아연 관련 상기도 감염
A 근거 여러 대규모 임상 시험이 일관되게 유의미한 효과를 보여줍니다.7건의 시험 메타분석에서 발병 24시간 이내에 시작한 75mg/일 이상의 아연 로젠지가 감기 지속기간을 33% 줄일 수 있음을 보여줍니다. 아세트산아연 로젠지 80~92mg/일은 지속기간을 40% 줄였습니다. 75mg/일 미만 용량은 효과가 없었습니다.
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A
결론
7건의 시험 메타분석에서 발병 24시간 이내에 시작한 75mg/일 이상의 아연 로젠지가 감기 지속기간을 33% 줄일 수 있음을 보여줍니다. 아세트산아연 로젠지 80~92mg/일은 지속기간을 40% 줄였습니다. 75mg/일 미만 용량은 효과가 없었습니다.
Key Study Findings
Observational Study
n=107
Open-label
Additive effect of free-choice olfactory training combined with pharmacotherapy: A retrospective analysis of post-viral olfactory …
Dose: tokishakuyakusan, zinc sulfate, methylcobalamin
vs: medication alone
Outcome: olfactory function improvement via T&T olfactometry
효과: OR=4.96
p=0.009
대상 집단: patients with post-viral olfactory dysfunction (non-COVID)
Review
Exploiting the vulnerability of SARS-CoV-2 with a partnership of mucosal immune function and nutrition: a …
Dose: None
vs: None
Outcome: None
효과: None
None
대상 집단: None
Review
UCI Sports Nutrition Project: The Role of Nutrition in the Prevention and Management of Illnesses …
Dose: None
vs: None
Outcome: None
효과: None
None
대상 집단: Elite/professional cyclists nutrition review
Meta-Analysis
Effect of Oral Nutritional Supplementation on Health-Related Outcomes and Nutritional Biomarkers in Children and Adolescents …
Dose: Various oral nutritional supplements
vs: Standard diet or placebo
Outcome: Health outcomes and nutritional biomarkers
효과: None
None
대상 집단: Children/adolescents with undernutrition
Controlled Clinical Trial
n=120
5 weeks
Single-blind
Single-Center-Single-Blinded Clinical Trial to Evaluate the Efficacy of a Nutraceutical Containing Boswellia Serrata, Bromelain, Zinc, …
Dose: 20 or 30 days treatment
vs: Standard treatment only (nasal aerosol)
Outcome: Otoscopy, impedance, fibroscopy, pure auditory test
효과: None
None
대상 집단: Children with otitis media
Review
Associations of fine particulate matter and constituents with pediatric emergency room visits for respiratory diseases …
Dose: 31 μg
vs: None
Outcome: None
효과: None
None
대상 집단: respiratory disease
Key Statistics
15
연구
1500
참여자
↑
Positive
A
등급
Referenced Papers
Auris, nasus, larynx
2026
International journal of …
2025
2 인용
Nutrition research reviews
2025
Nutrients
2024
2 인용
Healthcare (Basel, Switzerland)
2022
7 인용
Gene reports
2021
33 인용
International journal of …
2021
26 인용
Archivio italiano di …
2019
117 인용
Indian journal of …
2019
3 인용
PloS one
2018
48 인용
Antimicrobial resistance and …
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46 인용
Journal of evidence-based …
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134 인용
European journal of …
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18 인용
Allergologia et immunopathologia
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mBio
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113 인용
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WITHDRAWN: Zinc for the common cold.
Systematic Review
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Systematic Review
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Southern medical journal
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3 인용
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
일반적으로 사용되는 용량
- general:
- 8-11 mg/day
- coldtreatment:
- 75-100 mg/day elemental zinc (lozenges, within 24h of onset, up to 2 weeks)
- immunesupport:
- 15-30 mg/day
상한량: 40 mg/day (long-term)
연구에서 사용된 용량
| 용량 | 기간 | 효과 | N |
|---|---|---|---|
| tokishakuyakusan, zinc sulfate, methylcobalamin | -- | Positive | 107 |
| None | -- | Mixed | -- |
| None | -- | Mixed | -- |
| Various oral nutritional supplements | -- | Positive | -- |
| 20 or 30 days treatment | 5 weeks | Positive | 120 |
| 31 μg | -- | Neutral | -- |
| 94.57% | -- | Mixed | -- |
| None | -- | Mixed | 387 |
권장 복용 시간: Lozenges: dissolve slowly in mouth every 2-3h at cold onset; Supplements: with food to minimize nausea
Safety & Side Effects
보고된 부작용
- ⚠ Nausea and vomiting (especially on an empty stomach)
- ⚠ Metallic taste in the mouth
- ⚠ Copper depletion with chronic high-dose use (>40 mg/day)
- ⚠ Headache and diarrhea
알려진 상호작용
- ● Copper supplements (zinc inhibits copper absorption at doses >40 mg/day)
- ● Tetracycline and quinolone antibiotics (mutual absorption reduction)
- ● Penicillamine (zinc reduces absorption of this rheumatoid arthritis drug)
- ● Iron supplements (mutual absorption interference when taken together)
일일 최대 섭취 허용량: 40 mg/day (long-term)
건강기능식품을 복용하기 전에 반드시 의료 전문가와 상담하십시오.
Frequently Asked Questions
Does 아연 help with 상기도 감염?
Based on 15 studies with 1,500 participants, there is strong evidence from multiple clinical trials that 아연 may support 상기도 감염 management. Our evidence grade is A (Strong Evidence).
How much 아연 should I take for 상기도 감염?
Studies have used various dosages. A commonly studied range is 8-11 mg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of 아연?
Reported side effects may include Nausea and vomiting (especially on an empty stomach), Metallic taste in the mouth, Copper depletion with chronic high-dose use (>40 mg/day), Headache and diarrhea. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for 아연 and 상기도 감염?
We rate the evidence as Grade A (Strong Evidence). This rating is based on 15 peer-reviewed studies with 1,500 total participants. The overall direction of effect is positive.
Related Evidence
References
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FDA 면책 조항: 이 내용은 미국 식품의약국(FDA)의 평가를 받지 않았습니다. 이 웹사이트의 제품 및 정보는 질병의 진단, 치료, 완치 또는 예방을 목적으로 하지 않습니다. 제시된 근거 등급은 발표된 동료 심사 연구에 대한 우리의 분석에 기반하며, 의학적 조언을 구성하지 않습니다. 건강기능식품 복용을 시작하기 전에 반드시 의료 전문가와 상담하십시오.