Beta-Glucan 관련 상기도 감염
A 근거 여러 대규모 임상 시험이 일관되게 유의미한 효과를 보여줍니다.Meta-analysis of 13 randomized controlled trials shows yeast beta-glucan may help reduce the incidence, number of episodes, and duration of upper respiratory tract infections compared to placebo. A 16-week RCT with 162 participants found 25% reduction in symptomatic cold infections.
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A
결론
Meta-analysis of 13 randomized controlled trials shows yeast beta-glucan may help reduce the incidence, number of episodes, and duration of upper respiratory tract infections compared to placebo. A 16-week RCT with 162 participants found 25% reduction in symptomatic cold infections.
Key Study Findings
Randomized Controlled Trial
The anti-infective effect of β-glucans in children.
Dose: 10 mg
vs: Placebo
Outcome: Body weight
효과: None
None
대상 집단: None
In Vitro
Dry blood spot samples to monitor immune-associated mRNA expression in intervention studies: Impact of Baker's …
Dose: 250 mg/d
vs: None
Outcome: oxidative stress markers
효과: None
None
대상 집단: None
Randomized Controlled Trial
12 weeks
Double-blind
β -Glucan Improves Protective Qi Status in Adults with Protective Qi Deficiency-A Randomized, Placebo-Controlled, and …
Dose: None
vs: Placebo
Outcome: Protective Qi status improvement
효과: None
None
대상 집단: Adults with Protective Qi deficiency
Meta-Analysis
Effects of yeast β-glucans for the prevention and treatment of upper respiratory tract infection in …
Dose: 95%
vs: placebo
Outcome: None
효과: OR = 0.345
p < 0.001
대상 집단: healthy subjects
Randomized Controlled Trial
n=69
Soluble and Insoluble Yeast β-Glucan Differentially Affect Upper Respiratory Tract Infection in Marathon Runners: A …
Dose: 250 mL/d
vs: Placebo
Outcome: None
효과: None
None
대상 집단: URTI patients
Randomized Controlled Trial
n=132
Double-blind
Beverage Containing Dispersible Yeast β-Glucan Decreases Cold/Flu Symptomatic Days After Intense Exercise: A Randomized Controlled …
Dose: 250 mL/d
vs: Placebo
Outcome: None
효과: None
p < .05
대상 집단: URTI patients
Key Statistics
13
연구
2000
참여자
↑
Positive
A
등급
Referenced Papers
International journal for …
2024
5 인용
Methods (San Diego, …
2023
6 인용
Chinese journal of …
2022
2 인용
European journal of …
2021
21 인용
Journal of dietary …
2020
27 인용
Journal of medicinal …
2020
24 인용
Journal of the …
2019
47 인용
Nutrients
2019
34 인용
Journal of dietary …
2013
99 인용
American journal of …
2009
34 인용
Journal of sports …
2009
Medicine and science …
2008
71 인용
American journal of …
2008
45 인용
Journal of sports …
2006
94 인용
American journal of …
2004
107 인용
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
일반적으로 사용되는 용량
- general:
- 250-500 mg/day
- immunesupport:
- 250-750 mg/day
상한량: No established UL
연구에서 사용된 용량
| 용량 | 기간 | 효과 | N |
|---|---|---|---|
| 10 mg | -- | Positive | -- |
| 250 mg/d | -- | Positive | -- |
| None | 12 weeks | Positive | -- |
| 95% | -- | Positive | -- |
| 250 mL/d | -- | Mixed | 69 |
| 250 mL/d | -- | Neutral | 132 |
| 900 mg | 16.0 weeks | Positive | 299 |
| 367 mg | 12.9 weeks | Positive | 34 |
권장 복용 시간: On empty stomach for optimal immune activation
Safety & Side Effects
보고된 부작용
- ⚠ Generally very well tolerated
- ⚠ Mild gastrointestinal effects (bloating)
- ⚠ Allergic reactions in yeast-sensitive individuals
알려진 상호작용
- ● Immunosuppressant medications (may counteract immunosuppression)
- ● Generally few known drug interactions
일일 최대 섭취 허용량: No established UL
건강기능식품을 복용하기 전에 반드시 의료 전문가와 상담하십시오.
Frequently Asked Questions
Does Beta-Glucan help with 상기도 감염?
Based on 13 studies with 2,000 participants, there is strong evidence from multiple clinical trials that Beta-Glucan may support 상기도 감염 management. Our evidence grade is A (Strong Evidence).
How much Beta-Glucan should I take for 상기도 감염?
Studies have used various dosages. A commonly studied range is 250-500 mg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Beta-Glucan?
