Vitamin C для Upper Respiratory Tract Infections
B Доказательства По меньшей мере одно рандомизированное исследование подтверждает это, с в целом согласованными результатами.Research suggests regular vitamin C supplementation may reduce cold duration by approximately 8% in adults and 14% in children. Supplementation at 1g+/day is associated with reduced severity of cold symptoms. Notably, vitamin C started after symptom onset does not appear to be effective.
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B
Итог
Research suggests regular vitamin C supplementation may reduce cold duration by approximately 8% in adults and 14% in children. Supplementation at 1g+/day is associated with reduced severity of cold symptoms. Notably, vitamin C started after symptom onset does not appear to be effective.
Key Study Findings
Review
UCI Sports Nutrition Project: The Role of Nutrition in the Prevention and Management of Illnesses …
Dose: None
или: None
Outcome: None
Эффект: None
None
Популяция: Elite/professional cyclists nutrition review
Review
Micronutrient Deficiencies in Pediatric IBD: How Often, Why, and What to Do?
Dose: None
или: None
Outcome: Micronutrient deficiency management in pediatric IBD
Эффект: None
None
Популяция: Children with inflammatory bowel disease (review)
Other
Circulating micronutrient levels and respiratory infection susceptibility and severity: a bidirectional Mendelian randomization analysis.
Dose: 12 circulating micronutrients
или: Genetic instrument comparison
Outcome: URTI, LRTI, pneumonia risk
Эффект: None
None
Популяция: Large genetic cohort (MR analysis)
Review
Nutraceuticals and pharmacological to balance the transitional microbiome to extend immunity during COVID-19 and other …
Dose: Probiotics, nutraceuticals
или: None
Outcome: Immune response modulation in COVID-19
Эффект: None
None
Популяция: COVID-19 patients with gut dysbiosis
Randomized Controlled Trial
Zinc and L-Ascorbic Acid Dietary Supplementation Affected Antioxidant Status, Heat Shock Protein 70, and Some …
Dose: None
или: Basal diet without supplementation
Outcome: Antioxidant status, hematology, growth in broilers
Эффект: None
None
Популяция: Broiler chickens
Randomized Controlled Trial
n=171
24 weeks
Double-blind
Probiotics with vitamin C for the prevention of upper respiratory tract symptoms in children aged …
Dose: 12.5 billion cfu/d
или: placebo
Outcome: None
Эффект: or 6
P=0.0300
Популяция: None
Key Statistics
30
Исследования
10000
Участники
↑
Positive
B
Оценка
Referenced Papers
Nutrients
2025
4 цитирований
International journal of …
2025
2 цитирований
Journal of translational …
2024
2 цитирований
Frontiers in nutrition
2024
1 цитирований
Biological trace element …
2022
5 цитирований
Beneficial microbes
2021
18 цитирований
European journal of …
2021
Nutrients
2020
75 цитирований
Efficacy of vitamin C for the prevention and treatment of upper respiratory tract infection. A meta-analysis in children.
Meta-Analysis
European journal of …
2019
54 цитирований
Journal of evidence-based …
2017
134 цитирований
European journal of …
2017
18 цитирований
Zhongguo Zhong yao …
2017
European journal of …
2015
70 цитирований
World journal of …
2015
62 цитирований
Zhongguo Zhong yao …
2014
4 цитирований
Zhongguo Zhong yao …
2013
European journal of …
2012
225 цитирований
The British journal …
2012
40 цитирований
American family physician
2012
Journal of the …
2011
8 цитирований
International journal of …
2008
11 цитирований
American journal of …
2006
51 цитирований
Clinical evidence
2003
Clinical evidence
2003
The British journal …
2002
358 цитирований
Primary care
2002
56 цитирований
American family physician
2002
Canadian journal of …
2001
72 цитирований
Medicine and science …
2000
262 цитирований
Medicine and science …
2000
248 цитирований
Alternative medicine review …
2000
Canadian journal of …
1998
41 цитирований
Journal of applied …
1997
434 цитирований
International journal of …
1997
167 цитирований
Exercise immunology review
1997
27 цитирований
Respiration; international review …
1989
25 цитирований
Scandinavian journal of …
1977
56 цитирований
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
Часто используемые дозировки
- general:
- 75-90 mg/day
- acuteillness:
- 1,000-2,000 mg/day
- immunesupport:
- 200-1,000 mg/day
Верхний предел: 2,000 mg/day
Дозировки, изученные в исследованиях
| Дозировка | Длительность | Эффект | N |
|---|---|---|---|
| None | -- | Mixed | -- |
| None | -- | Neutral | -- |
| 12 circulating micronutrients | -- | Mixed | -- |
| Probiotics, nutraceuticals | -- | Positive | -- |
| None | -- | Positive | -- |
| 12.5 billion cfu/d | 24 weeks | Mixed | 171 |
| 45% | 988 weeks | Positive | 26282 |
| None | 13.0 weeks | Mixed | 3135 |
Лучшее время приёма: With meals; divide doses >500 mg for better absorption
Safety & Side Effects
Зарегистрированные побочные эффекты
- ⚠ Gastrointestinal distress (nausea, diarrhea, cramps) at high doses
- ⚠ Increased risk of kidney stones in susceptible individuals
- ⚠ Interference with certain lab tests (glucose, occult blood)
- ⚠ Iron overload risk in hemochromatosis patients
Известные взаимодействия
- ● Enhances non-heme iron absorption (beneficial or harmful depending on iron status)
- ● High doses may reduce effectiveness of certain chemotherapy agents
- ● May interfere with anticoagulant therapy (warfarin) at high doses
- ● Aluminum-containing antacids (increased aluminum absorption)
Допустимый верхний уровень потребления: 2,000 mg/day
Всегда консультируйтесь с врачом перед началом приёма любых добавок.Всегда консультируйтесь с лечащим врачом перед началом приёма любой добавки.
Frequently Asked Questions
Does Vitamin C help with Upper Respiratory Tract Infections?
Based on 30 studies with 10,000 participants, there is moderate evidence from clinical studies that Vitamin C may support Upper Respiratory Tract Infections management. Our evidence grade is B (Good Evidence).
How much Vitamin C should I take for Upper Respiratory Tract Infections?
Studies have used various dosages. A commonly studied range is 75-90 mg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Vitamin C?
Reported side effects may include Gastrointestinal distress (nausea, diarrhea, cramps) at high doses, Increased risk of kidney stones in susceptible individuals, Interference with certain lab tests (glucose, occult blood), Iron overload risk in hemochromatosis patients. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Vitamin C and Upper Respiratory Tract Infections?
We rate the evidence as Grade B (Good Evidence). This rating is based on 30 peer-reviewed studies with 10,000 total participants. The overall direction of effect is positive.
Related Evidence
Другие ингредиенты для Upper Respiratory Tract Infections
Vitamin C для других состояний
References
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