Beta-Glucan cho Upper Respiratory Tract Infections
A Bằng chứng Nhiều thử nghiệm lâm sàng lớn liên tục cho thấy những lợi ích đáng kể.Meta-analysis of 13 randomized controlled trials shows yeast beta-glucan may help reduce the incidence, number of episodes, and duration of upper respiratory tract infections compared to placebo. A 16-week RCT with 162 participants found 25% reduction in symptomatic cold infections.
<\/script>\n`;
},
get iframeSnippet() {
const domain = 'immunecited.com';
const params = 'ingredient\u003Dbeta\u002Dglucan\u0026condition\u003Dupper\u002Drespiratory\u002Dinfections';
return ``;
},
get activeSnippet() {
return this.method === 'script' ? this.scriptSnippet : this.iframeSnippet;
},
copySnippet() {
navigator.clipboard.writeText(this.activeSnippet).then(() => {
this.copied = true;
setTimeout(() => { this.copied = false; }, 2000);
});
}
}"
@keydown.escape.window="open = false"
@click.outside="open = false">
A
Kết luận
Meta-analysis of 13 randomized controlled trials shows yeast beta-glucan may help reduce the incidence, number of episodes, and duration of upper respiratory tract infections compared to placebo. A 16-week RCT with 162 participants found 25% reduction in symptomatic cold infections.
Key Study Findings
Randomized Controlled Trial
The anti-infective effect of β-glucans in children.
Dose: 10 mg
so với: Placebo
Outcome: Body weight
Hiệu quả: None
None
Đối tượng nghiên cứu: None
In Vitro
Dry blood spot samples to monitor immune-associated mRNA expression in intervention studies: Impact of Baker's …
Dose: 250 mg/d
so với: None
Outcome: oxidative stress markers
Hiệu quả: None
None
Đối tượng nghiên cứu: None
Randomized Controlled Trial
12 weeks
Double-blind
β -Glucan Improves Protective Qi Status in Adults with Protective Qi Deficiency-A Randomized, Placebo-Controlled, and …
Dose: None
so với: Placebo
Outcome: Protective Qi status improvement
Hiệu quả: None
None
Đối tượng nghiên cứu: Adults with Protective Qi deficiency
Meta-Analysis
Effects of yeast β-glucans for the prevention and treatment of upper respiratory tract infection in …
Dose: 95%
so với: placebo
Outcome: None
Hiệu quả: OR = 0.345
p < 0.001
Đối tượng nghiên cứu: healthy subjects
Randomized Controlled Trial
n=69
Soluble and Insoluble Yeast β-Glucan Differentially Affect Upper Respiratory Tract Infection in Marathon Runners: A …
Dose: 250 mL/d
so với: Placebo
Outcome: None
Hiệu quả: None
None
Đối tượng nghiên cứu: URTI patients
Randomized Controlled Trial
n=132
Double-blind
Beverage Containing Dispersible Yeast β-Glucan Decreases Cold/Flu Symptomatic Days After Intense Exercise: A Randomized Controlled …
Dose: 250 mL/d
so với: Placebo
Outcome: None
Hiệu quả: None
p < .05
Đối tượng nghiên cứu: URTI patients
Key Statistics
13
Nghiên cứu
2000
Người tham gia
↑
Positive
A
Xếp hạng
Referenced Papers
International journal for …
2024
5 trích dẫn
Methods (San Diego, …
2023
6 trích dẫn
Chinese journal of …
2022
2 trích dẫn
European journal of …
2021
21 trích dẫn
Journal of dietary …
2020
27 trích dẫn
Journal of medicinal …
2020
24 trích dẫn
Journal of the …
2019
47 trích dẫn
Nutrients
2019
34 trích dẫn
Journal of dietary …
2013
99 trích dẫn
American journal of …
2009
34 trích dẫn
Journal of sports …
2009
Medicine and science …
2008
71 trích dẫn
American journal of …
2008
45 trích dẫn
Journal of sports …
2006
94 trích dẫn
American journal of …
2004
107 trích dẫn
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
Liều lượng thường dùng
- general:
- 250-500 mg/day
- immunesupport:
- 250-750 mg/day
Giới hạn trên: No established UL
Liều lượng đã nghiên cứu
| Liều lượng | Thời gian | Hiệu quả | N |
|---|---|---|---|
| 10 mg | -- | Positive | -- |
| 250 mg/d | -- | Positive | -- |
| None | 12 weeks | Positive | -- |
| 95% | -- | Positive | -- |
| 250 mL/d | -- | Mixed | 69 |
| 250 mL/d | -- | Neutral | 132 |
| 900 mg | 16.0 weeks | Positive | 299 |
| 367 mg | 12.9 weeks | Positive | 34 |
Thời điểm dùng tốt nhất: On empty stomach for optimal immune activation
Safety & Side Effects
Tác dụng phụ đã được báo cáo
- ⚠ Generally very well tolerated
- ⚠ Mild gastrointestinal effects (bloating)
- ⚠ Allergic reactions in yeast-sensitive individuals
Tương tác đã biết
- ● Immunosuppressant medications (may counteract immunosuppression)
- ● Generally few known drug interactions
Mức hấp thụ tối đa cho phép: No established UL
Luôn tham khảo ý kiến bác sĩ trước khi bắt đầu sử dụng bất kỳ thực phẩm bổ sung nào.Luôn tham khảo ý kiến chuyên gia y tế trước khi sử dụng bất kỳ thực phẩm chức năng nào.
