Andrographis для Upper Respiratory Tract Infections

Q: Does Andrographis help with Upper Respiratory Tract Infections?

Based on 7 studies with 800 participants, there is moderate evidence from clinical studies that Andrographis may support Upper Respiratory Tract Infections management. Our evidence grade is B (Good Evidence).

Q: How much Andrographis should I take for Upper Respiratory Tract Infections?

Studies have used various dosages. A commonly studied range is 400 mg 3x/day for up to 7 days. Always consult your healthcare provider before starting any supplement regimen.

Q: Are there side effects of Andrographis?

Reported side effects may include Gastrointestinal discomfort (nausea, diarrhea), Headache, Fatigue, Allergic reactions (rare). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

Q: How strong is the evidence for Andrographis and Upper Respiratory Tract Infections?

We rate the evidence as Grade B (Good Evidence). This rating is based on 7 peer-reviewed studies with 800 total participants. The overall direction of effect is positive.

Multiple randomized controlled trials and Cochrane-reviewed meta-analyses support andrographis for reducing the severity and duration of upper respiratory symptoms. One of the most evidence-backed herbal supplements for acute respiratory infections.

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Итог

Key Study Findings

Randomized Controlled Trial n=331 1.0 weeks Double-blind

Efficacy and safety of AP-Bio®(KalmCold®) in participants with uncomplicated upper respiratory tract viral infection (common …

Dose: 200 mg/day или: placebo Outcome: URTI symptom severity Эффект: None p = 0.034

Популяция: Participants with uncomplicated URTI

Review

A Comprehensive Review of Andrographis paniculata (Burm. f.) Nees and Its Constituents as Potential Lead …

Dose: None или: None Outcome: URTI symptom severity Эффект: None None

Популяция: COVID-19/URTI patients

Review

Plant-Based Support of Respiratory Health during Viral Outbreaks.

Dose: None или: None Outcome: None Эффект: None None

Популяция: None

Other n=179

Early intervention with Kan Jang® to treat upper-respiratory tract infections: A randomized, quadruple-blind study.

Dose: 60 mg или: placebo Outcome: None Эффект: None p = 0.0053

Популяция: None

Meta-Analysis n=1000

Safety of Andrographis paniculata: A systematic review and meta-analysis.

Dose: 95% или: control Outcome: None Эффект: None None

Популяция: upper respiratory tract infection

Other

In vitro anti-biofilm activity of 14-deoxy-11,12-didehydroandrographolide from Andrographis paniculata against Pseudomonas aeruginosa.

Dose: 6 μg/mL или: Control group Outcome: None Эффект: None None

Популяция: None

Key Statistics

Исследования

800

Участники

↑

Positive

Оценка

Referenced Papers

Efficacy and safety of AP-Bio®(KalmCold®) in participants with uncomplicated upper respiratory tract viral infection (common cold) - A phase III, … RCT

Complementary therapies in … 2023 6 цитирований

A Comprehensive Review of Andrographis paniculata (Burm. f.) Nees and Its Constituents as Potential Lead Compounds for COVID-19 Drug Discovery. Review

Molecules (Basel, Switzerland) 2022 80 цитирований

Plant-Based Support of Respiratory Health during Viral Outbreaks. Other

Journal of agricultural … 2022 9 цитирований

Safety of Andrographis paniculata: A systematic review and meta-analysis. Meta-Analysis

Pharmacoepidemiology and drug … 2021 32 цитирований

Early intervention with Kan Jang® to treat upper-respiratory tract infections: A randomized, quadruple-blind study. Other

Journal of traditional … 2021 9 цитирований

In vitro anti-biofilm activity of 14-deoxy-11,12-didehydroandrographolide from Andrographis paniculata against Pseudomonas aeruginosa. Other

Brazilian journal of … 2020 45 цитирований

Inhibition of AIM2 inflammasome-mediated pyroptosis by Andrographolide contributes to amelioration of radiation-induced lung inflammation and fibrosis. Other

Cell death & … 2019 160 цитирований

A review for the neuroprotective effects of andrographolide in the central nervous system. Review

Biomedicine & pharmacotherapy … 2019 103 цитирований

A randomized double blind placebo controlled clinical evaluation of extract of Andrographis paniculata (KalmCold) in patients with uncomplicated upper respiratory … RCT

Phytomedicine : international … 2010 107 цитирований

Colds and influenza: a review of diagnosis and conventional, botanical, and nutritional considerations. Review

Alternative medicine review … 2007 163 цитирований

Complementary and alternative medicine for upper-respiratory-tract infection in children. Review

American journal of … 2006 51 цитирований

Andrographis paniculata in the treatment of upper respiratory tract infections: a systematic review of safety and efficacy. Systematic Review

Planta medica 2004 262 цитирований

Andrographis paniculata in the symptomatic treatment of uncomplicated upper respiratory tract infection: systematic review of randomized controlled trials. Systematic Review

Journal of clinical … 2004 157 цитирований

Respiratory and allergic diseases: from upper respiratory tract infections to asthma. Review

Primary care 2002 56 цитирований

Undetectable anti-bacterial activity of Andrographis paniculata (Burma) wall. ex ness. RCT

Journal of the … 1990

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Часто используемые дозировки

acute:: 400 mg 3x/day for up to 7 days
general:: 200 mg standardized extract (30% andrographolides) 2x/day

Верхний предел: No established UL; short-term use (<14 days)

Дозировки, изученные в исследованиях

Дозировка	Длительность	Эффект	N
200 mg/day	1.0 weeks	Positive	331
None	--	Positive	--
None	--	Mixed	--
60 mg	--	Positive	179
95%	--	Neutral	1000
6 μg/mL	--	Positive	--
None	--	Mixed	--
18 G	4.0 weeks	Mixed	--

Лучшее время приёма: At first sign of symptoms; with meals

Safety & Side Effects

Зарегистрированные побочные эффекты

⚠ Gastrointestinal discomfort (nausea, diarrhea)
⚠ Headache
⚠ Fatigue
⚠ Allergic reactions (rare)
⚠ Potential anti-fertility effects (high doses in animal studies)

Известные взаимодействия

● Anticoagulant and antiplatelet drugs (may increase bleeding risk)
● Antihypertensive medications (additive blood pressure lowering)
● Immunosuppressant medications (may counteract immunosuppression)

Допустимый верхний уровень потребления: No established UL; short-term use (<14 days)

Всегда консультируйтесь с врачом перед началом приёма любых добавок.Всегда консультируйтесь с лечащим врачом перед началом приёма любой добавки.

Frequently Asked Questions

Does Andrographis help with Upper Respiratory Tract Infections?

Based on 7 studies with 800 participants, there is moderate evidence from clinical studies that Andrographis may support Upper Respiratory Tract Infections management. Our evidence grade is B (Good Evidence).

How much Andrographis should I take for Upper Respiratory Tract Infections?

Studies have used various dosages. A commonly studied range is 400 mg 3x/day for up to 7 days. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Andrographis?

Reported side effects may include Gastrointestinal discomfort (nausea, diarrhea), Headache, Fatigue, Allergic reactions (rare). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Andrographis and Upper Respiratory Tract Infections?

We rate the evidence as Grade B (Good Evidence). This rating is based on 7 peer-reviewed studies with 800 total participants. The overall direction of effect is positive.

Related Evidence

Другие ингредиенты для Upper Respiratory Tract Infections

Vitamin D A Zinc A Beta-Glucan A Vitamin C B Echinacea B Garlic B

Краткий вывод

Evidence Strength72%

High confidence

Разбор исследований

RCT (3)Meta (1)Other (3)

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