Astragalus für Allergic Rhinitis
C Evidenz Begrenzte Evidenz aus kleinen Studien, aber es gibt einige positive Signale.A clinical trial found astragalus at 160 mg twice daily may help reduce sneezing and runny nose symptoms in seasonal allergy sufferers. Traditionally used in Chinese medicine as a preventive immune tonic for over 2,000 years.
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C
Fazit
A clinical trial found astragalus at 160 mg twice daily may help reduce sneezing and runny nose symptoms in seasonal allergy sufferers. Traditionally used in Chinese medicine as a preventive immune tonic for over 2,000 years.
Key Study Findings
Review
Rebalancing the inflammatory niche in allergic rhinitis ".
Dose: None
vs.: None
Outcome: ILC2 suppression and mucosal homeostasis in allergic rhinitis
Wirkung: None
None
Population: patients with allergic rhinitis (preclinical and some human data)
Review
Traditional Chinese Medicine for Allergic Rhinitis: Mechanisms, Evidence, and Gut-Immune Axis Targets.
Dose: None
vs.: None
Outcome: TCM effects on allergic rhinitis via gut microbiota …
Wirkung: None
None
Population: patients with allergic rhinitis (human and animal models)
Other
Network pharmacology analysis of the Huangqi-Gancao herb pair reveals quercetin as a therapeutics for allergic …
Dose: None
vs.: OVA-induced AR mice without treatment
Outcome: Allergic rhinitis symptoms and histopathology
Wirkung: None
None
Population: OVA-induced allergic rhinitis mouse model
In Vitro
Identification of Active Markers of Chinese Formula Yupingfeng San by Network Pharmacology and HPLC-Q-TOF-MS/MS Analysis …
Dose: None
vs.: Allergic rhinitis mouse model vs control
Outcome: Nasal mucosal inflammation and serum markers
Wirkung: None
None
Population: Allergic rhinitis mouse model
Other
A research method of compatibility mechanism of traditional Chinese medicine prescription-taking Yupingfeng San as an …
Dose: None
vs.: Reduced component groups
Outcome: IL-2, IL-4, IGE, TGF-beta levels
Wirkung: None
None
Population: Allergic rhinitis mouse model
Other
Astragalus polysaccharide alleviates IL-13-induced oxidative stress injury in nasal epithelial cells by inhibiting WTAP-mediated FBXW7 …
Dose: None
vs.: None
Outcome: Oxidative stress markers
Wirkung: None
None
Population: None
Key Statistics
3
Studien
200
Teilnehmer
↑
Positive
C
Bewertung
Referenced Papers
Clinica chimica acta; …
2026
Journal of asthma …
2026
Naunyn-Schmiedeberg's archives of …
2025
3 Zitierungen
Pharmaceuticals (Basel, Switzerland)
2025
3 Zitierungen
Journal of ethnopharmacology
2025
Corrigendum to Effect of Astragalus membranaceus in Ovalbumin-Induced Allergic Rhinitis Mouse Model.
Other
American journal of …
2025
Toxicology research
2024
5 Zitierungen
American journal of …
2022
25 Zitierungen
Computational and mathematical …
2022
8 Zitierungen
Journal of medicinal …
2021
32 Zitierungen
Bioengineered
2021
9 Zitierungen
Frontiers in pharmacology
2020
21 Zitierungen
American journal of …
2019
10 Zitierungen
Journal of pharmaceutical …
2017
36 Zitierungen
Molecular medicine reports
2017
21 Zitierungen
[Effect of Astragalus membranaceus on Peripheral Blood Th17 in Patients with Allergic Rhinitis].
Other
Zhongguo Zhong xi …
2016
Journal of ethnopharmacology
2014
12 Zitierungen
A stable fixed-dose combination tablet of pseudoephedrine and KOB extracts for the extended release.
