Spirulina para Allergic Rhinitis

C Evidências Evidência limitada de estudos de pequena dimensão, mas existem alguns sinais positivos.

A 2020 comparative trial found spirulina was more effective than cetirizine (a standard antihistamine) in improving allergic rhinitis symptoms. Earlier studies show enhancement of NK cell function in a majority of subjects.

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Conclusão

Key Study Findings

Controlled Clinical Trial 6 weeks

Supplementation With Spirulina platensis Improves Tracheal Reactivity in Wistar Rats by Modulating Inflammation and Oxidative …

Dose: 50 mg/kg/day vs: OVA-sensitized control without Spirulina Outcome: Tracheal reactivity to acetylcholine and citric acid Efeito: None None

População: OVA-sensitized Wistar rats

Other 12 weeks

Can selenium-enriched spirulina supplementation ameliorate sepsis outcomes in selenium-deficient animals?

Dose: 92% vs: None Outcome: by ICPMS Efeito: or 4 None

População: None

Randomized Controlled Trial n=76 Open-label

Effect of nasal irrigation on allergic rhinitis control in children; complementarity between CARAT and MASK …

Dose: None vs: Control group Outcome: symptom control, assessed by the control of allergic … Efeito: None p = 0.035

População: Allergic rhinitis patients

In Vitro

Immunomodulatory and Inhibitory Effect of Immulina®, and Immunloges® in the Ig-E Mediated Activation of RBL-2H3 …

Dose: None vs: None Outcome: IgE-mediated TNF-alpha and histamine release Efeito: None None

População: RBL-2H3 mast cells

Review

Benefits, pitfalls and risks of phytotherapy in clinical practice in otorhinolaryngology.

Dose: None vs: None Outcome: None Efeito: None None

População: Otorhinolaryngology patients (phytotherapy)

Review

Recent Patents of Complementary and Alternative Medicine for Allergic Rhinitis.

Dose: None vs: None Outcome: None Efeito: None None

População: allergic rhinitis patients

Key Statistics

Estudos

150

Participantes

↑

Positive

Nota

Referenced Papers

Supplementation With Spirulina platensis Improves Tracheal Reactivity in Wistar Rats by Modulating Inflammation and Oxidative Stress. Other

Frontiers in pharmacology 2022 5 citações

Can selenium-enriched spirulina supplementation ameliorate sepsis outcomes in selenium-deficient animals? Other

Physiological reports 2021 3 citações

Effect of nasal irrigation on allergic rhinitis control in children; complementarity between CARAT and MASK outcomes. Other

Clinical and translational … 2020 20 citações

Clinical comparison of the efficacy of spirulina platensis and cetirizine for treatment of allergic rhinitis. RCT

Acta otorhinolaryngologica Italica … 2020 11 citações

Immunomodulatory and Inhibitory Effect of Immulina®, and Immunloges® in the Ig-E Mediated Activation of RBL-2H3 Cells. A New Role in … Other

Plants (Basel, Switzerland) 2018 23 citações

Benefits, pitfalls and risks of phytotherapy in clinical practice in otorhinolaryngology. Review

European annals of … 2017 16 citações

Recent Patents of Complementary and Alternative Medicine for Allergic Rhinitis. Review

Recent patents on … 2015 16 citações

Complementary therapies in allergic rhinitis. Other

ISRN allergy 2013 19 citações

Complementary and alternative medicine for allergic rhinitis. Review

Current opinion in … 2009 26 citações

The effects of spirulina on allergic rhinitis. RCT

European archives of … 2008 91 citações

'Complementary ENT': a systematic review of commonly used supplements. Systematic Review

The Journal of … 2007 39 citações

Effects of a Spirulina-based dietary supplement on cytokine production from allergic rhinitis patients. RCT

Journal of medicinal … 2005 195 citações

[Experimental study of spirulina platensis in treating allergic rhinitis in rats]. Other

Zhong nan da … 2005

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Dosagens Comumente Utilizadas

general:: 1-3 g/day
immunesupport:: 3-10 g/day

Limite superior: No established UL; 10 g/day widely studied

Dosagens Estudadas em Pesquisas

Dosagem	Duração	Efeito	N
50 mg/kg/day	6 weeks	Positive	--
92%	12 weeks	Positive	--
None	--	Positive	76
None	--	Positive	--
None	--	Mixed	--
None	--	Positive	--
None	--	Neutral	230
None	--	Positive	--

Melhor horário: With or without food

Safety & Side Effects

Efeitos Colaterais Relatados

⚠ Gastrointestinal discomfort
⚠ Headache
⚠ Allergic reactions (rare)
⚠ Contamination risk from wild-harvested sources (microcystins, heavy metals)
⚠ May exacerbate autoimmune conditions (immunostimulatory)

Interações Conhecidas

● Immunosuppressant medications (may counteract immunosuppression)
● Anticoagulants (may have additive effects)
● Diabetes medications (may lower blood sugar)

Ingestão máxima tolerável: No established UL; 10 g/day widely studied

Consulte sempre o seu profissional de saúde antes de iniciar qualquer suplemento.Sempre consulte seu profissional de saúde antes de iniciar qualquer suplemento.

