Beta-Glucan para Upper Respiratory Tract Infections
A Evidências Vários grandes ensaios clínicos mostram de forma consistente benefícios significativos.Meta-analysis of 13 randomized controlled trials shows yeast beta-glucan may help reduce the incidence, number of episodes, and duration of upper respiratory tract infections compared to placebo. A 16-week RCT with 162 participants found 25% reduction in symptomatic cold infections.
Conclusão
Meta-analysis of 13 randomized controlled trials shows yeast beta-glucan may help reduce the incidence, number of episodes, and duration of upper respiratory tract infections compared to placebo. A 16-week RCT with 162 participants found 25% reduction in symptomatic cold infections.
Key Study Findings
População: None
População: None
População: Adults with Protective Qi deficiency
População: healthy subjects
População: URTI patients
População: URTI patients
Key Statistics
13
Estudos
2000
Participantes
Positive
Nota
Referenced Papers
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
Dosagens Comumente Utilizadas
- general:
- 250-500 mg/day
- immunesupport:
- 250-750 mg/day
Limite superior: No established UL
Dosagens Estudadas em Pesquisas
| Dosagem | Duração | Efeito | N |
|---|---|---|---|
| 10 mg | -- | Positive | -- |
| 250 mg/d | -- | Positive | -- |
| None | 12 weeks | Positive | -- |
| 95% | -- | Positive | -- |
| 250 mL/d | -- | Mixed | 69 |
| 250 mL/d | -- | Neutral | 132 |
| 900 mg | 16.0 weeks | Positive | 299 |
| 367 mg | 12.9 weeks | Positive | 34 |
Melhor horário: On empty stomach for optimal immune activation
Safety & Side Effects
Efeitos Colaterais Relatados
- ⚠ Generally very well tolerated
- ⚠ Mild gastrointestinal effects (bloating)
- ⚠ Allergic reactions in yeast-sensitive individuals
Interações Conhecidas
- ● Immunosuppressant medications (may counteract immunosuppression)
- ● Generally few known drug interactions
Ingestão máxima tolerável: No established UL
Consulte sempre o seu profissional de saúde antes de iniciar qualquer suplemento.Sempre consulte seu profissional de saúde antes de iniciar qualquer suplemento.
Frequently Asked Questions
Does Beta-Glucan help with Upper Respiratory Tract Infections?
How much Beta-Glucan should I take for Upper Respiratory Tract Infections?
Are there side effects of Beta-Glucan?
How strong is the evidence for Beta-Glucan and Upper Respiratory Tract Infections?
Related Evidence
Outros ingredientes para Upper Respiratory Tract Infections
References
- [1] Katarzyna Wzorek-Łyczko et al.. Int J Vitam Nutr Res. 2024. The anti-infective effect of β-glucans in children. doi:10.1024/0300-9831/a000793 PubMed
- [2] Brian K McFarlin et al.. Methods. 2023. Dry blood spot samples to monitor immune-associated mRNA expression in intervention studies: Impact of Baker's yeast beta glucan. doi:10.1016/j.ymeth.2023.09.006 PubMed
- [3] Jun-Rong Wu et al.. Chin J Integr Med. 2022. β -Glucan Improves Protective Qi Status in Adults with Protective Qi Deficiency-A Randomized, Placebo-Controlled, and Double-Blinded Trial. doi:10.1007/s11655-021-3444-0 PubMed
- [4] Kunxia Zhong et al.. Eur J Nutr. 2021. Effects of yeast β-glucans for the prevention and treatment of upper respiratory tract infection in healthy subjects: a systematic review … doi:10.1007/s00394-021-02566-4 PubMed
- [5] Eunice Mah et al.. J Diet Suppl. 2020. Beverage Containing Dispersible Yeast β-Glucan Decreases Cold/Flu Symptomatic Days After Intense Exercise: A Randomized Controlled Trial. doi:10.1080/19390211.2018.1495676 PubMed
- [6] Eunice Mah et al.. J Med Food. 2020. Soluble and Insoluble Yeast β-Glucan Differentially Affect Upper Respiratory Tract Infection in Marathon Runners: A Double-Blind, Randomized Placebo-Controlled Trial. doi:10.1089/jmf.2019.0076 PubMed
- [7] Tanita Dharsono et al.. J Am Coll Nutr. 2019. Effects of Yeast (1,3)-(1,6)-Beta-Glucan on Severity of Upper Respiratory Tract Infections: A Double-Blind, Randomized, Placebo-Controlled Study in Healthy Subjects. doi:10.1080/07315724.2018.1478339 PubMed
- [8] Malkanthi Evans et al.. Nutrients. 2019. Effect of a Euglena gracilis Fermentate on Immune Function in Healthy, Active Adults: A Randomized, Double-Blind, Placebo-Controlled Trial. doi:10.3390/nu11122926 PubMed
- [9] Brian K McFarlin et al.. J Diet Suppl. 2013. Baker's yeast beta glucan supplementation increases salivary IgA and decreases cold/flu symptomatic days after intense exercise. doi:10.3109/19390211.2013.820248 PubMed
- [10] E Angela Murphy et al.. Am J Physiol Regul Integr Comp Physiol. 2009. Benefits of oat beta-glucan and sucrose feedings on infection and macrophage antiviral resistance following exercise stress. doi:10.1152/ajpregu.00396.2009 PubMed
- [11] Shawn Talbott et al.. J Sports Sci Med. 2009. Effect of BETA 1, 3/1, 6 GLUCAN on Upper Respiratory Tract Infection Symptoms and Mood State in Marathon Athletes. PubMed
- [12] David C Nieman et al.. Med Sci Sports Exerc. 2008. Beta-glucan, immune function, and upper respiratory tract infections in athletes. doi:10.1249/MSS.0b013e31817057c2 PubMed
- [13] E A Murphy et al.. Am J Physiol Regul Integr Comp Physiol. 2008. Benefits of oat beta-glucan on respiratory infection following exercise stress: role of lung macrophages. doi:10.1152/ajpregu.00562.2007 PubMed
- [14] David C Nieman et al.. J Sports Sci. 2006. Nutritional strategies to counter stress to the immune system in athletes, with special reference to football. doi:10.1080/02640410500482982 PubMed
- [15] J M Davis et al.. Am J Physiol Regul Integr Comp Physiol. 2004. Effects of moderate exercise and oat beta-glucan on innate immune function and susceptibility to respiratory infection. doi:10.1152/ajpregu.00304.2003 PubMed
Aviso Legal da FDA: Estas declarações não foram avaliadas pela Food and Drug Administration. Os produtos e informações neste site não se destinam a diagnosticar, tratar, curar ou prevenir qualquer doença. As notas de evidência apresentadas são baseadas em nossa análise de pesquisas revisadas por pares publicadas e não constituem aconselhamento médico. Sempre consulte seu profissional de saúde antes de iniciar qualquer regime de suplementação.