Cordyceps 관련 Immune Aging (Immunosenescence)

Q: Does Cordyceps help with Immune Aging (Immunosenescence)?

Based on 3 studies with 100 participants, there is limited but promising evidence that Cordyceps may support Immune Aging (Immunosenescence) management. Our evidence grade is C (Some Evidence).

Q: How much Cordyceps should I take for Immune Aging (Immunosenescence)?

Studies have used various dosages. A commonly studied range is 1-3 g/day extract. Always consult your healthcare provider before starting any supplement regimen.

Q: Are there side effects of Cordyceps?

Reported side effects may include Mild gastrointestinal discomfort, Dry mouth, Nausea (rare), Potential interaction with autoimmune conditions. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

Q: How strong is the evidence for Cordyceps and Immune Aging (Immunosenescence)?

We rate the evidence as Grade C (Some Evidence). This rating is based on 3 peer-reviewed studies with 100 total participants. The overall direction of effect is positive.

A double-blind randomized controlled trial found Cordyceps mycelium extract showed 38.8% enhancement of NK cell cytotoxic activity after 8 weeks in healthy adults. Supports cell-mediated immunity and may enhance immune surveillance capacity.

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결론

Key Study Findings

Review n=321

Current Evidence of Ergogenic and Post-Exercise Recovery Effects of Dietary Supplementation with Cordyceps militaris in …

Dose: None vs: None Outcome: None 효과: None None

대상 집단: healthy individuals aged 16-35 from 5 intervention studies (2017-2024)

Other

The Inhibitory Effects of Cordyceps militaris ARA301 Extract on Lipopolysaccharide-Induced Lung Injury in vivo.

Dose: None vs: LPS-induced lung injury mouse model vs control Outcome: Immune cell infiltration and inflammatory cytokines 효과: None None

대상 집단: LPS-induced lung injury mouse model

Controlled Clinical Trial n=24 3 weeks

Cordyceps militaris extract and cordycepin ameliorate LPS-challenged colonic damage in piglets by modulating the microbiota …

Dose: 60 mg/kg in basal diet vs: LPS-challenged control (basal diet only) Outcome: Colonic morphology and microbiota composition 효과: None None

대상 집단: Weaned castrated piglets challenged with LPS

Review

Ergogenic Aid by Cordyceps: Does It Work??

Dose: None vs: None Outcome: None 효과: None None

대상 집단: Review of Cordyceps as ergogenic aid in human studies

In Vitro n=24

Transcriptomic and Metabolomic Analyses Reveal the Attenuating Role of Cordycepin and Cordyceps militaris Extract on …

Dose: Cordycepin (CPN) or C. militaris extract (CME) vs: Basal diet + LPS challenge Outcome: Liver injury markers and transcriptome changes 효과: None None

대상 집단: Weaned piglets (4 groups, n=6)

Randomized Controlled Trial 2 weeks Double-blind

Beet supplementation mitigates post-exercise inflammation.

Dose: 212 mg vs: Placebo Outcome: Inflammatory markers 효과: None p < 0.001

대상 집단: None

Key Statistics

연구

100

참여자

↑

Positive

등급

Referenced Papers

Current Evidence of Ergogenic and Post-Exercise Recovery Effects of Dietary Supplementation with Cordyceps militaris in Humans-A Narrative Review. Review

Nutrients 2026

The Inhibitory Effects of Cordyceps militaris ARA301 Extract on Lipopolysaccharide-Induced Lung Injury in vivo. Other

Journal of microbiology … 2025 2 인용

Ergogenic Aid by Cordyceps: Does It Work?? Review

Current nutrition reports 2025 2 인용

Cordyceps militaris extract and cordycepin ameliorate LPS-challenged colonic damage in piglets by modulating the microbiota and metabolite profiles. Other

Frontiers in immunology 2025 1 인용

Beet supplementation mitigates post-exercise inflammation. Other

Frontiers in nutrition 2024 8 인용

Synergistic fermentation of Cordyceps militaris and herbal substrates boosts grower pig antioxidant and immune function. Other

