Spirulina 관련 알레르기성 비염
C 근거 소규모 연구에서의 근거는 제한적이지만, 일부 긍정적인 신호가 존재합니다.A 2020 comparative trial found spirulina was more effective than cetirizine (a standard antihistamine) in improving allergic rhinitis symptoms. Earlier studies show enhancement of NK cell function in a majority of subjects.
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C
결론
A 2020 comparative trial found spirulina was more effective than cetirizine (a standard antihistamine) in improving allergic rhinitis symptoms. Earlier studies show enhancement of NK cell function in a majority of subjects.
Key Study Findings
Controlled Clinical Trial
6 weeks
Supplementation With Spirulina platensis Improves Tracheal Reactivity in Wistar Rats by Modulating Inflammation and Oxidative …
Dose: 50 mg/kg/day
vs: OVA-sensitized control without Spirulina
Outcome: Tracheal reactivity to acetylcholine and citric acid
효과: None
None
대상 집단: OVA-sensitized Wistar rats
Other
12 weeks
Can selenium-enriched spirulina supplementation ameliorate sepsis outcomes in selenium-deficient animals?
Dose: 92%
vs: None
Outcome: by ICPMS
효과: or 4
None
대상 집단: None
Randomized Controlled Trial
n=76
Open-label
Effect of nasal irrigation on allergic rhinitis control in children; complementarity between CARAT and MASK …
Dose: None
vs: Control group
Outcome: symptom control, assessed by the control of allergic …
효과: None
p = 0.035
대상 집단: Allergic rhinitis patients
In Vitro
Immunomodulatory and Inhibitory Effect of Immulina®, and Immunloges® in the Ig-E Mediated Activation of RBL-2H3 …
Dose: None
vs: None
Outcome: IgE-mediated TNF-alpha and histamine release
효과: None
None
대상 집단: RBL-2H3 mast cells
Review
Benefits, pitfalls and risks of phytotherapy in clinical practice in otorhinolaryngology.
Dose: None
vs: None
Outcome: None
효과: None
None
대상 집단: Otorhinolaryngology patients (phytotherapy)
Review
Recent Patents of Complementary and Alternative Medicine for Allergic Rhinitis.
Dose: None
vs: None
Outcome: None
효과: None
None
대상 집단: allergic rhinitis patients
Key Statistics
3
연구
150
참여자
↑
Positive
C
등급
Referenced Papers
Frontiers in pharmacology
2022
5 인용
Physiological reports
2021
3 인용
Clinical and translational …
2020
20 인용
Acta otorhinolaryngologica Italica …
2020
11 인용
Plants (Basel, Switzerland)
2018
23 인용
European annals of …
2017
16 인용
Recent patents on …
2015
16 인용
ISRN allergy
2013
19 인용
Current opinion in …
2009
26 인용
European archives of …
2008
91 인용
'Complementary ENT': a systematic review of commonly used supplements.
Systematic Review
The Journal of …
2007
39 인용
Journal of medicinal …
2005
195 인용
Zhong nan da …
2005
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
일반적으로 사용되는 용량
- general:
- 1-3 g/day
- immunesupport:
- 3-10 g/day
상한량: No established UL; 10 g/day widely studied
연구에서 사용된 용량
| 용량 | 기간 | 효과 | N |
|---|---|---|---|
| 50 mg/kg/day | 6 weeks | Positive | -- |
| 92% | 12 weeks | Positive | -- |
| None | -- | Positive | 76 |
| None | -- | Positive | -- |
| None | -- | Mixed | -- |
| None | -- | Positive | -- |
| None | -- | Neutral | 230 |
| None | -- | Positive | -- |
권장 복용 시간: With or without food
Safety & Side Effects
보고된 부작용
- ⚠ Gastrointestinal discomfort
- ⚠ Headache
- ⚠ Allergic reactions (rare)
- ⚠ Contamination risk from wild-harvested sources (microcystins, heavy metals)
- ⚠ May exacerbate autoimmune conditions (immunostimulatory)
알려진 상호작용
- ● Immunosuppressant medications (may counteract immunosuppression)
- ● Anticoagulants (may have additive effects)
- ● Diabetes medications (may lower blood sugar)
일일 최대 섭취 허용량: No established UL; 10 g/day widely studied
건강기능식품을 복용하기 전에 반드시 의료 전문가와 상담하십시오.
