Spirulina per Allergic Rhinitis

C Evidenze Evidenza limitata da studi di piccole dimensioni, ma esistono alcuni segnali positivi.

A 2020 comparative trial found spirulina was more effective than cetirizine (a standard antihistamine) in improving allergic rhinitis symptoms. Earlier studies show enhancement of NK cell function in a majority of subjects.

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In sintesi

Key Study Findings

Controlled Clinical Trial 6 weeks

Supplementation With Spirulina platensis Improves Tracheal Reactivity in Wistar Rats by Modulating Inflammation and Oxidative …

Dose: 50 mg/kg/day vs: OVA-sensitized control without Spirulina Outcome: Tracheal reactivity to acetylcholine and citric acid Effetto: None None

Popolazione: OVA-sensitized Wistar rats

Other 12 weeks

Can selenium-enriched spirulina supplementation ameliorate sepsis outcomes in selenium-deficient animals?

Dose: 92% vs: None Outcome: by ICPMS Effetto: or 4 None

Popolazione: None

Randomized Controlled Trial n=76 Open-label

Effect of nasal irrigation on allergic rhinitis control in children; complementarity between CARAT and MASK …

Dose: None vs: Control group Outcome: symptom control, assessed by the control of allergic … Effetto: None p = 0.035

Popolazione: Allergic rhinitis patients

In Vitro

Immunomodulatory and Inhibitory Effect of Immulina®, and Immunloges® in the Ig-E Mediated Activation of RBL-2H3 …

Dose: None vs: None Outcome: IgE-mediated TNF-alpha and histamine release Effetto: None None

Popolazione: RBL-2H3 mast cells

Review

Benefits, pitfalls and risks of phytotherapy in clinical practice in otorhinolaryngology.

Dose: None vs: None Outcome: None Effetto: None None

Popolazione: Otorhinolaryngology patients (phytotherapy)

Review

Recent Patents of Complementary and Alternative Medicine for Allergic Rhinitis.

Dose: None vs: None Outcome: None Effetto: None None

Popolazione: allergic rhinitis patients

Key Statistics

Studi

150

Partecipanti

↑

Positive

Grado

Referenced Papers

Supplementation With Spirulina platensis Improves Tracheal Reactivity in Wistar Rats by Modulating Inflammation and Oxidative Stress. Other

Frontiers in pharmacology 2022 5 citazioni

Can selenium-enriched spirulina supplementation ameliorate sepsis outcomes in selenium-deficient animals? Other

Physiological reports 2021 3 citazioni

Effect of nasal irrigation on allergic rhinitis control in children; complementarity between CARAT and MASK outcomes. Other

Clinical and translational … 2020 20 citazioni

Clinical comparison of the efficacy of spirulina platensis and cetirizine for treatment of allergic rhinitis. RCT

Acta otorhinolaryngologica Italica … 2020 11 citazioni

Immunomodulatory and Inhibitory Effect of Immulina®, and Immunloges® in the Ig-E Mediated Activation of RBL-2H3 Cells. A New Role in … Other

Plants (Basel, Switzerland) 2018 23 citazioni

Benefits, pitfalls and risks of phytotherapy in clinical practice in otorhinolaryngology. Review

European annals of … 2017 16 citazioni

Recent Patents of Complementary and Alternative Medicine for Allergic Rhinitis. Review

Recent patents on … 2015 16 citazioni

Complementary therapies in allergic rhinitis. Other

ISRN allergy 2013 19 citazioni

Complementary and alternative medicine for allergic rhinitis. Review

Current opinion in … 2009 26 citazioni

The effects of spirulina on allergic rhinitis. RCT

European archives of … 2008 91 citazioni

'Complementary ENT': a systematic review of commonly used supplements. Systematic Review

The Journal of … 2007 39 citazioni

Effects of a Spirulina-based dietary supplement on cytokine production from allergic rhinitis patients. RCT

Journal of medicinal … 2005 195 citazioni

[Experimental study of spirulina platensis in treating allergic rhinitis in rats]. Other

Zhong nan da … 2005

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Dosaggi di uso comune

general:: 1-3 g/day
immunesupport:: 3-10 g/day

Limite massimo: No established UL; 10 g/day widely studied

Dosaggi studiati nella ricerca

Dosaggio	Durata	Effetto	N
50 mg/kg/day	6 weeks	Positive	--
92%	12 weeks	Positive	--
None	--	Positive	76
None	--	Positive	--
None	--	Mixed	--
None	--	Positive	--
None	--	Neutral	230
None	--	Positive	--

Momento migliore per l'assunzione: With or without food

Safety & Side Effects

Effetti collaterali segnalati

⚠ Gastrointestinal discomfort
⚠ Headache
⚠ Allergic reactions (rare)
⚠ Contamination risk from wild-harvested sources (microcystins, heavy metals)
⚠ May exacerbate autoimmune conditions (immunostimulatory)

Interazioni note

● Immunosuppressant medications (may counteract immunosuppression)
● Anticoagulants (may have additive effects)
● Diabetes medications (may lower blood sugar)

Livello di assunzione massimo tollerabile: No established UL; 10 g/day widely studied

Consultare sempre il proprio medico prima di iniziare qualsiasi integratore.Consultate sempre il vostro medico prima di iniziare qualsiasi integratore.

