Andrographis for Upper Respiratory Tract Infections
BMultiple randomized controlled trials and Cochrane-reviewed meta-analyses support andrographis for reducing the severity and duration of upper respiratory symptoms. One of the most evidence-backed herbal supplements for acute respiratory infections.
The Bottom Line
Multiple randomized controlled trials and Cochrane-reviewed meta-analyses support andrographis for reducing the severity and duration of upper respiratory symptoms. One of the most evidence-backed herbal supplements for acute respiratory infections.
Key Study Findings
Population: Participants with uncomplicated URTI
Population: COVID-19/URTI patients
Population: None
Population: None
Population: upper respiratory tract infection
Population: None
Key Statistics
7
Studies
800
Participants
Positive
Grade
Referenced Papers
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
Commonly Used Dosages
- acute:
- 400 mg 3x/day for up to 7 days
- general:
- 200 mg standardized extract (30% andrographolides) 2x/day
Upper limit: No established UL; short-term use (<14 days)
Dosages Studied in Research
| Dosage | Duration | Effect | N |
|---|---|---|---|
| 200 mg/day | 1.0 weeks | Positive | 331 |
| None | -- | Positive | -- |
| None | -- | Mixed | -- |
| 60 mg | -- | Positive | 179 |
| 95% | -- | Neutral | 1000 |
| 6 μg/mL | -- | Positive | -- |
| None | -- | Mixed | -- |
| 18 G | 4.0 weeks | Mixed | -- |
Best taken: At first sign of symptoms; with meals
Safety & Side Effects
Reported Side Effects
- ⚠ Gastrointestinal discomfort (nausea, diarrhea)
- ⚠ Headache
- ⚠ Fatigue
- ⚠ Allergic reactions (rare)
- ⚠ Potential anti-fertility effects (high doses in animal studies)
Known Interactions
- ● Anticoagulant and antiplatelet drugs (may increase bleeding risk)
- ● Antihypertensive medications (additive blood pressure lowering)
- ● Immunosuppressant medications (may counteract immunosuppression)
Tolerable upper intake: No established UL; short-term use (<14 days)
Always consult your healthcare provider before starting any supplement.
Frequently Asked Questions
Does Andrographis help with Upper Respiratory Tract Infections?
How much Andrographis should I take for Upper Respiratory Tract Infections?
Are there side effects of Andrographis?
How strong is the evidence for Andrographis and Upper Respiratory Tract Infections?
Related Evidence
Other ingredients for Upper Respiratory Tract Infections
FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. The products and information on this website are not intended to diagnose, treat, cure, or prevent any disease. The evidence grades presented are based on our analysis of published peer-reviewed research and do not constitute medical advice. Always consult your healthcare provider before starting any supplement regimen.