Frequently Asked Questions
Does Spirulina help with 알레르기성 비염?
Based on 3 studies with 150 participants, there is limited but promising evidence that Spirulina may support 알레르기성 비염 management. Our evidence grade is C (Some Evidence).
How much Spirulina should I take for 알레르기성 비염?
Studies have used various dosages. A commonly studied range is 1-3 g/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Spirulina?
Reported side effects may include Gastrointestinal discomfort, Headache, Allergic reactions (rare), Contamination risk from wild-harvested sources (microcystins, heavy metals). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Spirulina and 알레르기성 비염?
We rate the evidence as Grade C (Some Evidence). This rating is based on 3 peer-reviewed studies with 150 total participants. The overall direction of effect is positive.
Related Evidence
References
- [1] Aline de F Brito et al.. Front Pharmacol. 2022. Supplementation With Spirulina platensis Improves Tracheal Reactivity in Wistar Rats by Modulating Inflammation and Oxidative Stress. doi:10.3389/fphar.2022.826649 PubMed
- [2] Thomas Castel et al.. Physiol Rep. 2021. Can selenium-enriched spirulina supplementation ameliorate sepsis outcomes in selenium-deficient animals? doi:10.14814/phy2.14933 PubMed
- [3] Dimitrios I Mitsias et al.. Clin Transl Allergy. 2020. Effect of nasal irrigation on allergic rhinitis control in children; complementarity between CARAT and MASK outcomes. doi:10.1186/s13601-020-00313-2 PubMed
- [4] Morteza Nourollahian et al.. Acta Otorhinolaryngol Ital. 2020. Clinical comparison of the efficacy of spirulina platensis and cetirizine for treatment of allergic rhinitis. doi:10.14639/0392-100X-N0139 PubMed
- [5] Kurt Appel et al.. Plants (Basel). 2018. Immunomodulatory and Inhibitory Effect of Immulina®, and Immunloges® in the Ig-E Mediated Activation of RBL-2H3 Cells. A New Role in … doi:10.3390/plants7010013 PubMed
- [6] O Laccourreye et al.. Eur Ann Otorhinolaryngol Head Neck Dis. 2017. Benefits, pitfalls and risks of phytotherapy in clinical practice in otorhinolaryngology. doi:10.1016/j.anorl.2016.11.001 PubMed
- [7] Kam L Hon et al.. Recent Pat Inflamm Allergy Drug Discov. 2015. Recent Patents of Complementary and Alternative Medicine for Allergic Rhinitis. doi:10.2174/1872213x10666151119144718 PubMed
- [8] Ibrahim Sayin et al.. ISRN Allergy. 2013. Complementary therapies in allergic rhinitis. doi:10.1155/2013/938751 PubMed
- [9] Li-Xing Man. Curr Opin Otolaryngol Head Neck Surg. 2009. Complementary and alternative medicine for allergic rhinitis. doi:10.1097/MOO.0b013e3283295791 PubMed
- [10] Cemal Cingi et al.. Eur Arch Otorhinolaryngol. 2008. The effects of spirulina on allergic rhinitis. doi:10.1007/s00405-008-0642-8 PubMed
- [11] P D Karkos et al.. J Laryngol Otol. 2007. 'Complementary ENT': a systematic review of commonly used supplements. doi:10.1017/S002221510600449X PubMed
- [12] T K Mao et al.. J Med Food. 2005. Effects of a Spirulina-based dietary supplement on cytokine production from allergic rhinitis patients. doi:10.1089/jmf.2005.8.27 PubMed
- [13] Li-lan Chen et al.. Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2005. [Experimental study of spirulina platensis in treating allergic rhinitis in rats]. PubMed
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