What are the side effects of Conjugated Linoleic Acid?

Potential side effects include: Gastrointestinal discomfort (nausea, diarrhea), Fatigue, May worsen insulin sensitivity in some individuals, Liver fat accumulation (some formulations).

What is CLA and how does it relate to immune function?

Conjugated linoleic acid (CLA) is a group of fatty acids found naturally in meat and dairy. Some research suggests CLA may modulate inflammatory immune responses and influence cytokine production, though evidence for direct immune benefits remains preliminary.

What dosage of CLA has been studied in clinical trials?

Clinical studies have used CLA doses of 1.5–6 g per day, with 3–4 g being the most common range. Studies examining immune-related outcomes have typically lasted 8 to 12 weeks.

What are the potential side effects of CLA?

Common side effects include gastrointestinal discomfort, nausea, and loose stools. Some studies have raised concerns about CLA's effects on insulin sensitivity and liver fat accumulation at higher doses. Consult a healthcare provider before long-term use.

Conjugated Linoleic Acid
Conjugated Linoleic Acid

fatty_acid

다른 이름: CLA

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About

Conjugated linoleic acid (CLA) modulates immune cell membrane composition and eicosanoid production. It influences PPAR-gamma activation which regulates inflammatory gene expression and may support balanced Th1/Th2 immune responses. Human evidence for immune-specific outcomes remains limited and inconsistent.

How It Works

Modulates immune cell membrane composition and eicosanoid production; influences PPAR-gamma activation regulating inflammatory gene expression; may support balanced Th1/Th2 immune responses.

Evidence For Conditions

건강 상태	등급	연구	참여자
Chronic Inflammation	D	3	150	보기 →

Side Effects

Gastrointestinal discomfort (nausea, diarrhea)
Fatigue
May worsen insulin sensitivity in some individuals
Liver fat accumulation (some formulations)

Drug & Supplement Interactions

Diabetes medications (may affect insulin sensitivity)
Anticoagulants (may have additive effects)

복용 중인 모든 건강기능식품에 대해 반드시 의료 전문가에게 알리십시오.

Related Ingredients

Omega-3 Fatty Acids (EPA/DHA)

핵심 정보

용량: General: 1.5-3 g/day
제형: softgel capsule
천연 원료: Grass-fed beef, Lamb, Full-fat dairy, Cheese
상한 섭취량: No established UL
권장 복용 시간: With meals

근거 요약

Chronic Inflammation D

FDA 면책 조항: 이 내용은 미국 식품의약국(FDA)의 평가를 받지 않았습니다. 이 웹사이트의 제품 및 정보는 질병의 진단, 치료, 완치 또는 예방을 목적으로 하지 않습니다. 제시된 근거 등급은 발표된 동료 심사 연구에 대한 우리의 분석에 기반하며, 의학적 조언을 구성하지 않습니다. 건강기능식품 복용을 시작하기 전에 반드시 의료 전문가와 상담하십시오.