BMC veterinary research 2024 7 인용

Transcriptomic and Metabolomic Analyses Reveal the Attenuating Role of Cordycepin and Cordyceps militaris Extract on Acute Liver Injury Induced by … Other

Animals : an … 2024 1 인용

Anti-Cancer Potential of Edible/Medicinal Mushrooms in Breast Cancer. Review

International journal of … 2023 40 인용

Exploring Edible Mushrooms for Diabetes: Unveiling Their Role in Prevention and Treatment. Review

Molecules (Basel, Switzerland) 2023 40 인용

Medicinal Mushroom Supplements in Cancer: A Systematic Review of Clinical Studies. Systematic Review

Current oncology reports 2023 27 인용

Cordyceps militaris extracts and cordycepin ameliorate type 2 diabetes mellitus by modulating the gut microbiota and metabolites. Other

Frontiers in pharmacology 2023 26 인용

Early Trends to Show the Efficacy of Cordyceps militaris in Mild to Moderate COVID Inflammation. Other

Cureus 2023 5 인용

A Comprehensive Review of Herbal Supplements Used for Persistent Symptoms Attributed to Lyme Disease. Review

Integrative medicine (Encinitas, … 2023 2 인용

Medicinal Fungi with Antiviral Effect. Review

Molecules (Basel, Switzerland) 2022 34 인용

Integrative medicine considerations for convalescence from mild-to-moderate COVID-19 disease. Review

Explore (New York, … 2022 34 인용

Cordycepin for Health and Wellbeing: A Potent Bioactive Metabolite of an Entomopathogenic Cordyceps Medicinal Fungus and Its Nutraceutical and Therapeutic … Review

Molecules (Basel, Switzerland) 2020 153 인용

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

일반적으로 사용되는 용량

general:: 1-3 g/day extract
immunesupport:: 1,000-3,000 mg standardized extract/day

상한량: No established UL

연구에서 사용된 용량

용량	기간	효과	N
None	--	Mixed	321
None	--	Positive	--
60 mg/kg in basal diet	3 weeks	Positive	24
None	--	Mixed	--
Cordycepin (CPN) or C. militaris extract (CME)	--	Positive	24
212 mg	2 weeks	Neutral	--
None	--	Positive	--
Mushroom extracts (various species)	--	Positive	--

권장 복용 시간: Morning or early afternoon; with or without food

Safety & Side Effects

보고된 부작용

⚠ Mild gastrointestinal discomfort
⚠ Dry mouth
⚠ Nausea (rare)
⚠ Potential interaction with autoimmune conditions

알려진 상호작용

● Immunosuppressant medications (may counteract immunosuppression)
● Anticoagulants (may increase bleeding risk)
● Diabetes medications (may enhance blood sugar lowering)

일일 최대 섭취 허용량: No established UL

건강기능식품을 복용하기 전에 반드시 의료 전문가와 상담하십시오.

Frequently Asked Questions

Does Cordyceps help with Immune Aging (Immunosenescence)?

Based on 3 studies with 100 participants, there is limited but promising evidence that Cordyceps may support Immune Aging (Immunosenescence) management. Our evidence grade is C (Some Evidence).

How much Cordyceps should I take for Immune Aging (Immunosenescence)?

Studies have used various dosages. A commonly studied range is 1-3 g/day extract. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Cordyceps?

Reported side effects may include Mild gastrointestinal discomfort, Dry mouth, Nausea (rare), Potential interaction with autoimmune conditions. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Cordyceps and Immune Aging (Immunosenescence)?

We rate the evidence as Grade C (Some Evidence). This rating is based on 3 peer-reviewed studies with 100 total participants. The overall direction of effect is positive.

Related Evidence

한눈에 보기

Evidence Strength52%

Moderate confidence

연구 분석

RCT (0)Meta (0)Other (3)

대안 비교

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모든 성분 보기: Immune Aging (Immunosenescence)

자세히 알아보기

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