Frequently Asked Questions

Does Spirulina help with Allergic Rhinitis?

Based on 3 studies with 150 participants, there is limited but promising evidence that Spirulina may support Allergic Rhinitis management. Our evidence grade is C (Some Evidence).

How much Spirulina should I take for Allergic Rhinitis?

Studies have used various dosages. A commonly studied range is 1-3 g/day. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Spirulina?

Reported side effects may include Gastrointestinal discomfort, Headache, Allergic reactions (rare), Contamination risk from wild-harvested sources (microcystins, heavy metals). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Spirulina and Allergic Rhinitis?

We rate the evidence as Grade C (Some Evidence). This rating is based on 3 peer-reviewed studies with 150 total participants. The overall direction of effect is positive.

Outros ingredientes para Allergic Rhinitis

Quercetin C Astragalus C

Veredito Rápido

Evidence Strength52%

Moderate confidence

Detalhamento dos Estudos

RCT (3)Meta (0)Other (0)

Comparar Alternativas

Veja como outros ingredientes se comparam para esta condição.

Ver todos os ingredientes para Allergic Rhinitis

Saiba Mais

References

[1] Aline de F Brito et al.. Front Pharmacol. 2022. Supplementation With Spirulina platensis Improves Tracheal Reactivity in Wistar Rats by Modulating Inflammation and Oxidative Stress. doi:10.3389/fphar.2022.826649 PubMed
[2] Thomas Castel et al.. Physiol Rep. 2021. Can selenium-enriched spirulina supplementation ameliorate sepsis outcomes in selenium-deficient animals? doi:10.14814/phy2.14933 PubMed
[3] Dimitrios I Mitsias et al.. Clin Transl Allergy. 2020. Effect of nasal irrigation on allergic rhinitis control in children; complementarity between CARAT and MASK outcomes. doi:10.1186/s13601-020-00313-2 PubMed
[4] Morteza Nourollahian et al.. Acta Otorhinolaryngol Ital. 2020. Clinical comparison of the efficacy of spirulina platensis and cetirizine for treatment of allergic rhinitis. doi:10.14639/0392-100X-N0139 PubMed
[5] Kurt Appel et al.. Plants (Basel). 2018. Immunomodulatory and Inhibitory Effect of Immulina®, and Immunloges® in the Ig-E Mediated Activation of RBL-2H3 Cells. A New Role in … doi:10.3390/plants7010013 PubMed
[6] O Laccourreye et al.. Eur Ann Otorhinolaryngol Head Neck Dis. 2017. Benefits, pitfalls and risks of phytotherapy in clinical practice in otorhinolaryngology. doi:10.1016/j.anorl.2016.11.001 PubMed
[7] Kam L Hon et al.. Recent Pat Inflamm Allergy Drug Discov. 2015. Recent Patents of Complementary and Alternative Medicine for Allergic Rhinitis. doi:10.2174/1872213x10666151119144718 PubMed
[8] Ibrahim Sayin et al.. ISRN Allergy. 2013. Complementary therapies in allergic rhinitis. doi:10.1155/2013/938751 PubMed
[9] Li-Xing Man. Curr Opin Otolaryngol Head Neck Surg. 2009. Complementary and alternative medicine for allergic rhinitis. doi:10.1097/MOO.0b013e3283295791 PubMed
[10] Cemal Cingi et al.. Eur Arch Otorhinolaryngol. 2008. The effects of spirulina on allergic rhinitis. doi:10.1007/s00405-008-0642-8 PubMed
[11] P D Karkos et al.. J Laryngol Otol. 2007. 'Complementary ENT': a systematic review of commonly used supplements. doi:10.1017/S002221510600449X PubMed
[12] T K Mao et al.. J Med Food. 2005. Effects of a Spirulina-based dietary supplement on cytokine production from allergic rhinitis patients. doi:10.1089/jmf.2005.8.27 PubMed
[13] Li-lan Chen et al.. Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2005. [Experimental study of spirulina platensis in treating allergic rhinitis in rats]. PubMed

Aviso Legal da FDA: Estas declarações não foram avaliadas pela Food and Drug Administration. Os produtos e informações neste site não se destinam a diagnosticar, tratar, curar ou prevenir qualquer doença. As notas de evidência apresentadas são baseadas em nossa análise de pesquisas revisadas por pares publicadas e não constituem aconselhamento médico. Sempre consulte seu profissional de saúde antes de iniciar qualquer regime de suplementação.