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ImmuneCited

Turkey Tail Mushroom ： Immune Aging (Immunosenescence)

C

Phase I dose-escalation trial found 6-9 g/day of turkey tail extract significantly increased CD8+ T cells and CD19+ B cells. Approved as an adjunctive cancer therapy in Japan for decades, supporting its immunomodulatory profile.

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            C

        

        

            
結論

            
            
Phase I dose-escalation trial found 6-9 g/day of turkey tail extract significantly increased CD8+ T cells and CD19+ B cells. Approved as an adjunctive cancer therapy in Japan for decades, supporting its immunomodulatory profile.

            
            
        

    










    

  
Key Study Findings





    

        
        

            

                
                    Review
                
                
                
                
            

            
                Anti-Cancer Potential of Edible/Medicinal Mushrooms in Breast Cancer.
            
            

                
                Dose: Edible/medicinal mushroom extracts
                
                
                vs: None
                
                
                Outcome: Anti-cancer activity in breast cancer
                
                
                効果: None
                
                
                None
                
            

            
            
対象集団: Breast cancer (in vitro/animal review)

            
        

        
    







    
    

        
        

            

  
Key Statistics





            


    

        
3

        
研究数

    

    

        
100

        
参加者数

    

    

        
            
            ↑
            
        
        
Positive

    

    

        C

        
グレード

    




        


        
        
        

            

  
Referenced Papers





            

                
                

                    

                        
                            Anti-Cancer Potential of Edible/Medicinal Mushrooms in Breast Cancer.
                        
                        
                            
                                Review
                            
                            
                            
                        
                    

                    

                        International journal of …
                        2023
                        
                        40 件の引用
                        
                    

                

                
            

        

        

        
        
        

            

  
Dosage & Usage





            
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units


            
            

                
一般的な使用量

                

                    
                    

                        
general:

                        
1-3 g/day

                    

                    
                    

                        
clinical:

                        
3-9 g/day PSK/PSP extract

                    

                    
                

                
                

                    上限量： No established UL
                

                
            

            

            
            

                
研究で検討された用量

                

                    

                        
                            

                                用量
                                期間
                                効果
                                N
                            

                        
                        
                            
                            

                                Edible/medicinal mushroom extracts
                                --
                                
                                    
                                    Positive
                                    
                                
                                --
                            

                            
                        
                    

                

            

            

            
            

                推奨摂取タイミング： With or without food
            

            
        

        

        
        
        

            

  
Safety & Side Effects





            

                
                

                    
報告されている副作用

                    
    
                        
                        
  • 
                            ⚠
                            Gastrointestinal symptoms (bloating, gas, dark stools)
                        
    • 
                        
                        
  • 
                            ⚠
                            Nail darkening (rare)
                        
    • 
                        
                        
  • 
                            ⚠
                            Allergic reactions (rare)
                        
    • 
                        
                    

                

                

                
                

                    
既知の相互作用

                    
    
                        
                        
  • 
                            ●
                            Immunosuppressant medications (may counteract immunosuppression)
                        
    • 
                        
                        
  • 
                            ●
                            Cyclophosphamide (may enhance or modify effects)
                        
    • 
                        
                        
  • 
                            ●
                            Tamoxifen (theoretical interaction)
                        
    • 
                        
                    

                

                

                
                

                    

                        耐容上限摂取量： No established UL
                    

                

                
            

            

                サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。
            

        

        

        
        
        

            

  
Frequently Asked Questions





            




    
    

        
            Does Turkey Tail Mushroom help with Immune Aging (Immunosenescence)?
            
        
        

            Based on 3 studies with 100 participants, there is limited but promising evidence that Turkey Tail Mushroom may support Immune Aging (Immunosenescence) management. Our evidence grade is C (Some Evidence).
        

    

    
    

        
            How much Turkey Tail Mushroom should I take for Immune Aging (Immunosenescence)?
            
        
        

            Studies have used various dosages. A commonly studied range is 1-3 g/day. Always consult your healthcare provider before starting any supplement regimen.
        

    

    
    

        
            Are there side effects of Turkey Tail Mushroom?
            
        
        

            Reported side effects may include Gastrointestinal symptoms (bloating, gas, dark stools), Nail darkening (rare), Allergic reactions (rare). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
        

    

    
    

        
            How strong is the evidence for Turkey Tail Mushroom and Immune Aging (Immunosenescence)?
            
        
        

            We rate the evidence as Grade C (Some Evidence). This rating is based on 3 peer-reviewed studies with 100 total participants. The overall direction of effect is positive.
        

    

    




        

        

        
        
        

            

  
Related Evidence





            

                
                
                

                
            

        

        

    


    
    












    

        FDAに関する免責事項:
        これらの記述は米国食品医薬品局（FDA）による評価を受けていません。本ウェブサイトの製品および情報は、疾病の診断、治療、治癒、または予防を目的としたものではありません。表示されているエビデンスグレードは、公開された査読済み研究の分析に基づいており、医療上の助言を構成するものではありません。サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。