Other
Drug research
2013
4 Zitierungen
Zhong xi yi …
2011
Phytotherapy research : …
2010
61 Zitierungen
Zhong xi yi …
2010
2 Zitierungen
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
Übliche Dosierungen
- general:
- 250-500 mg standardized extract/day
- traditional:
- 9-30 g dried root decoction/day
Obergrenze: No established UL
In der Forschung untersuchte Dosierungen
| Dosierung | Dauer | Wirkung | N |
|---|---|---|---|
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
Beste Einnahmezeit: With meals; traditionally used as a preventive tonic (not during acute illness)
Safety & Side Effects
Gemeldete Nebenwirkungen
- ⚠ Generally well tolerated
- ⚠ Mild gastrointestinal effects (bloating, diarrhea) at high doses
- ⚠ Possible interaction with autoimmune conditions (immunostimulatory)
Bekannte Wechselwirkungen
- ● Immunosuppressant medications (may counteract immunosuppression)
- ● Lithium (may reduce lithium excretion)
- ● Cyclophosphamide (may enhance or interfere with effects)
Tolerierbare Höchstaufnahmemenge: No established UL
Konsultieren Sie immer Ihren Arzt, bevor Sie ein Nahrungsergänzungsmittel einnehmen.Konsultieren Sie immer Ihren Arzt, bevor Sie ein Nahrungsergänzungsmittel einnehmen.
Frequently Asked Questions
Does Astragalus help with Allergic Rhinitis?
Based on 3 studies with 200 participants, there is limited but promising evidence that Astragalus may support Allergic Rhinitis management. Our evidence grade is C (Some Evidence).
How much Astragalus should I take for Allergic Rhinitis?
Studies have used various dosages. A commonly studied range is 250-500 mg standardized extract/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Astragalus?
Reported side effects may include Generally well tolerated, Mild gastrointestinal effects (bloating, diarrhea) at high doses, Possible interaction with autoimmune conditions (immunostimulatory). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Astragalus and Allergic Rhinitis?
We rate the evidence as Grade C (Some Evidence). This rating is based on 3 peer-reviewed studies with 200 total participants. The overall direction of effect is positive.
Related Evidence
Andere Inhaltsstoffe für Allergic Rhinitis
References
- [1] Ning Wang et al.. Clin Chim Acta. 2026. Rebalancing the inflammatory niche in allergic rhinitis ". doi:10.1016/j.cca.2025.120776 PubMed
- [2] Shuang Liu et al.. J Asthma Allergy. 2026. Traditional Chinese Medicine for Allergic Rhinitis: Mechanisms, Evidence, and Gut-Immune Axis Targets. doi:10.2147/JAA.S571460 PubMed
- [3] Yongjun Deng et al.. Naunyn Schmiedebergs Arch Pharmacol. 2025. Network pharmacology analysis of the Huangqi-Gancao herb pair reveals quercetin as a therapeutics for allergic rhinitis via the RELA-regulated IFNG/IRF1 … doi:10.1007/s00210-024-03353-8 PubMed
- [4] Xinqi Li et al.. Pharmaceuticals (Basel). 2025. Identification of Active Markers of Chinese Formula Yupingfeng San by Network Pharmacology and HPLC-Q-TOF-MS/MS Analysis in Experimental Allergic Rhinitis Models … doi:10.3390/ph18040540 PubMed
- [5] Xinyue Li et al.. J Ethnopharmacol. 2025. A research method of compatibility mechanism of traditional Chinese medicine prescription-taking Yupingfeng San as an example. doi:10.1016/j.jep.2025.119815 PubMed
