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ImmuneCited

Vitamin D
Vitamin D

vitamin

别名: Cholecalciferol, Vitamin D3, Ergocalciferol, Calciferol

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About





            

                
Vitamin D is a fat-soluble secosteroid hormone that modulates both innate and adaptive immune responses. It maintains epithelial barrier integrity, boosts production of antimicrobial peptides (cathelicidin LL-37 and defensins), and regulates T-cell and macrophage function. The VITAL trial demonstrated a 22% reduction in autoimmune disease risk with supplementation.

            

        

        

        
        
        

            

  
How It Works





            

                
Modulates both innate and adaptive immune responses by maintaining epithelial barrier integrity and boosting production of antimicrobial peptides (cathelicidin LL-37 and defensins); regulates T-cell and macrophage function.

            

        

        

        
        
        

            

  
Evidence For Conditions





            

                

                    

                        
                            

                                健康状况
                                等级
                                研究数量
                                受试者
                                
                            

                        
                        
                            
                            

                                
                                    
                                        Upper Respiratory Tract Infections
                                    
                                
                                
                                    A

                                
                                
                                    40
                                
                                
                                    30000
                                
                                
                                    
                                        查看 →
                                    
                                
                            

                            
                            

                                
                                    
                                        Autoimmune Conditions
                                    
                                
                                
                                    A

                                
                                
                                    3
                                
                                
                                    25871
                                
                                
                                    
                                        查看 →
                                    
                                
                            

                            
                            

                                
                                    
                                        Immune Aging (Immunosenescence)
                                    
                                
                                
                                    B

                                
                                
                                    10
                                
                                
                                    5000
                                
                                
                                    
                                        查看 →
                                    
                                
                            

                            
                        
                    

                

            

        

        

        
        
        

            

  
Side Effects





            
    
                
                
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                    Hypercalcemia at very high doses (nausea, vomiting, weakness)
                
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                    Kidney stones with excessive long-term use
                
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                    Constipation
                
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                    Metallic taste
                
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Drug & Supplement Interactions





            
    
                
                
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                    Thiazide diuretics (may increase risk of hypercalcemia)
                
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                    Corticosteroids (reduce vitamin D absorption and metabolism)
                
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                    Orlistat and cholestyramine (reduce fat-soluble vitamin absorption)
                
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                    Statins (vitamin D may affect statin metabolism)
                
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                请务必告知您的医疗保健提供者您正在服用的所有补充剂。
            

        

        

        
        
        

            

  
Related Ingredients





            

                
                
                    Vitamin B6
                    
                
                
                
                    Vitamin C
                    
                
                
                
                    Vitamin A
                    
                
                
                
                    Vitamin E
                    
                
                
            

        

        
    


    
    












    

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