet : this.iframeSnippet;
},
copySnippet() {
navigator.clipboard.writeText(this.activeSnippet).then(() => {
this.copied = true;
setTimeout(() => { this.copied = false; }, 2000);
});
}
}"
@keydown.escape.window="open = false"
@click.outside="open = false">
C
结论
A 2020 comparative trial found spirulina was more effective than cetirizine (a standard antihistamine) in improving allergic rhinitis symptoms. Earlier studies show enhancement of NK cell function in a majority of subjects.
Key Study Findings
Controlled Clinical Trial
6 weeks
Supplementation With Spirulina platensis Improves Tracheal Reactivity in Wistar Rats by Modulating Inflammation and Oxidative …
Dose: 50 mg/kg/day
vs: OVA-sensitized control without Spirulina
Outcome: Tracheal reactivity to acetylcholine and citric acid
效果: None
None
研究人群: OVA-sensitized Wistar rats
Other
12 weeks
Can selenium-enriched spirulina supplementation ameliorate sepsis outcomes in selenium-deficient animals?
Dose: 92%
vs: None
Outcome: by ICPMS
效果: or 4
None
研究人群: None
Randomized Controlled Trial
n=76
Open-label
Effect of nasal irrigation on allergic rhinitis control in children; complementarity between CARAT and MASK …
Dose: None
vs: Control group
Outcome: symptom control, assessed by the control of allergic …
效果: None
p = 0.035
研究人群: Allergic rhinitis patients
In Vitro
Immunomodulatory and Inhibitory Effect of Immulina®, and Immunloges® in the Ig-E Mediated Activation of RBL-2H3 …
Dose: None
vs: None
Outcome: IgE-mediated TNF-alpha and histamine release
效果: None
None
研究人群: RBL-2H3 mast cells
Review
Benefits, pitfalls and risks of phytotherapy in clinical practice in otorhinolaryngology.
Dose: None
vs: None
Outcome: None
效果: None
None
研究人群: Otorhinolaryngology patients (phytotherapy)
Review
Recent Patents of Complementary and Alternative Medicine for Allergic Rhinitis.
Dose: None
vs: None
Outcome: None
效果: None
None
研究人群: allergic rhinitis patients
Key Statistics
3
研究数量
150
受试者
↑
Positive
C
等级
Referenced Papers
Frontiers in pharmacology
2022
5 次引用
Physiological reports
2021
3 次引用
Clinical and translational …
2020
20 次引用
Acta otorhinolaryngologica Italica …
2020
11 次引用
Plants (Basel, Switzerland)
2018
23 次引用
European annals of …
2017
16 次引用
Recent patents on …
2015
16 次引用
ISRN allergy
2013
19 次引用
Current opinion in …
2009
26 次引用
European archives of …
2008
91 次引用
'Complementary ENT': a systematic review of commonly used supplements.
Systematic Review
The Journal of …
2007
39 次引用
Journal of medicinal …
2005
195 次引用
Zhong nan da …
2005
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
常用剂量
- general:
- 1-3 g/day
- immunesupport:
- 3-10 g/day
上限： No established UL; 10 g/day widely studied
研究中使用的剂量
| 剂量 | 持续时间 | 效果 | N |
|---|---|---|---|
| 50 mg/kg/day | 6 weeks | Positive | -- |
| 92% | 12 weeks | Positive | -- |
| None | -- | Positive | 76 |
| None | -- | Positive | -- |
| None | -- | Mixed | -- |
| None | -- | Positive | -- |
| None | -- | Neutral | 230 |
| None | -- | Positive | -- |
最佳服用时间： With or without food
Safety & Side Effects
已报告的副作用
- ⚠ Gastrointestinal discomfort
- ⚠ Headache
- ⚠ Allergic reactions (rare)
- ⚠ Contamination risk from wild-harvested sources (microcystins, heavy metals)
- ⚠ May exacerbate autoimmune conditions (immunostimulatory)
已知相互作用
- ● Immunosuppressant medications (may counteract immunosuppression)
- ● Anticoagulants (may have additive effects)
- ● Diabetes medications (may lower blood sugar)
可耐受最高摄入量： No established UL; 10 g/day widely studied
在开始服用任何补充剂之前，请务必咨询您的医疗保健提供者。
Frequently Asked Questions
Does Spirulina help with 过敏性鼻炎?