- [6] . Am J Rhinol Allergy. 2025. Corrigendum to Effect of Astragalus membranaceus in Ovalbumin-Induced Allergic Rhinitis Mouse Model. doi:10.1177/1945892420979106 PubMed
- [7] Wei Cui et al.. Toxicol Res (Camb). 2024. Astragalus polysaccharide alleviates IL-13-induced oxidative stress injury in nasal epithelial cells by inhibiting WTAP-mediated FBXW7 m6A modification. doi:10.1093/toxres/tfae099 PubMed
- [8] Xian He et al.. Am J Rhinol Allergy. 2022. Astragalus Polysaccharide Relieves Inflammatory Responses in Guinea Pigs with Allergic Rhinitis via Ameliorating NF-kB-Mediated Treg/Th17 Imbalance. doi:10.1177/19458924221098847 PubMed
- [9] Min Shen et al.. Comput Math Methods Med. 2022. Effect of Traditional Chinese Medicine on Allergic Rhinitis in Children under Data Mining. doi:10.1155/2022/7007370 PubMed
- [10] Jiangtao Xu et al.. J Med Food. 2021. Astragalus Polysaccharides Attenuate Ovalbumin-Induced Allergic Rhinitis in Rats by Inhibiting NLRP3 Inflammasome Activation and NOD2-Mediated NF-κB Activation. doi:10.1089/jmf.2020.4750 PubMed
- [11] Jie Guo et al.. Bioengineered. 2021. Astragaloside IV suppresses histamine-induced inflammatory factors and mucin 5 subtype AC overproduction in nasal epithelial cells via regulation of inflammation-related … doi:10.1080/21655979.2021.1965813 PubMed
- [12] Saisai Wang et al.. Front Pharmacol. 2020. Astragalus Polysaccharides/Chitosan Microspheres for Nasal Delivery: Preparation, Optimization, Characterization, and Pharmacodynamics. doi:10.3389/fphar.2020.00230 PubMed
- [13] Zhong Bing et al.. Am J Rhinol Allergy. 2019. Effect of Astragalus membranaceus in Ovalbumin-Induced Allergic Rhinitis Mouse Model. doi:10.1177/1945892419839259 PubMed
- [14] Stefanie Nikles et al.. J Pharm Biomed Anal. 2017. Metabolic profiling of the traditional Chinese medicine formulation Yu Ping Feng San for the identification of constituents relevant for effects … doi:10.1016/j.jpba.2017.03.049 PubMed
- [15] Keqiong Li et al.. Mol Med Rep. 2017. Protective effects of astragaloside IV against ovalbumin-induced allergic rhinitis are mediated by T-box protein expressed in T cells/GATA-3 and forkhead … doi:10.3892/mmr.2017.6685 PubMed
- [16] Cheng Zhang et al.. Zhongguo Zhong Xi Yi Jie He Za Zhi. 2016. [Effect of Astragalus membranaceus on Peripheral Blood Th17 in Patients with Allergic Rhinitis]. PubMed
- [17] Kuilong Zhou et al.. J Ethnopharmacol. 2014. Qu Feng Xuan Bi Formula attenuates anaphylactic rhinitis-asthma symptoms via reducing EOS count and regulating T cell function in rat … doi:10.1016/j.jep.2014.02.006 PubMed
- [18] C-J Hwang et al.. Drug Res (Stuttg). 2013. A stable fixed-dose combination tablet of pseudoephedrine and KOB extracts for the extended release. doi:10.1055/s-0033-1348222 PubMed
- [19] Jian Cheng et al.. Zhong Xi Yi Jie He Xue Bao. 2011. [Immunoregulatory mechanisms of an optimal Chinese herbal monomer compound in mice with allergic rhinitis]. doi:10.3736/jcim20111213 PubMed
- [20] Zinka Matkovic et al.. Phytother Res. 2010. Efficacy and safety of Astragalus membranaceus in the treatment of patients with seasonal allergic rhinitis. doi:10.1002/ptr.2877 PubMed
- [21] Wei-Yi Gong et al.. Zhong Xi Yi Jie He Xue Bao. 2010. [Optimal combination of baicalin, icariin and Astragalus saponin I from a Chinese herbal compound Biminne]. doi:10.3736/jcim20100606 PubMed
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