Reported side effects may include Generally very well tolerated, Mild gastrointestinal effects (bloating), Allergic reactions in yeast-sensitive individuals. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Beta-Glucan and 상기도 감염?
We rate the evidence as Grade A (Strong Evidence). This rating is based on 13 peer-reviewed studies with 2,000 total participants. The overall direction of effect is positive.
Related Evidence
References
- [1] Katarzyna Wzorek-Łyczko et al.. Int J Vitam Nutr Res. 2024. The anti-infective effect of β-glucans in children. doi:10.1024/0300-9831/a000793 PubMed
- [2] Brian K McFarlin et al.. Methods. 2023. Dry blood spot samples to monitor immune-associated mRNA expression in intervention studies: Impact of Baker's yeast beta glucan. doi:10.1016/j.ymeth.2023.09.006 PubMed
- [3] Jun-Rong Wu et al.. Chin J Integr Med. 2022. β -Glucan Improves Protective Qi Status in Adults with Protective Qi Deficiency-A Randomized, Placebo-Controlled, and Double-Blinded Trial. doi:10.1007/s11655-021-3444-0 PubMed
- [4] Kunxia Zhong et al.. Eur J Nutr. 2021. Effects of yeast β-glucans for the prevention and treatment of upper respiratory tract infection in healthy subjects: a systematic review … doi:10.1007/s00394-021-02566-4 PubMed
- [5] Eunice Mah et al.. J Diet Suppl. 2020. Beverage Containing Dispersible Yeast β-Glucan Decreases Cold/Flu Symptomatic Days After Intense Exercise: A Randomized Controlled Trial. doi:10.1080/19390211.2018.1495676 PubMed
- [6] Eunice Mah et al.. J Med Food. 2020. Soluble and Insoluble Yeast β-Glucan Differentially Affect Upper Respiratory Tract Infection in Marathon Runners: A Double-Blind, Randomized Placebo-Controlled Trial. doi:10.1089/jmf.2019.0076 PubMed
- [7] Tanita Dharsono et al.. J Am Coll Nutr. 2019. Effects of Yeast (1,3)-(1,6)-Beta-Glucan on Severity of Upper Respiratory Tract Infections: A Double-Blind, Randomized, Placebo-Controlled Study in Healthy Subjects. doi:10.1080/07315724.2018.1478339 PubMed
- [8] Malkanthi Evans et al.. Nutrients. 2019. Effect of a Euglena gracilis Fermentate on Immune Function in Healthy, Active Adults: A Randomized, Double-Blind, Placebo-Controlled Trial. doi:10.3390/nu11122926 PubMed
- [9] Brian K McFarlin et al.. J Diet Suppl. 2013. Baker's yeast beta glucan supplementation increases salivary IgA and decreases cold/flu symptomatic days after intense exercise. doi:10.3109/19390211.2013.820248 PubMed
- [10] E Angela Murphy et al.. Am J Physiol Regul Integr Comp Physiol. 2009. Benefits of oat beta-glucan and sucrose feedings on infection and macrophage antiviral resistance following exercise stress. doi:10.1152/ajpregu.00396.2009 PubMed
- [11] Shawn Talbott et al.. J Sports Sci Med. 2009. Effect of BETA 1, 3/1, 6 GLUCAN on Upper Respiratory Tract Infection Symptoms and Mood State in Marathon Athletes. PubMed
- [12] David C Nieman et al.. Med Sci Sports Exerc. 2008. Beta-glucan, immune function, and upper respiratory tract infections in athletes. doi:10.1249/MSS.0b013e31817057c2 PubMed
- [13] E A Murphy et al.. Am J Physiol Regul Integr Comp Physiol. 2008. Benefits of oat beta-glucan on respiratory infection following exercise stress: role of lung macrophages. doi:10.1152/ajpregu.00562.2007 PubMed
- [14] David C Nieman et al.. J Sports Sci. 2006. Nutritional strategies to counter stress to the immune system in athletes, with special reference to football. doi:10.1080/02640410500482982 PubMed
- [15] J M Davis et al.. Am J Physiol Regul Integr Comp Physiol. 2004. Effects of moderate exercise and oat beta-glucan on innate immune function and susceptibility to respiratory infection. doi:10.1152/ajpregu.00304.2003 PubMed
FDA 면책 조항: 이 내용은 미국 식품의약국(FDA)의 평가를 받지 않았습니다. 이 웹사이트의 제품 및 정보는 질병의 진단, 치료, 완치 또는 예방을 목적으로 하지 않습니다. 제시된 근거 등급은 발표된 동료 심사 연구에 대한 우리의 분석에 기반하며, 의학적 조언을 구성하지 않습니다. 건강기능식품 복용을 시작하기 전에 반드시 의료 전문가와 상담하십시오.