Frequently Asked Questions

Does Spirulina help with Allergic Rhinitis?

Based on 3 studies with 150 participants, there is limited but promising evidence that Spirulina may support Allergic Rhinitis management. Our evidence grade is C (Some Evidence).

How much Spirulina should I take for Allergic Rhinitis?

Studies have used various dosages. A commonly studied range is 1-3 g/day. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Spirulina?

Reported side effects may include Gastrointestinal discomfort, Headache, Allergic reactions (rare), Contamination risk from wild-harvested sources (microcystins, heavy metals). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Spirulina and Allergic Rhinitis?

We rate the evidence as Grade C (Some Evidence). This rating is based on 3 peer-reviewed studies with 150 total participants. The overall direction of effect is positive.

Altri ingredienti per Allergic Rhinitis

Quercetin C Astragalus C

Verdetto rapido

Evidence Strength52%

Moderate confidence

Analisi degli studi

RCT (3)Meta (0)Other (0)

Confronta le alternative

Scoprite come si confrontano altri ingredienti per questa condizione.

Visualizza tutti gli ingredienti per Allergic Rhinitis

Approfondimenti

References

[1] Aline de F Brito et al.. Front Pharmacol. 2022. Supplementation With Spirulina platensis Improves Tracheal Reactivity in Wistar Rats by Modulating Inflammation and Oxidative Stress. doi:10.3389/fphar.2022.826649 PubMed
[2] Thomas Castel et al.. Physiol Rep. 2021. Can selenium-enriched spirulina supplementation ameliorate sepsis outcomes in selenium-deficient animals? doi:10.14814/phy2.14933 PubMed
[3] Dimitrios I Mitsias et al.. Clin Transl Allergy. 2020. Effect of nasal irrigation on allergic rhinitis control in children; complementarity between CARAT and MASK outcomes. doi:10.1186/s13601-020-00313-2 PubMed
[4] Morteza Nourollahian et al.. Acta Otorhinolaryngol Ital. 2020. Clinical comparison of the efficacy of spirulina platensis and cetirizine for treatment of allergic rhinitis. doi:10.14639/0392-100X-N0139 PubMed
[5] Kurt Appel et al.. Plants (Basel). 2018. Immunomodulatory and Inhibitory Effect of Immulina®, and Immunloges® in the Ig-E Mediated Activation of RBL-2H3 Cells. A New Role in … doi:10.3390/plants7010013 PubMed
[6] O Laccourreye et al.. Eur Ann Otorhinolaryngol Head Neck Dis. 2017. Benefits, pitfalls and risks of phytotherapy in clinical practice in otorhinolaryngology. doi:10.1016/j.anorl.2016.11.001 PubMed
[7] Kam L Hon et al.. Recent Pat Inflamm Allergy Drug Discov. 2015. Recent Patents of Complementary and Alternative Medicine for Allergic Rhinitis. doi:10.2174/1872213x10666151119144718 PubMed
[8] Ibrahim Sayin et al.. ISRN Allergy. 2013. Complementary therapies in allergic rhinitis. doi:10.1155/2013/938751 PubMed
[9] Li-Xing Man. Curr Opin Otolaryngol Head Neck Surg. 2009. Complementary and alternative medicine for allergic rhinitis. doi:10.1097/MOO.0b013e3283295791 PubMed
[10] Cemal Cingi et al.. Eur Arch Otorhinolaryngol. 2008. The effects of spirulina on allergic rhinitis. doi:10.1007/s00405-008-0642-8 PubMed
[11] P D Karkos et al.. J Laryngol Otol. 2007. 'Complementary ENT': a systematic review of commonly used supplements. doi:10.1017/S002221510600449X PubMed
[12] T K Mao et al.. J Med Food. 2005. Effects of a Spirulina-based dietary supplement on cytokine production from allergic rhinitis patients. doi:10.1089/jmf.2005.8.27 PubMed
[13] Li-lan Chen et al.. Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2005. [Experimental study of spirulina platensis in treating allergic rhinitis in rats]. PubMed

Avvertenza FDA: Queste affermazioni non sono state valutate dalla Food and Drug Administration. I prodotti e le informazioni presenti su questo sito web non sono destinati a diagnosticare, trattare, curare o prevenire alcuna malattia. I gradi di evidenza presentati si basano sulla nostra analisi della ricerca pubblicata e sottoposta a revisione paritaria e non costituiscono consulenza medica. Consultate sempre il vostro medico prima di iniziare qualsiasi regime di integrazione.