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Vitamin C für Upper Respiratory Tract Infections

B

Research suggests regular vitamin C supplementation may reduce cold duration by approximately 8% in adults and 14% in children. Supplementation at 1g+/day is associated with reduced severity of cold symptoms. Notably, vitamin C started after symptom onset does not appear to be effective.

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Fazit

Research suggests regular vitamin C supplementation may reduce cold duration by approximately 8% in adults and 14% in children. Supplementation at 1g+/day is associated with reduced severity of cold symptoms. Notably, vitamin C started after symptom onset does not appear to be effective.

Key Study Findings

Review
UCI Sports Nutrition Project: The Role of Nutrition in the Prevention and Management of Illnesses …
Dose: None vs.: None Outcome: None Wirkung: None None

Population: Elite/professional cyclists nutrition review

Review
Micronutrient Deficiencies in Pediatric IBD: How Often, Why, and What to Do?
Dose: None vs.: None Outcome: Micronutrient deficiency management in pediatric IBD Wirkung: None None

Population: Children with inflammatory bowel disease (review)

Other
Circulating micronutrient levels and respiratory infection susceptibility and severity: a bidirectional Mendelian randomization analysis.
Dose: 12 circulating micronutrients vs.: Genetic instrument comparison Outcome: URTI, LRTI, pneumonia risk Wirkung: None None

Population: Large genetic cohort (MR analysis)

Review
Nutraceuticals and pharmacological to balance the transitional microbiome to extend immunity during COVID-19 and other …
Dose: Probiotics, nutraceuticals vs.: None Outcome: Immune response modulation in COVID-19 Wirkung: None None

Population: COVID-19 patients with gut dysbiosis

Randomized Controlled Trial
Zinc and L-Ascorbic Acid Dietary Supplementation Affected Antioxidant Status, Heat Shock Protein 70, and Some …
Dose: None vs.: Basal diet without supplementation Outcome: Antioxidant status, hematology, growth in broilers Wirkung: None None

Population: Broiler chickens

Randomized Controlled Trial n=171 24 weeks Double-blind
Probiotics with vitamin C for the prevention of upper respiratory tract symptoms in children aged …
Dose: 12.5 billion cfu/d vs.: placebo Outcome: None Wirkung: or 6 P=0.0300

Population: None

Key Statistics

30

Studien

10000

Teilnehmer

Positive

B

Bewertung

Referenced Papers

World journal of … 2015 62 Zitierungen
European journal of … 2012 225 Zitierungen
American family physician 2012
Clinical evidence 2003
Clinical evidence 2003
The British journal … 2002 358 Zitierungen
American family physician 2002
Canadian journal of … 2001 72 Zitierungen
Medicine and science … 2000 262 Zitierungen
Medicine and science … 2000 248 Zitierungen
Alternative medicine review … 2000
Canadian journal of … 1998 41 Zitierungen
Journal of applied … 1997 434 Zitierungen
International journal of … 1997 167 Zitierungen
Respiration; international review … 1989 25 Zitierungen
Scandinavian journal of … 1977 56 Zitierungen

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Übliche Dosierungen

general:
75-90 mg/day
acuteillness:
1,000-2,000 mg/day
immunesupport:
200-1,000 mg/day

Obergrenze: 2,000 mg/day

In der Forschung untersuchte Dosierungen

Dosierung Dauer Wirkung N
None -- Mixed --
None -- Neutral --
12 circulating micronutrients -- Mixed --
Probiotics, nutraceuticals -- Positive --
None -- Positive --
12.5 billion cfu/d 24 weeks Mixed 171
45% 988 weeks Positive 26282
None 13.0 weeks Mixed 3135

Beste Einnahmezeit: With meals; divide doses >500 mg for better absorption

Safety & Side Effects

Gemeldete Nebenwirkungen

  • Gastrointestinal distress (nausea, diarrhea, cramps) at high doses
  • Increased risk of kidney stones in susceptible individuals
  • Interference with certain lab tests (glucose, occult blood)
  • Iron overload risk in hemochromatosis patients

Bekannte Wechselwirkungen

  • Enhances non-heme iron absorption (beneficial or harmful depending on iron status)
  • High doses may reduce effectiveness of certain chemotherapy agents
  • May interfere with anticoagulant therapy (warfarin) at high doses
  • Aluminum-containing antacids (increased aluminum absorption)

Tolerierbare Höchstaufnahmemenge: 2,000 mg/day

Konsultieren Sie immer Ihren Arzt, bevor Sie ein Nahrungsergänzungsmittel einnehmen.Konsultieren Sie immer Ihren Arzt, bevor Sie ein Nahrungsergänzungsmittel einnehmen.

Frequently Asked Questions

Does Vitamin C help with Upper Respiratory Tract Infections?
Based on 30 studies with 10,000 participants, there is moderate evidence from clinical studies that Vitamin C may support Upper Respiratory Tract Infections management. Our evidence grade is B (Good Evidence).
How much Vitamin C should I take for Upper Respiratory Tract Infections?
Studies have used various dosages. A commonly studied range is 75-90 mg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Vitamin C?
Reported side effects may include Gastrointestinal distress (nausea, diarrhea, cramps) at high doses, Increased risk of kidney stones in susceptible individuals, Interference with certain lab tests (glucose, occult blood), Iron overload risk in hemochromatosis patients. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Vitamin C and Upper Respiratory Tract Infections?
We rate the evidence as Grade B (Good Evidence). This rating is based on 30 peer-reviewed studies with 10,000 total participants. The overall direction of effect is positive.

Related Evidence

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