Beta-Glucan para Upper Respiratory Tract Infections

Q: Does Beta-Glucan help with Upper Respiratory Tract Infections?

Based on 13 studies with 2,000 participants, there is strong evidence from multiple clinical trials that Beta-Glucan may support Upper Respiratory Tract Infections management. Our evidence grade is A (Strong Evidence).

Q: How much Beta-Glucan should I take for Upper Respiratory Tract Infections?

Studies have used various dosages. A commonly studied range is 250-500 mg/day. Always consult your healthcare provider before starting any supplement regimen.

Q: Are there side effects of Beta-Glucan?

Reported side effects may include Generally very well tolerated, Mild gastrointestinal effects (bloating), Allergic reactions in yeast-sensitive individuals. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

Q: How strong is the evidence for Beta-Glucan and Upper Respiratory Tract Infections?

We rate the evidence as Grade A (Strong Evidence). This rating is based on 13 peer-reviewed studies with 2,000 total participants. The overall direction of effect is positive.

Meta-analysis of 13 randomized controlled trials shows yeast beta-glucan may help reduce the incidence, number of episodes, and duration of upper respiratory tract infections compared to placebo. A 16-week RCT with 162 participants found 25% reduction in symptomatic cold infections.

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Conclusão

Key Study Findings

Randomized Controlled Trial

The anti-infective effect of β-glucans in children.

Dose: 10 mg vs: Placebo Outcome: Body weight Efeito: None None

População: None

In Vitro

Dry blood spot samples to monitor immune-associated mRNA expression in intervention studies: Impact of Baker's …

Dose: 250 mg/d vs: None Outcome: oxidative stress markers Efeito: None None

População: None

Randomized Controlled Trial 12 weeks Double-blind

β -Glucan Improves Protective Qi Status in Adults with Protective Qi Deficiency-A Randomized, Placebo-Controlled, and …

Dose: None vs: Placebo Outcome: Protective Qi status improvement Efeito: None None

População: Adults with Protective Qi deficiency

Meta-Analysis

Effects of yeast β-glucans for the prevention and treatment of upper respiratory tract infection in …

Dose: 95% vs: placebo Outcome: None Efeito: OR = 0.345 p < 0.001

População: healthy subjects

Randomized Controlled Trial n=69

Soluble and Insoluble Yeast β-Glucan Differentially Affect Upper Respiratory Tract Infection in Marathon Runners: A …

Dose: 250 mL/d vs: Placebo Outcome: None Efeito: None None

População: URTI patients

Randomized Controlled Trial n=132 Double-blind

Beverage Containing Dispersible Yeast β-Glucan Decreases Cold/Flu Symptomatic Days After Intense Exercise: A Randomized Controlled …

Dose: 250 mL/d vs: Placebo Outcome: None Efeito: None p < .05

População: URTI patients

Key Statistics

Estudos

2000

Participantes

↑

Positive

Nota

Referenced Papers

The anti-infective effect of β-glucans in children. Review

International journal for … 2024 5 citações

Dry blood spot samples to monitor immune-associated mRNA expression in intervention studies: Impact of Baker's yeast beta glucan. Other

Methods (San Diego, … 2023 6 citações

β -Glucan Improves Protective Qi Status in Adults with Protective Qi Deficiency-A Randomized, Placebo-Controlled, and Double-Blinded Trial. RCT

Chinese journal of … 2022 2 citações

Effects of yeast β-glucans for the prevention and treatment of upper respiratory tract infection in healthy subjects: a systematic review … Meta-Analysis

European journal of … 2021 21 citações

Beverage Containing Dispersible Yeast β-Glucan Decreases Cold/Flu Symptomatic Days After Intense Exercise: A Randomized Controlled Trial. RCT

Journal of dietary … 2020 27 citações

Soluble and Insoluble Yeast β-Glucan Differentially Affect Upper Respiratory Tract Infection in Marathon Runners: A Double-Blind, Randomized Placebo-Controlled Trial. RCT

Journal of medicinal … 2020 24 citações

Effects of Yeast (1,3)-(1,6)-Beta-Glucan on Severity of Upper Respiratory Tract Infections: A Double-Blind, Randomized, Placebo-Controlled Study in Healthy Subjects. RCT

