Vitamin C cho Upper Respiratory Tract Infections
B Bằng chứng Ít nhất một thử nghiệm ngẫu nhiên ủng hộ điều này, với các kết quả phần lớn nhất quán.Research suggests regular vitamin C supplementation may reduce cold duration by approximately 8% in adults and 14% in children. Supplementation at 1g+/day is associated with reduced severity of cold symptoms. Notably, vitamin C started after symptom onset does not appear to be effective.
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B
Kết luận
Research suggests regular vitamin C supplementation may reduce cold duration by approximately 8% in adults and 14% in children. Supplementation at 1g+/day is associated with reduced severity of cold symptoms. Notably, vitamin C started after symptom onset does not appear to be effective.
Key Study Findings
Review
UCI Sports Nutrition Project: The Role of Nutrition in the Prevention and Management of Illnesses …
Dose: None
so với: None
Outcome: None
Hiệu quả: None
None
Đối tượng nghiên cứu: Elite/professional cyclists nutrition review
Review
Micronutrient Deficiencies in Pediatric IBD: How Often, Why, and What to Do?
Dose: None
so với: None
Outcome: Micronutrient deficiency management in pediatric IBD
Hiệu quả: None
None
Đối tượng nghiên cứu: Children with inflammatory bowel disease (review)
Other
Circulating micronutrient levels and respiratory infection susceptibility and severity: a bidirectional Mendelian randomization analysis.
Dose: 12 circulating micronutrients
so với: Genetic instrument comparison
Outcome: URTI, LRTI, pneumonia risk
Hiệu quả: None
None
Đối tượng nghiên cứu: Large genetic cohort (MR analysis)
Review
Nutraceuticals and pharmacological to balance the transitional microbiome to extend immunity during COVID-19 and other …
Dose: Probiotics, nutraceuticals
so với: None
Outcome: Immune response modulation in COVID-19
Hiệu quả: None
None
Đối tượng nghiên cứu: COVID-19 patients with gut dysbiosis
Randomized Controlled Trial
Zinc and L-Ascorbic Acid Dietary Supplementation Affected Antioxidant Status, Heat Shock Protein 70, and Some …
Dose: None
so với: Basal diet without supplementation
Outcome: Antioxidant status, hematology, growth in broilers
Hiệu quả: None
None
Đối tượng nghiên cứu: Broiler chickens
Randomized Controlled Trial
n=171
24 weeks
Double-blind
Probiotics with vitamin C for the prevention of upper respiratory tract symptoms in children aged …
Dose: 12.5 billion cfu/d
so với: placebo
Outcome: None
Hiệu quả: or 6
P=0.0300
Đối tượng nghiên cứu: None
Key Statistics
30
Nghiên cứu
10000
Người tham gia
↑
Positive
B
Xếp hạng
Referenced Papers
Nutrients
2025
4 trích dẫn
International journal of …
2025
2 trích dẫn
Journal of translational …
2024
2 trích dẫn
Frontiers in nutrition
2024
1 trích dẫn
Biological trace element …
2022
5 trích dẫn
Beneficial microbes
2021
18 trích dẫn
European journal of …
2021
Nutrients
2020
75 trích dẫn
Efficacy of vitamin C for the prevention and treatment of upper respiratory tract infection. A meta-analysis in children.
Meta-Analysis
European journal of …
2019
54 trích dẫn
Journal of evidence-based …
2017
134 trích dẫn
European journal of …
2017
18 trích dẫn
Zhongguo Zhong yao …
2017
European journal of …
2015
70 trích dẫn
World journal of …
2015
62 trích dẫn
Zhongguo Zhong yao …
2014
4 trích dẫn
Zhongguo Zhong yao …
2013
European journal of …
2012
225 trích dẫn
The British journal …
2012
40 trích dẫn
American family physician
2012
Journal of the …
2011
8 trích dẫn
International journal of …
2008
11 trích dẫn
American journal of …
2006
51 trích dẫn
Clinical evidence
2003
Clinical evidence
2003
The British journal …
2002
358 trích dẫn
Primary care
2002
56 trích dẫn
American family physician
2002
Canadian journal of …
2001
72 trích dẫn
Medicine and science …
2000
262 trích dẫn
Medicine and science …
2000
248 trích dẫn
Alternative medicine review …
2000
Canadian journal of …
1998
41 trích dẫn
Journal of applied …
1997
434 trích dẫn
International journal of …
1997
167 trích dẫn
Exercise immunology review
1997
27 trích dẫn
Respiration; international review …
1989
25 trích dẫn
Scandinavian journal of …
1977
56 trích dẫn
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
Liều lượng thường dùng
- general:
- 75-90 mg/day
- acuteillness:
- 1,000-2,000 mg/day
- immunesupport:
- 200-1,000 mg/day
Giới hạn trên: 2,000 mg/day
Liều lượng đã nghiên cứu
| Liều lượng | Thời gian | Hiệu quả | N |
|---|---|---|---|
| None | -- | Mixed | -- |
| None | -- | Neutral | -- |
| 12 circulating micronutrients | -- | Mixed | -- |
| Probiotics, nutraceuticals | -- | Positive | -- |
| None | -- | Positive | -- |
| 12.5 billion cfu/d | 24 weeks | Mixed | 171 |
| 45% | 988 weeks | Positive | 26282 |
| None | 13.0 weeks | Mixed | 3135 |
Thời điểm dùng tốt nhất: With meals; divide doses >500 mg for better absorption
Safety & Side Effects
Tác dụng phụ đã được báo cáo
- ⚠ Gastrointestinal distress (nausea, diarrhea, cramps) at high doses
- ⚠ Increased risk of kidney stones in susceptible individuals
- ⚠ Interference with certain lab tests (glucose, occult blood)
- ⚠ Iron overload risk in hemochromatosis patients
Tương tác đã biết
- ● Enhances non-heme iron absorption (beneficial or harmful depending on iron status)
- ● High doses may reduce effectiveness of certain chemotherapy agents
- ● May interfere with anticoagulant therapy (warfarin) at high doses
- ● Aluminum-containing antacids (increased aluminum absorption)
Mức hấp thụ tối đa cho phép: 2,000 mg/day
Luôn tham khảo ý kiến bác sĩ trước khi bắt đầu sử dụng bất kỳ thực phẩm bổ sung nào.Luôn tham khảo ý kiến chuyên gia y tế trước khi sử dụng bất kỳ thực phẩm chức năng nào.
Frequently Asked Questions
Does Vitamin C help with Upper Respiratory Tract Infections?
Based on 30 studies with 10,000 participants, there is moderate evidence from clinical studies that Vitamin C may support Upper Respiratory Tract Infections management. Our evidence grade is B (Good Evidence).
How much Vitamin C should I take for Upper Respiratory Tract Infections?
Studies have used various dosages. A commonly studied range is 75-90 mg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Vitamin C?
Reported side effects may include Gastrointestinal distress (nausea, diarrhea, cramps) at high doses, Increased risk of kidney stones in susceptible individuals, Interference with certain lab tests (glucose, occult blood), Iron overload risk in hemochromatosis patients. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Vitamin C and Upper Respiratory Tract Infections?
We rate the evidence as Grade B (Good Evidence). This rating is based on 30 peer-reviewed studies with 10,000 total participants. The overall direction of effect is positive.
Related Evidence
Các thành phần khác cho Upper Respiratory Tract Infections
Vitamin C cho các tình trạng khác
References
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