What is the recommended dosage for Vitamin E?

General: 15 mg/day (22.4 IU); Immune Support Elderly: 200 IU/day

What are the side effects of Vitamin E?

Potential side effects include: Increased bleeding risk at high doses (>400 IU/day), Nausea and gastrointestinal distress, Fatigue and muscle weakness at very high doses, Potential increased mortality risk at chronic high doses (meta-analysis finding, debated).

What is vitamin E and how does it relate to immune function?

Vitamin E is a fat-soluble antioxidant that protects immune cell membranes from oxidative damage. Clinical studies, particularly in older adults, have examined its potential to enhance T-cell function and improve vaccine responses.

What dosage of vitamin E has been studied for immune support?

Studies have used alpha-tocopherol at doses of 200–800 IU per day for immune outcomes in older adults. The SENIEUR protocol studies used 200 mg per day, which appeared to enhance delayed-type hypersensitivity responses. The Tolerable Upper Intake Level is 1,000 mg per day.

What are the potential side effects of vitamin E supplementation?

High-dose vitamin E may increase bleeding risk, particularly in combination with anticoagulant medications. Some large trials have raised concerns about cardiovascular risk at doses above 400 IU per day. Supplementation should be discussed with a healthcare provider.

Vitamin E
Vitamin E

vitamin

También conocido como: Alpha-Tocopherol, d-Alpha-Tocopherol, Mixed Tocopherols

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About

Vitamin E is a potent lipid-soluble antioxidant that protects immune cell membranes from oxidative damage. It enhances T-cell proliferation, lymphocyte function, and natural killer cell activity, particularly in older adults. Clinical trials in elderly populations show supplementation at 200 IU/day enhances DTH skin test response and antibody production.

How It Works

Potent lipid-soluble antioxidant that protects immune cell membranes from oxidative damage; enhances T-cell proliferation, lymphocyte function, and natural killer cell activity.

Evidence For Conditions

Condición	Calificación	Estudios	Participantes
Immune Aging (Immunosenescence)	B	5	600	Ver →

Side Effects

Increased bleeding risk at high doses (>400 IU/day)
Nausea and gastrointestinal distress
Fatigue and muscle weakness at very high doses
Potential increased mortality risk at chronic high doses (meta-analysis finding, debated)

Drug & Supplement Interactions

Anticoagulants and antiplatelet drugs (increased bleeding risk)
Statins (may reduce statin effectiveness)
Chemotherapy agents (may interfere with oxidative mechanisms)
Vitamin K (high-dose vitamin E may antagonize vitamin K)

Informe siempre a su profesional de salud sobre todos los suplementos que toma.Siempre informe a su profesional de salud sobre todos los suplementos que toma.

Related Ingredients

Vitamin D Vitamin B6 Vitamin C Vitamin A

Datos rápidos

Dosificación: General: 15 mg/day (22.4 IU); Immune_Support_Elderly: 200 IU/day
Formas: capsule softgel liquid
Fuentes naturales: Sunflower seeds, Almonds, Hazelnuts, Wheat germ oil, Spinach
Límite superior: 1,000 mg/day (1,500 IU natural, 1,100 IU synthetic)
Mejor momento: With meals containing fat

Resumen de evidencia

Immune Aging (Immunosenescence) B

Aviso legal FDA: Estas declaraciones no han sido evaluadas por la Food and Drug Administration. Los productos y la información en este sitio web no están destinados a diagnosticar, tratar, curar ni prevenir ninguna enfermedad. Las calificaciones de evidencia presentadas se basan en nuestro análisis de investigación publicada revisada por pares y no constituyen consejo médico. Siempre consulte a su profesional de salud antes de comenzar cualquier régimen de suplementos.