Based on 3 studies with 150 participants, there is limited but promising evidence that Spirulina may support 过敏性鼻炎 management. Our evidence grade is C (Some Evidence).
How much Spirulina should I take for 过敏性鼻炎?
Studies have used various dosages. A commonly studied range is 1-3 g/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Spirulina?
Reported side effects may include Gastrointestinal discomfort, Headache, Allergic reactions (rare), Contamination risk from wild-harvested sources (microcystins, heavy metals). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Spirulina and 过敏性鼻炎?
We rate the evidence as Grade C (Some Evidence). This rating is based on 3 peer-reviewed studies with 150 total participants. The overall direction of effect is positive.
Related Evidence
其他成分用于 过敏性鼻炎
References
- [1] Aline de F Brito et al.. Front Pharmacol. 2022. Supplementation With Spirulina platensis Improves Tracheal Reactivity in Wistar Rats by Modulating Inflammation and Oxidative Stress. doi:10.3389/fphar.2022.826649 PubMed
- [2] Thomas Castel et al.. Physiol Rep. 2021. Can selenium-enriched spirulina supplementation ameliorate sepsis outcomes in selenium-deficient animals? doi:10.14814/phy2.14933 PubMed
- [3] Dimitrios I Mitsias et al.. Clin Transl Allergy. 2020. Effect of nasal irrigation on allergic rhinitis control in children; complementarity between CARAT and MASK outcomes. doi:10.1186/s13601-020-00313-2 PubMed
- [4] Morteza Nourollahian et al.. Acta Otorhinolaryngol Ital. 2020. Clinical comparison of the efficacy of spirulina platensis and cetirizine for treatment of allergic rhinitis. doi:10.14639/0392-100X-N0139 PubMed
- [5] Kurt Appel et al.. Plants (Basel). 2018. Immunomodulatory and Inhibitory Effect of Immulina®, and Immunloges® in the Ig-E Mediated Activation of RBL-2H3 Cells. A New Role in … doi:10.3390/plants7010013 PubMed
- [6] O Laccourreye et al.. Eur Ann Otorhinolaryngol Head Neck Dis. 2017. Benefits, pitfalls and risks of phytotherapy in clinical practice in otorhinolaryngology. doi:10.1016/j.anorl.2016.11.001 PubMed
- [7] Kam L Hon et al.. Recent Pat Inflamm Allergy Drug Discov. 2015. Recent Patents of Complementary and Alternative Medicine for Allergic Rhinitis. doi:10.2174/1872213x10666151119144718 PubMed
- [8] Ibrahim Sayin et al.. ISRN Allergy. 2013. Complementary therapies in allergic rhinitis. doi:10.1155/2013/938751 PubMed
- [9] Li-Xing Man. Curr Opin Otolaryngol Head Neck Surg. 2009. Complementary and alternative medicine for allergic rhinitis. doi:10.1097/MOO.0b013e3283295791 PubMed
- [10] Cemal Cingi et al.. Eur Arch Otorhinolaryngol. 2008. The effects of spirulina on allergic rhinitis. doi:10.1007/s00405-008-0642-8 PubMed
- [11] P D Karkos et al.. J Laryngol Otol. 2007. 'Complementary ENT': a systematic review of commonly used supplements. doi:10.1017/S002221510600449X PubMed
- [12] T K Mao et al.. J Med Food. 2005. Effects of a Spirulina-based dietary supplement on cytokine production from allergic rhinitis patients. doi:10.1089/jmf.2005.8.27 PubMed
- [13] Li-lan Chen et al.. Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2005. [Experimental study of spirulina platensis in treating allergic rhinitis in rats]. PubMed
FDA 免责声明: 这些声明未经美国食品药品监督管理局（FDA）评估。本网站上的产品和信息无意用于诊断、治疗、治愈或预防任何疾病。所展示的证据等级基于我们对已发表的同行评审研究的分析，不构成医疗建议。在开始任何补充剂方案之前，请务必咨询您的医疗保健提供者。