Journal of the … 2019 47 citações

Effect of a Euglena gracilis Fermentate on Immune Function in Healthy, Active Adults: A Randomized, Double-Blind, Placebo-Controlled Trial. RCT

Nutrients 2019 34 citações

Baker's yeast beta glucan supplementation increases salivary IgA and decreases cold/flu symptomatic days after intense exercise. RCT

Journal of dietary … 2013 99 citações

Benefits of oat beta-glucan and sucrose feedings on infection and macrophage antiviral resistance following exercise stress. Other

American journal of … 2009 34 citações

Effect of BETA 1, 3/1, 6 GLUCAN on Upper Respiratory Tract Infection Symptoms and Mood State in Marathon Athletes. Other

Journal of sports … 2009

Beta-glucan, immune function, and upper respiratory tract infections in athletes. RCT

Medicine and science … 2008 71 citações

Benefits of oat beta-glucan on respiratory infection following exercise stress: role of lung macrophages. Other

American journal of … 2008 45 citações

Nutritional strategies to counter stress to the immune system in athletes, with special reference to football. Review

Journal of sports … 2006 94 citações

Effects of moderate exercise and oat beta-glucan on innate immune function and susceptibility to respiratory infection. Other

American journal of … 2004 107 citações

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Dosagens Comumente Utilizadas

general:: 250-500 mg/day
immunesupport:: 250-750 mg/day

Limite superior: No established UL

Dosagens Estudadas em Pesquisas

Dosagem	Duração	Efeito	N
10 mg	--	Positive	--
250 mg/d	--	Positive	--
None	12 weeks	Positive	--
95%	--	Positive	--
250 mL/d	--	Mixed	69
250 mL/d	--	Neutral	132
900 mg	16.0 weeks	Positive	299
367 mg	12.9 weeks	Positive	34

Melhor horário: On empty stomach for optimal immune activation

Safety & Side Effects

Efeitos Colaterais Relatados

⚠ Generally very well tolerated
⚠ Mild gastrointestinal effects (bloating)
⚠ Allergic reactions in yeast-sensitive individuals

Interações Conhecidas

● Immunosuppressant medications (may counteract immunosuppression)
● Generally few known drug interactions

Ingestão máxima tolerável: No established UL

Consulte sempre o seu profissional de saúde antes de iniciar qualquer suplemento.Sempre consulte seu profissional de saúde antes de iniciar qualquer suplemento.

Frequently Asked Questions

Does Beta-Glucan help with Upper Respiratory Tract Infections?

Based on 13 studies with 2,000 participants, there is strong evidence from multiple clinical trials that Beta-Glucan may support Upper Respiratory Tract Infections management. Our evidence grade is A (Strong Evidence).

How much Beta-Glucan should I take for Upper Respiratory Tract Infections?

Studies have used various dosages. A commonly studied range is 250-500 mg/day. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Beta-Glucan?

Reported side effects may include Generally very well tolerated, Mild gastrointestinal effects (bloating), Allergic reactions in yeast-sensitive individuals. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Beta-Glucan and Upper Respiratory Tract Infections?

We rate the evidence as Grade A (Strong Evidence). This rating is based on 13 peer-reviewed studies with 2,000 total participants. The overall direction of effect is positive.

Related Evidence

Outros ingredientes para Upper Respiratory Tract Infections

Vitamin D A Zinc A Vitamin C B Echinacea B Andrographis B Garlic B

Veredito Rápido

Evidence Strength92%

High confidence

Detalhamento dos Estudos

RCT (7)Meta (1)Other (5)

Comparar Alternativas

Veja como outros ingredientes se comparam para esta condição.

Ver todos os ingredientes para Upper Respiratory Tract Infections

Saiba Mais

Aviso Legal da FDA: Estas declarações não foram avaliadas pela Food and Drug Administration. Os produtos e informações neste site não se destinam a diagnosticar, tratar, curar ou prevenir qualquer doença. As notas de evidência apresentadas são baseadas em nossa análise de pesquisas revisadas por pares publicadas e não constituem aconselhamento médico. Sempre consulte seu profissional de saúde antes de iniciar qualquer regime de suplementação.