Arginine methylation in the epithelial-to-mesenchymal transition.
Study Design
- Loại nghiên cứu
- Review
- Đối tượng nghiên cứu
- None
- Can thiệp
- Arginine methylation in the epithelial-to-mesenchymal transition. None
- Đối chứng
- None
- Kết quả chính
- None
- Xu hướng hiệu quả
- Mixed
- Nguy cơ sai lệch
- Unclear
Abstract
Epithelial cells acquire mesenchymal characteristics during embryonic development, wound healing, fibrosis, and in cancer in a processed termed epithelial-to-mesenchymal transition (EMT). Regulatory networks of EMT are controlled by post-transcriptional, translational, and post-translational mechanisms, in which arginine methylation is critically involved. Here, we review arginine methylation-dependent mechanisms that regulate EMT in the aspects of signaling, transcriptional, and splicing regulation.
Tóm lược
Arginine methylation‐dependent mechanisms that regulate EMT in the aspects of signaling, transcriptional, and splicing regulation are reviewed.
Used In Evidence Reviews
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