What is the recommended dosage for Glutathione?

General: 250-500 mg/day; Immune Support: 500-1,000 mg/day (liposomal preferred)

What are the side effects of Glutathione?

Potential side effects include: Generally well tolerated, Bloating and cramping (oral form), Allergic reactions (rare), Zinc depletion with chronic high-dose use (theoretical).

What is glutathione and how does it support immune health?

Glutathione is the body's primary intracellular antioxidant, critical for lymphocyte function and overall immune defense. Research has explored oral and liposomal glutathione supplementation for maintaining immune cell redox balance and supporting natural killer cell activity.

What dosage of glutathione has been studied in clinical trials?

Clinical studies have used oral glutathione at doses of 250–1,000 mg per day. Liposomal formulations may improve bioavailability compared to standard oral glutathione. Study durations typically range from 4 to 12 weeks.

What are the potential side effects of glutathione supplementation?

Oral glutathione is generally well tolerated. Some individuals may experience bloating, cramping, or allergic reactions. Inhaled glutathione may worsen asthma symptoms. Long-term safety data at high doses is limited.

Glutathione

antioxidant

Also known as: GSH, L-Glutathione, Reduced Glutathione, Liposomal Glutathione

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About

Glutathione (GSH) is the body's master antioxidant tripeptide, critical for optimal function of lymphocytes, NK cells, and macrophages. It maintains cellular redox balance required for immune cell activation, proliferation, and differentiation. Depletion is observed in chronic illness, aging, and oxidative stress conditions.

How It Works

Master antioxidant tripeptide critical for optimal function of lymphocytes, NK cells, and macrophages; maintains cellular redox balance required for immune cell activation, proliferation, and differentiation.

Evidence For Conditions

Condition	Grade	Studies	Participants
Post-Viral Fatigue	D	3	100	View →

Side Effects

Generally well tolerated
Bloating and cramping (oral form)
Allergic reactions (rare)
Zinc depletion with chronic high-dose use (theoretical)

Drug & Supplement Interactions

Chemotherapy agents (may modify oxidative mechanisms; consult oncologist)
Nitroglycerin (may enhance hypotensive effects)

Always inform your healthcare provider about all supplements you take.

Related Ingredients

Astaxanthin Curcumin Quercetin Resveratrol

Quick Facts

Dosage: General: 250-500 mg/day; Immune_Support: 500-1,000 mg/day (liposomal preferred)
Forms: capsule liposomal liquid sublingual tablet powder
Natural Sources: Asparagus, Avocado, Spinach, Okra, Garlic, Walnuts
Upper Limit: No established UL
Best Time: On empty stomach; liposomal forms have superior absorption

Evidence Summary

Post-Viral Fatigue D

FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. The products and information on this website are not intended to diagnose, treat, cure, or prevent any disease. The evidence grades presented are based on our analysis of published peer-reviewed research and do not constitute medical advice. Always consult your healthcare provider before starting any supplement regimen.