Frequently Asked Questions
Does Beta-Glucan help with Upper Respiratory Tract Infections?
Based on 13 studies with 2,000 participants, there is strong evidence from multiple clinical trials that Beta-Glucan may support Upper Respiratory Tract Infections management. Our evidence grade is A (Strong Evidence).
How much Beta-Glucan should I take for Upper Respiratory Tract Infections?
Studies have used various dosages. A commonly studied range is 250-500 mg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Beta-Glucan?
Reported side effects may include Generally very well tolerated, Mild gastrointestinal effects (bloating), Allergic reactions in yeast-sensitive individuals. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Beta-Glucan and Upper Respiratory Tract Infections?
We rate the evidence as Grade A (Strong Evidence). This rating is based on 13 peer-reviewed studies with 2,000 total participants. The overall direction of effect is positive.
Related Evidence
Các thành phần khác cho Upper Respiratory Tract Infections
References
- [1] Katarzyna Wzorek-Łyczko et al.. Int J Vitam Nutr Res. 2024. The anti-infective effect of β-glucans in children. doi:10.1024/0300-9831/a000793 PubMed
- [2] Brian K McFarlin et al.. Methods. 2023. Dry blood spot samples to monitor immune-associated mRNA expression in intervention studies: Impact of Baker's yeast beta glucan. doi:10.1016/j.ymeth.2023.09.006 PubMed
- [3] Jun-Rong Wu et al.. Chin J Integr Med. 2022. β -Glucan Improves Protective Qi Status in Adults with Protective Qi Deficiency-A Randomized, Placebo-Controlled, and Double-Blinded Trial. doi:10.1007/s11655-021-3444-0 PubMed
- [4] Kunxia Zhong et al.. Eur J Nutr. 2021. Effects of yeast β-glucans for the prevention and treatment of upper respiratory tract infection in healthy subjects: a systematic review … doi:10.1007/s00394-021-02566-4 PubMed
- [5] Eunice Mah et al.. J Diet Suppl. 2020. Beverage Containing Dispersible Yeast β-Glucan Decreases Cold/Flu Symptomatic Days After Intense Exercise: A Randomized Controlled Trial. doi:10.1080/19390211.2018.1495676 PubMed
- [6] Eunice Mah et al.. J Med Food. 2020. Soluble and Insoluble Yeast β-Glucan Differentially Affect Upper Respiratory Tract Infection in Marathon Runners: A Double-Blind, Randomized Placebo-Controlled Trial. doi:10.1089/jmf.2019.0076 PubMed
- [7] Tanita Dharsono et al.. J Am Coll Nutr. 2019. Effects of Yeast (1,3)-(1,6)-Beta-Glucan on Severity of Upper Respiratory Tract Infections: A Double-Blind, Randomized, Placebo-Controlled Study in Healthy Subjects. doi:10.1080/07315724.2018.1478339 PubMed
- [8] Malkanthi Evans et al.. Nutrients. 2019. Effect of a Euglena gracilis Fermentate on Immune Function in Healthy, Active Adults: A Randomized, Double-Blind, Placebo-Controlled Trial. doi:10.3390/nu11122926 PubMed
- [9] Brian K McFarlin et al.. J Diet Suppl. 2013. Baker's yeast beta glucan supplementation increases salivary IgA and decreases cold/flu symptomatic days after intense exercise. doi:10.3109/19390211.2013.820248 PubMed
- [10] E Angela Murphy et al.. Am J Physiol Regul Integr Comp Physiol. 2009. Benefits of oat beta-glucan and sucrose feedings on infection and macrophage antiviral resistance following exercise stress. doi:10.1152/ajpregu.00396.2009 PubMed
- [11] Shawn Talbott et al.. J Sports Sci Med. 2009. Effect of BETA 1, 3/1, 6 GLUCAN on Upper Respiratory Tract Infection Symptoms and Mood State in Marathon Athletes. PubMed
- [12] David C Nieman et al.. Med Sci Sports Exerc. 2008. Beta-glucan, immune function, and upper respiratory tract infections in athletes. doi:10.1249/MSS.0b013e31817057c2 PubMed
- [13] E A Murphy et al.. Am J Physiol Regul Integr Comp Physiol. 2008. Benefits of oat beta-glucan on respiratory infection following exercise stress: role of lung macrophages. doi:10.1152/ajpregu.00562.2007 PubMed
- [14] David C Nieman et al.. J Sports Sci. 2006. Nutritional strategies to counter stress to the immune system in athletes, with special reference to football. doi:10.1080/02640410500482982 PubMed
- [15] J M Davis et al.. Am J Physiol Regul Integr Comp Physiol. 2004. Effects of moderate exercise and oat beta-glucan on innate immune function and susceptibility to respiratory infection. doi:10.1152/ajpregu.00304.2003 PubMed
Tuyên bố miễn trừ FDA: Các tuyên bố này chưa được Cục Quản lý Thực phẩm và Dược phẩm (FDA) đánh giá. Các sản phẩm và thông tin trên trang web này không nhằm mục đích chẩn đoán, điều trị, chữa bệnh hoặc phòng ngừa bất kỳ bệnh nào. Xếp hạng bằng chứng được trình bày dựa trên phân tích của chúng tôi về nghiên cứu đã bình duyệt được công bố và không cấu thành tư vấn y khoa. Luôn tham khảo ý kiến chuyên gia y tế trước khi bắt đầu bất kỳ chế độ thực phẩm chức năng nào.